| 12427159 |
Hydroxypyrrolidine-substituted arylsulfonamide compounds with selective activity in voltage-gated sodium channels |
Anthony J. Roecker, Deping Wang, Xiu Wang, Xuanjia Peng |
2025-09-30 |
|
| 12344595 |
2-amino-n-phenyl-nicotinamides as NAV1.8 inhibitors |
Michael J. Breslin, Christopher James Bungard, Harry R. Chobanian, Kristen L. G. Jones, Jian Liu +5 more |
2025-07-01 |
|
| 12246008 |
4-amino or 4-alkoxy-substituted aryl sulfonamide compounds with selective activity in voltage-gated sodium channels |
Christopher James Bungard, Helen Chen, Jason M. Cox, Liangqin Guo, Michael J. Kelly, III +9 more |
2025-03-11 |
|
| 12195445 |
2-amino-N-heteroaryl-nicotinamides as Nav1.8 inhibitors |
Ashok Arasappan, Ian M. Bell, Michael J. Breslin, Christopher James Bungard, Christopher S. Burgey +11 more |
2025-01-14 |
|
| 11802122 |
2-oxoimidazolidine-4-carboxamides as NAv1.8 inhibitors |
Ashok Arasappan, Ian M. Bell, Christopher James Bungard, Christopher S. Burgey, Jason M. Cox +7 more |
2023-10-31 |
$669,245,000 |
| 11377438 |
2-amino-n-heteroaryl-nicotinamides as Nav1.8 inhibitors |
Ashok Arasappan, Ian M. Bell, Michael J. Breslin, Christopher James Bungard, Christopher S. Burgey +11 more |
2022-07-05 |
$309,260,000 |
| 10968210 |
Diamino-alkylamino-linked arylsulfonamide compounds with selective activity in voltage-gated sodium channels |
Thomas J. Greshock, James Mulhearn, Anthony J. Roecker, Tianying Jian, Gang Zhou +9 more |
2021-04-06 |
$229,405,000 |
| 10519147 |
Diamino-alkylamino-linked arylsulfonamide compounds with selective activity in voltage-gated sodium channels |
Thomas J. Greshock, James Mulhearn, Liangqin Guo, Ting Zhang, Deping Wang +8 more |
2019-12-31 |
$136,403,000 |
| 10442778 |
N1-phenylpropane-1,2-diamine compounds with selective activity in voltage-gated sodium channels |
Anthony J. Roecker, Thomas J. Greshock, Joseph E. Pero, Michael J. Kelly, III, Ting Zhang |
2019-10-15 |
$166,889,000 |
| 9624208 |
Benzoxazolinone compounds with selective activity in voltage-gated sodium channels |
Joseph E. Pero, Hannah D. G. F. Lehman, Michael J. Kelly, III, Lianyun Zhao, Michael A. Rossi +5 more |
2017-04-18 |
$55,580,000 |
| 9586968 |
Bicycloamine-substituted-N-benzenesulfonamide compounds with selective activity in voltage-gated sodium channels |
Anthony J. Roecker, Melissa Egbertson, Kristen L. G. Jones, Dansu Li, Xiu Wang +1 more |
2017-03-07 |
$72,118,000 |
| 9388179 |
N-substituted indazole sulfonamide compounds with selective activity in voltage-gated sodium channels |
Joseph E. Pero, Hannah D. G. F. Lehman, Michael A. Rossi, Michael J. Kelly, III |
2016-07-12 |
$72,848,000 |
| 9315518 |
Imidazopyridin-2-one derivatives |
Hannah Fiji, Michael J. Kelly, III, Jeffrey Kern, Joseph E. Pero, Alexander Joseph Reif +1 more |
2016-04-19 |
$73,692,000 |
| 9273040 |
Benzoxazolinone compounds with selective activity in voltage-gated sodium channels |
Joseph E. Pero, Hannah Fiji, Michael J. Kelly, III, Pablo de Leon, Michael A. Rossi +8 more |
2016-03-01 |
$86,173,000 |
| 9108937 |
Positive allosteric modulators of mGluR2 |
Michael J. Kelly, III, Timothy J. Hartingh |
2015-08-18 |
$66,173,000 |
| 9062059 |
Pyrimidine PDE10 inhibitors |
Christopher D. Cox, Vadim Dudkin, Jeffrey Kern, Izzat T. Raheem |
2015-06-23 |
$67,157,000 |
| 8993779 |
Positive allosteric modulators of MGLUR2 |
Vadim Dudkin, Mark E. Fraley, Kenneth L. Arrington, Alexander Joseph Reif, Kevin J. Rodzinak +1 more |
2015-03-31 |
$66,424,000 |
| 8952005 |
Substituted 1,3-benzothiazol-2(3H)-ones and [1,3]thiazolo[5,4-B]pyridin-2(1H)-ones as positive allosteric modulators of mGluR2 |
Michael J. Kelly, III |
2015-02-10 |
$89,040,000 |
| 8765784 |
Positive allosteric modulators of MGLUR2 |
Kenneth L. Arrington, Vadim Dudkin, Joseph E. Pero, Alexander Joseph Reif |
2014-07-01 |
$58,869,000 |
| 8536193 |
Inhibitors of AKT activity |
Hidetomo Furuyama, Yasuhiro Goto, Nobuhiko Kawanishi, Takashi Mita, Yoshio Ogino +5 more |
2013-09-17 |
$100,184,000 |
| 8481503 |
Combination cancer therapy with an AKT inhibitor and other anticancer agents |
Hiroshi Hirai, Hidehito Kotani |
2013-07-09 |
$144,918,000 |
| 8288407 |
Substituted naphthyridine compounds as inhibitors of Akt activity |
Michael J. Kelly, III, Philip E. Sanderson |
2012-10-16 |
$91,715,000 |
| 8207169 |
Substituted [1,2,4]triazolo[4′,3′:1,6]pyrido[2,3-b]pyrazines of the formula D |
Hidetomo Furuyama, Yasuhiro Goto, Nobuhiko Kawanishi, Takashi Mita, Akira Naya +6 more |
2012-06-26 |
|
| 8168652 |
Inhibitors of AKT activity |
Philip E. Sanderson, Kevin J. Rodzinak |
2012-05-01 |
$48,747,000 |
| 8008317 |
Inhibitors of akt activtiy |
Donna J. Armstrong, Essa Hu, Michael J. Kelly, III, Yiwei Li, Jun Liang +4 more |
2011-08-30 |
$42,029,000 |
