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1-pyrazolyl, 5-, 6-disubstituted indazole derivatives as LRRK2 inhibitors, pharmaceutical compositions, and uses thereof |
Hua Zhou, John J. Acton, III, Michael J. Ardolino, Yi-Heng Chen, Peter H. Fuller +15 more |
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Indazolyl-spiro[2.2]pentane-carbonitrile derivatives as LRRK2 inhibitors, pharmaceutical compositions, and uses thereof |
David A. Candito, Thomas H. Graham, John J. Acton, III, Ryan Chau, Joanna L. Chen +13 more |
2021-11-02 |
| 10508108 |
Tricyclic compounds as inhibitors of mutant IDH enzymes |
Christian Fischer, Stephane L. Bogen, Matthew L. Childers, Francesc Xavier Fradera Llinas, J. Michael Ellis +17 more |
2019-12-17 |
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Inhibitors of IRAK4 activity |
Michael D. Altman, Brian M. Andresen, Jason D. Brubaker, Matthew L. Childers, Anthony Donofrio +9 more |
2018-05-15 |
| 9938281 |
Purine inhibitors of human phosphatidylinositol 3-kinase delta |
Abdelghani Achab, Michael D. Altman, Yongqi Deng, Jason Katz, Joey L. Methot +16 more |
2018-04-10 |
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Inhibitors of IRAK4 activity |
Michael D. Altman, Jason D. Brubaker, Matthew L. Childers, Anthony Donofrio, Thierry O. Fischmann +8 more |
2018-04-03 |
| 9926330 |
Inhibitors of IRAK4 activity |
Michael D. Altman, Jason D. Brubaker, Matthew L. Childers, Anthony Donofrio, Thierry O. Fischmann +8 more |
2018-03-27 |
| 9730940 |
Purine inhibitors of human phosphatidylinositol 3-kinase delta |
Abdelghani Achab, Michael D. Altman, Yongqi Deng, Timothy J. Guzi, Jason Katz +12 more |
2017-08-15 |
| 9670196 |
Thiazole-substituted aminoheteroaryls as Spleen Tyrosine Kinase inhibitors |
Thomas Miller, Alessia Petrocchi, Eric T. Romeo, Dilrukshi Vitharana, Alan B. Northrup +2 more |
2017-06-06 |
| 9586931 |
Triazolyl derivatives as Syk inhibitors |
Michelle R. Machacek, Eric T. Romeo, Matthew Christopher, Michael D. Altman, Alan B. Northrup +17 more |
2017-03-07 |
| 9416111 |
Substituted diazine and triazine spleen tyrosine kinease (Syk) inhibitors |
Andrew M. Haidle, Michael D. Altman, Matthew Christopher, John Michael Ellis, Christian Fischer +2 more |
2016-08-16 |
| 9376418 |
Substituted pyridine spleen tyrosine kinase (SYK) inhibitors |
Andrew M. Haidle, Sandra Lee Knowles, Denis Deschenes, Jason Burch, Joel Robichaud +12 more |
2016-06-28 |
| 9353066 |
Substituted phenyl-Spleen Tyrosine Kinase (Syk) inhibitors |
Andrew M. Haidle, Jason Burch, Daniel Guay, Jacques Yves Gauthier, Joel Robichaud +5 more |
2016-05-31 |
| 9290490 |
Aminopyrimidines as Syk inhibitors |
Michael D. Altman, Kaleen Konrad Childers, Maria Emilia Di Francesco, John Michael Ellis, Christian Fischer +7 more |
2016-03-22 |
| 9242984 |
Pyrazolyl derivatives as Syk inhibitors |
Michelle R. Machacek, Michael D. Altman, Eric T. Romeo, Dilrukshi Vitharana, Brandon D. Cash +21 more |
2016-01-26 |
| 9145391 |
Bipyridylaminopyridines as Syk inhibitors |
Denis Deschenes, Michael D. Altman, John Michael Ellis, Christian Fischer, Andrew M. Haidle +14 more |
2015-09-29 |
| 9096559 |
4-carboxybenzylamino derivatives as histone deacetylase inhibitors |
Paul E. Harrington, Richard W. Heidebrecht, Thomas Miller, Karin M. Otte, Phieng Siliphaivanh +4 more |
2015-08-04 |
| 8735417 |
Aminopyrimidines as Syk inhibitors |
Michael D. Altman, Kenneth L. Arrington, Jason Burch, Bernard Cote, Jean-Francois Fournier +9 more |
2014-05-27 |
| 8551984 |
Aminopyrimidines as SYK inhibitors |
Michael D. Altman, Brian M. Andresen, Kenneth L. Arrington, Jason Burch, Kaleen Konrad Childers +24 more |
2013-10-08 |
| 8455477 |
Therapeutic compounds |
Jason Katz, James P. Jewell, Joon Jung, Yongquan Hou, Rachel N. MacCoss +1 more |
2013-06-04 |
| 8389553 |
4-carboxybenzylamino derivatives as histone deacetylase inhibitors |
Paul E. Harrington, Thomas Miller, Matthew G. Stanton, Paul Tempest, David J. Witter |
2013-03-05 |
| 8329722 |
Inhibitors of janus kinases and/or 3-phosphoinositide-dependent protein kinase-1 |
Tony Siu, Jonathan R. Young, Michael D. Altman, Alan B. Northrup, Ekaterina Kozina +5 more |
2012-12-11 |
| 8158825 |
Modified malonate derivatives |
Jonathan B. Grimm, Paul E. Harrington, Richard W. Heidebrecht, Thomas Miller, Karin M. Otte +6 more |
2012-04-17 |
| 8119652 |
Aryl-fused spirocyclic compounds |
Christopher Hamblett, Dawn M. Mampreian, Joey L. Methot, Thomas Miller, Paul Tempest |
2012-02-21 |
| 8026260 |
Histone deacetylase inhibitors with aryl-pyrazolyl-motifs |
Joshua Close, Richard W. Heidebrecht, Thomas Miller, David L. Sloman, Matthew G. Stanton +2 more |
2011-09-27 |
