| 11279712 |
Macrocyclic compounds that inhibit MCL-1 protein |
Sean P. Brown, Yunxiao Li, Brian Alan LANMAN, Jonathan D. Low, Ana Elena Minatti +2 more |
2022-03-22 |
$646,313,000 |
| 11224601 |
Compounds that inhibits MCL-1 protein |
Kate Ashton, Sean P. Brown, Matthew R. Kaller, Todd J. Kohn, Brian Alan LANMAN +7 more |
2022-01-18 |
$641,433,000 |
| 10947223 |
Substituted oxazines as beta-secretase inhibitors |
Jennifer R. Allen, Matthew P. Bourbeau, Ning Chen, Michael J. Frohn, Qingyian Liu +1 more |
2021-03-16 |
$1,023,364,000 |
| 10889579 |
Thiazine derivatives as β-secretase inhibitors and methods of use |
Matthew P. Bourbeau, Qingyian Liu |
2021-01-12 |
$484,084,000 |
| 10889581 |
Cyclopropyl fused thiazine derivatives as beta-secretase inhibitors and methods of use |
Jennifer R. Allen, Albert Amegadzie, Matthew P. Bourbeau, Jian Chen, Michael J. Frohn +5 more |
2021-01-12 |
$484,084,000 |
| 10821115 |
Compounds that inhibit Mcl-1 protein |
Kate Ashton, Sean P. Brown, Matthew R. Kaller, Todd J. Kohn, Brian Alan LANMAN +7 more |
2020-11-03 |
$280,862,000 |
| 10632128 |
Compounds that inhibit Mcl-1 protein |
Kate Ashton, Sean P. Brown, Matthew R. Kaller, Todd J. Kohn, Brian Alan LANMAN +7 more |
2020-04-28 |
$393,385,000 |
| 9611261 |
Perfluorinated cyclopropyl fused 1,3-oxazin-2-amine compounds as beta-secretase inhibitors and methods of use |
Ana Elena Minatti, Jonathan D. Low, Jennifer R. Allen, Albert Amegadzie, James Brown +12 more |
2017-04-04 |
$276,197,000 |
| 9556135 |
Amino-dihydrothiazine and amino-dioxido dihydrothiazine compounds as beta-secretase antagonists and methods of use |
Richard T. Lewis, Jennifer R. Allen, Yuan Cheng, Deborah Choquette, Oleg Epstein +18 more |
2017-01-31 |
$569,268,000 |
| 9550762 |
Cyclopropyl fused thiazin-2-amine compounds as beta-secretase inhibitors and methods of use |
Jennifer R. Allen, Albert Amegadzie, Matthew P. Bourbeau, James Brown, Jian Chen +21 more |
2017-01-24 |
$492,282,000 |
| 9096559 |
4-carboxybenzylamino derivatives as histone deacetylase inhibitors |
Richard W. Heidebrecht, Solomon D. Kattar, Thomas Miller, Karin M. Otte, Phieng Siliphaivanh +4 more |
2015-08-04 |
$86,770,000 |
| 9085576 |
Perfluorinated cyclopropyl fused 1,3-oxazin-2-amine compounds as beta-secretase inhibitors and methods of use |
Ana Elena Minatti, Jonathan D. Low, Jennifer R. Allen, Albert Amegadzie, James Brown +12 more |
2015-07-21 |
$288,742,000 |
| 8952037 |
Heteroaryloxycarbocyclyl compounds as PDE10 inhibitors |
Jennifer R. Allen, Michael J. Frohn, Essa Hu, Alexander J. Pickrell, Robert M. Rzasa +1 more |
2015-02-10 |
$136,135,000 |
| 8946230 |
Aryl- and heteroaryl- nitrogen-heterocyclic compounds as PDE10 inhibitors |
Jennifer R. Allen, Kristin L. Andrews, Michael J. Frohn, Alexander J. Pickrell, Robert M. Rzasa |
2015-02-03 |
$173,070,000 |
| 8791147 |
Calcium receptor modulating agents |
Christopher H. Fotsch |
2014-07-29 |
$181,508,000 |
| 8759532 |
Pyridine and pyrimidine derivatives as phosphodiesterase 10 inhibitors |
Jennifer R. Allen, Kaustav Biswas, Frank Chavez, Ning Chen, Frenel F. De Morin +14 more |
2014-06-24 |
$237,467,000 |
| 8637500 |
Aminopyridine and carboxypyridine compounds as phosphodiesterase 10 inhibitors |
Jennifer R. Allen, Ning Chen, James R. Falsey, Michael J. Frohn, Essa Hu Harrington +10 more |
2014-01-28 |
$269,215,000 |
| 8389553 |
4-carboxybenzylamino derivatives as histone deacetylase inhibitors |
Solomon D. Kattar, Thomas Miller, Matthew G. Stanton, Paul Tempest, David J. Witter |
2013-03-05 |
$77,218,000 |
| 8349831 |
Calcium receptor modulating agents |
Thomas Coulter, Adam James Davenport, Christopher H. Fotsch, Chiara Ghiron, Michael G. Kelly +4 more |
2013-01-08 |
$109,277,000 |
| 8334317 |
Calcium receptor modulating agents |
Thomas Coulter, Christopher H. Fotsch, Chiara Ghiron, Michael G. Kelly, Philip Miller +3 more |
2012-12-18 |
$226,841,000 |
| 8324396 |
Derivatives of urea and related diamines, methods for their manufacture, and uses therefor |
Pierre Deprez, Christopher H. Fotsch, Sarah Lively, Kanaka Pattabiraman, David J. St. Jean, Jr. +1 more |
2012-12-04 |
$126,296,000 |
| 8318718 |
Pyridine and pyrimidine derivatives as phosphodiesterase 10 inhibitors |
Jennifer R. Allen, Biswas Kaustav, Frank Chavez, Ning Chen, Frenel F. De Morin +14 more |
2012-11-27 |
$128,265,000 |
| 8158825 |
Modified malonate derivatives |
Jonathan B. Grimm, Richard W. Heidebrecht, Thomas Miller, Karin M. Otte, Phieng Siliphaivanh +6 more |
2012-04-17 |
$210,725,000 |
