| 9745295 |
Thiazole-substituted aminoheteroaryls as spleen tyrosine kinase inhibitors |
Neville J. Anthony, Brian M. Andresen, Alan B. Northrup, Kaleen Konrad Childers, Anthony Donofrio +14 more |
2017-08-29 |
$63,155,000 |
| 9586931 |
Triazolyl derivatives as Syk inhibitors |
Michelle R. Machacek, Eric T. Romeo, Solomon D. Kattar, Matthew Christopher, Michael D. Altman +17 more |
2017-03-07 |
$72,118,000 |
| 9353066 |
Substituted phenyl-Spleen Tyrosine Kinase (Syk) inhibitors |
Andrew M. Haidle, Jason Burch, Jacques Yves Gauthier, Joel Robichaud, Jean-Francois Fournier +5 more |
2016-05-31 |
$68,752,000 |
| 9242984 |
Pyrazolyl derivatives as Syk inhibitors |
Michelle R. Machacek, Michael D. Altman, Eric T. Romeo, Dilrukshi Vitharana, Brandon D. Cash +21 more |
2016-01-26 |
$42,047,000 |
| 8551984 |
Aminopyrimidines as SYK inhibitors |
Michael D. Altman, Brian M. Andresen, Kenneth L. Arrington, Jason Burch, Kaleen Konrad Childers +24 more |
2013-10-08 |
$45,159,000 |
| 7622501 |
Nitric oxide releasing prodrugs of diaryl-2-(5H)-furanones as cyclooxygenase-2 inhibitors |
Claude Dufresne, Carl Berthelette, Lianhai Li, Michel Gallant, Patrick Lacombe +3 more |
2009-11-24 |
$81,178,000 |
| 7144913 |
Dihydropyrrolo[1,2-a]indole and tetrahydropyrido[1,2-a]-indole derivatives as prostaglandin d2 receptor antagonists |
Zhaoyin Wang, Christian Beaulieu, Claude Dufresne, Yves LeBlanc |
2006-12-05 |
$64,547,000 |
| 7019022 |
Substituted tetrahydrocarbazole and cyclopentanoindole derivatives |
Christian Beaulieu, Zhaoyin Wang, Robert Zamboni |
2006-03-28 |
$94,570,000 |
| 6841564 |
Tri-aryl-substituted-ethane PDE4 inhibitors |
Richard Freisen, Yves Ducharme, Bernard Cote, Marc Blouin, Evelyn Martins +4 more |
2005-01-11 |
$70,720,000 |
| 6743802 |
Alkyne-aryl phosphodiesterase-4 inhibitors |
Mario Girard, Pierre Hamel, Sebastien Laliberte, Richard Friesen |
2004-06-01 |
$135,889,000 |
| 6677351 |
1-biaryl-1,8-naphthyridin-4-one phosphodiesterase-4 inhibitors |
Chun Sing Li, Mario Girard, Pierre Hamel, Sebastien Laliberte, Richard Friesen +1 more |
2004-01-13 |
$70,543,000 |
| RE38103 |
5-methanesulfonamido-1-indanones as an inhibitor of cyclooxygenase-2 |
Chun Sing Li |
2003-04-29 |
|
| 6399636 |
Tri-aryl-substituted-ethane PDE4 inhibitors |
Richard Freisen, Yves Ducharme, Bernard Cote, Marc Blouin, Evelyn Martins +4 more |
2002-06-04 |
$70,474,000 |
| 6329421 |
Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2 |
Petpiboon Prasit, Zhaoyin Wang, Serge Leger, Michel Therien |
2001-12-11 |
$173,380,000 |
| 6200993 |
Heterosubstituted pyridine derivatives as PDE4 inhibitors |
Bernard Cote, Richard Friesen, Richard Frenette, Mario Girard, Yves Girard +5 more |
2001-03-13 |
$219,477,000 |
| 5968958 |
5-Methanesulfonamido-3H-isobenzofuran-1-ones as inhibitors of cyclooxygenase-2 |
Chun Sing Li, Nathalie Ouimet |
1999-10-19 |
$89,172,000 |
| 5856322 |
Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists |
Michel Belley, Serge Leger, Patrick Roy, Marc Labelle, Yi Bin Xiang |
1999-01-05 |
$160,086,000 |
| 5817700 |
Bisaryl cyclobutenes derivatives as cyclooxygenase inhibitors |
Daniel Dube, Rejean Fortin, Richard Frenette, Richard Friesen, Sylvie Prescott |
1998-10-06 |
$131,947,000 |
| 5733909 |
Diphenyl stilbenes as prodrugs to COX-2 inhibitors |
Cameron Black, Mario Girard, Zhaoyin Wang |
1998-03-31 |
$227,729,000 |
| 5710170 |
Tri-aryl ethane derivatives as PDE IV inhibitors |
Yves Girard, Yves Ducharme, Marc Blouin, Pierre Hamel, Mario Girard |
1998-01-20 |
$89,344,000 |
| 5710160 |
Diphenyl pyridyl ethane derivatives as PDE IV inhibitors |
Yves Girard, Yves Ducharme |
1998-01-20 |
$89,344,000 |
| 5639780 |
N-benzyl indol-3-yl butanoic acid derivatives as cyclooxygenase inhibitors |
Cheuk K. Lau, Cameron Black, Jacques Yves Gauthier, Yves LeBlanc, Patrick Roy +2 more |
1997-06-17 |
$146,641,000 |
| 5604253 |
N-benzylindol-3-yl propanoic acid derivatives as cyclooxygenase inhibitors |
Cheuk K. Lau, Cameron Black, Jacques Yves Gauthier, Yves LeBlanc, Patrick Roy +2 more |
1997-02-18 |
$138,405,000 |
| 5604260 |
5-methanesulfonamido-1-indanones as an inhibitor of cyclooxygenase-2 |
Chun Sing Li |
1997-02-18 |
$138,405,000 |
| 5565473 |
Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists |
Michel Belley, Serge Leger, Marc Labelle, Patrick Roy, Yi Bin Xiang |
1996-10-15 |
$52,729,000 |