| 12492183 |
Tetrahydroquinazoline derivatives as selective cytotoxic agents |
Antonella Converso, David N. Hunter, Abdellatif El Marrouni, Anthony J. Roecker, Anthony W. Shaw +3 more |
2025-12-09 |
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| 12427159 |
Hydroxypyrrolidine-substituted arylsulfonamide compounds with selective activity in voltage-gated sodium channels |
Anthony J. Roecker, Mark E. Layton, Xiu Wang, Xuanjia Peng |
2025-09-30 |
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| 12246008 |
4-amino or 4-alkoxy-substituted aryl sulfonamide compounds with selective activity in voltage-gated sodium channels |
Christopher James Bungard, Helen Chen, Jason M. Cox, Liangqin Guo, Michael J. Kelly, III +9 more |
2025-03-11 |
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| 11066396 |
3-aryl- heteroaryl substituted 5-trifluoromethyl oxadiazoles as histonedeacetylase 6 (HDAC6) inhibitors |
Abbas M. Walji, Richard Berger, Craig A. Stump, Kelly-Ann S. Schlegel, James Mulhearn +3 more |
2021-07-20 |
$167,720,000 |
| 10968210 |
Diamino-alkylamino-linked arylsulfonamide compounds with selective activity in voltage-gated sodium channels |
Thomas J. Greshock, James Mulhearn, Anthony J. Roecker, Tianying Jian, Gang Zhou +9 more |
2021-04-06 |
$229,405,000 |
| 10577374 |
Bruton's tyrosine kinase inhibitors |
Minna Bui, Patrick R. Conlon, Julio H. Cuervo, Daniel Erlanson, Junfa Fan +11 more |
2020-03-03 |
$3,616,000 |
| 10519147 |
Diamino-alkylamino-linked arylsulfonamide compounds with selective activity in voltage-gated sodium channels |
Thomas J. Greshock, James Mulhearn, Liangqin Guo, Ting Zhang, Ronald Kim +8 more |
2019-12-31 |
$136,403,000 |
| 10421798 |
Factor VIII compositions and methods of making and using same |
Volker Schellenberger, Pei-Yun Chang, Fatbardha Varfaj, Sheng Ding, Joshua Silverman +10 more |
2019-09-24 |
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| 10285989 |
Pyrimidinone amide compounds as PDE2 inhibitors |
Dong-Ming Shen, Xiaoxia Qian, Bart Harper, Meng Yang, Yingjian Bo |
2019-05-14 |
$81,943,000 |
| 10287269 |
Pyrazolyl pyrimidinone compounds as PDE2 inhibitors |
Dong-Ming Shen, Jonathan E. Wilson, Meng Yang, Dann Parker, Zack Zhiqiang Guo +2 more |
2019-05-14 |
$81,943,000 |
| 10221167 |
Hydroxyalkylamine- and hydroxycycloalkylamine-substituted diamine-arylsulfonamide compounds with selective activity in voltage-gated sodium channels |
Thomas J. Greshock, James Mulhearn, Junying Zheng, Ronald Kim, Ting Zhang +6 more |
2019-03-05 |
$69,271,000 |
| 10174037 |
Dihydropyrazolopyrimidinone compounds as PDE2 inhibitors |
Dong-Ming Shen, Michael P. Dwyer, Christopher Joseph Sinz, Shawn J. Stachel, Daniel V. Paone +6 more |
2019-01-08 |
$185,104,000 |
| 10160762 |
6-alkyl dihydropyrazolopyrimidinone compounds as PDE2 inhibitors |
Dong-Ming Shen, Michael P. Dwyer, Christopher Joseph Sinz, Shawn J. Stachel, Daniel V. Paone +11 more |
2018-12-25 |
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| 10030016 |
Heterocyclic compounds useful as PDK1 inhibitors |
Joseph Arndt, Timothy Chan, Kevin M. Guckian, Gnanasambandam Kumaravel, Wen-Cherng Lee +7 more |
2018-07-24 |
$1,858,000 |
| 10017506 |
ATX modulating agents |
Kevin M. Guckian, Gnanasambandam Kumaravel, Bin Ma, Sha Mi, Hairuo Peng +5 more |
2018-07-10 |
$486,265,000 |
| 9815796 |
Pyrimidone carboxamide compounds as PDE2 inhibitors |
Dong-Ming Shen, Melissa Egbertson, Richard Berger, Xiaoxia Qian, Yimin Qian +9 more |
2017-11-14 |
$82,691,000 |
| 9790229 |
Bruton's tyrosine kinase inhibitors |
Minna Bui, Patrick R. Conlon, Julio H. Cuervo, Daniel Erlanson, Junfa Fan +11 more |
2017-10-17 |
$509,000 |
| 9555050 |
ATX modulating agents |
Kevin M. Guckian, Gnanasambandam Kumaravel, Bin Ma, Sha Mi, Zhaohui Shao +4 more |
2017-01-31 |
$458,474,000 |
| 9550783 |
Biaryl heterocyclic compounds and methods of making and using the same |
Jiacheng Zhou, Ashoke Bhattacharjee, Shili Chen, Yi Chen, Jay J. Farmer +9 more |
2017-01-24 |
$4,037,000 |
| 9546165 |
Heterocyclic compounds useful as PDK1 inhibitors |
Joseph Arndt, Timothy Chan, Kevin M. Guckian, Gnanasambandam Kumaravel, Wen-Cherng Lee +7 more |
2017-01-17 |
$1,415,000 |
| 9522889 |
ATX modulating agents |
Kevin M. Guckian, Gnanasambandam Kumaravel, Bin Ma, Sha Mi, Hairuo Peng +5 more |
2016-12-20 |
$230,911,000 |
| 9273028 |
Heterocyclic tyrosine kinase inhibitors |
Brian T. Hopkins, Daniel Scott, Patrick R. Conlon, Tracy J. Jenkins, Noel Powell +3 more |
2016-03-01 |
$486,730,000 |
| 9249146 |
Bruton'S tyrosine kinase inhibitors |
Minna Bui, Patrick R. Conlon, Julio H. Cuervo, Daniel Erlanson, Junfa Fan +11 more |
2016-02-02 |
$515,697,000 |
| 9029359 |
Heteroaryl Btk inhibitors |
Minna Bui, Patrick R. Conlon, Daniel Erlanson, Junfa Fan, Bing Guan +9 more |
2015-05-12 |
$4,096,000 |
| 8846671 |
Heterocyclic alkynyl benzene compounds and medical compositions and uses thereof |
Ke Ding, Duanqing Pei, Zhang Julia Zhang, Mengjie Shen, Kun Luo +1 more |
2014-09-30 |
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