| 10646494 |
Heterocycle-substituted tetracyclic compounds and methods of use thereof for the treatment of viral diseases |
Wensheng Yu, Ling Tong, Joseph A. Kozlowski, Craig A. Coburn, De-Yi Yang +7 more |
2020-05-12 |
$155,382,000 |
| 10357481 |
Substituted triazolo bicyclic compounds as PDE2 inhibitors |
Gregori J. Morriello, Lehua Chang, Ashley Forster, Yili Chen, Zack Zhiqiang Guo +4 more |
2019-07-23 |
$139,741,000 |
| 10287293 |
Bicyclic heterocyclic compounds as PDE2 inhibitors |
Shawn J. Stachel, Christopher Joseph Sinz, Jonathan E. Wilson, Daniel V. Paone, Yili Chen +1 more |
2019-05-14 |
$81,943,000 |
| 10174037 |
Dihydropyrazolopyrimidinone compounds as PDE2 inhibitors |
Dong-Ming Shen, Christopher Joseph Sinz, Deping Wang, Shawn J. Stachel, Daniel V. Paone +6 more |
2019-01-08 |
$185,104,000 |
| 10160762 |
6-alkyl dihydropyrazolopyrimidinone compounds as PDE2 inhibitors |
Dong-Ming Shen, Christopher Joseph Sinz, Deping Wang, Shawn J. Stachel, Daniel V. Paone +11 more |
2018-12-25 |
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| 10138255 |
Piperazine derivatives as HIV protease inhibitors |
Peter D. Williams, John A. McCauley, Christopher James Bungard, David Jonathan Bennett, Sherman T. Waddell +13 more |
2018-11-27 |
$94,550,000 |
| 9840478 |
Piperazine derivatives as HIV protease inhibitors |
Peter D. Williams, John A. McCauley, David Jonathan Bennett, Christopher James Bungard, Lehua Chang +17 more |
2017-12-12 |
$85,898,000 |
| 9254292 |
Fused tetracycle derivatives and methods of use thereof for the treatment of viral diseases |
Craig A. Coburn, Brian J. Lavey, Joseph A. Kozlowski, Stuart B. Rosenblum |
2016-02-09 |
$262,061,000 |
| 8987242 |
Morpholinone compounds as factor IXA inhibitors |
Samuel Chackalamannil, Tin-Yau Chan, Mariappan V. Chelliah, Martin C. Clasby, William J. Greenlee +6 more |
2015-03-24 |
$65,013,000 |
| 8673924 |
Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors |
Timothy J. Guzi, Kamil Paruch, Ronald J. Doll, Viyyoor M. Girijavallabhan, Alan K. Mallams +15 more |
2014-03-18 |
$46,244,000 |
| 8642582 |
Morpholinone compounds as factor IXa inhibitors |
Hidemitsu Nishida, Fumihiko Saitoh, Tomokazu Hirabayashi, Samuel Chackalamannil, Tin-Yau Chan +4 more |
2014-02-04 |
$91,639,000 |
| 8609676 |
4, 5, 6-trisubstituted pyrimidine derivatives as factor IXa inhibitors |
Mariappan V. Chelliah, Samuel Chackalamannil, William J. Greenlee, Keith Eagan, Zhuyan Guo +6 more |
2013-12-17 |
$54,459,000 |
| 8586576 |
Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors |
Timothy J. Guzi, Kamil Paruch, Marc A. Labroli, Kartik M. Keertikar |
2013-11-19 |
$50,784,000 |
| 8580782 |
Substituted pyrazolo[1,5-a]pyrimidines as cyclin dependent kinase inhibitors |
Timothy J. Guzi, Kamil Paruch, Marc A. Labroli, Kartik M. Keertikar |
2013-11-12 |
$66,896,000 |
| 8318735 |
2-aminothiazole-4-carboxylic amides as protein kinase inhibitors |
Gerald W. Shipps, Jr., Cliff C. Cheng, Xiaohua Huang, Thierry Olivier Fischmann, Jose S. Duca +12 more |
2012-11-27 |
$59,805,000 |
| 8211854 |
Methods for inhibiting protein kinases |
Timothy J. Guzi, Kamil Paruch, David A. Parry |
2012-07-03 |
|
| 8207221 |
Crystalline polymorphs of a CXC-chemokine receptor ligand |
Mengwei Hu, Younong Yu, Arthur G. Taveras, Agnes S. Kim-Meade, Jianguo Yin +4 more |
2012-06-26 |
|
| 7964646 |
3,4-DI-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
Arthur G. Taveras, Cynthia Aki, Richard Bond, Jianping Chao, Johan Ferreira +10 more |
2011-06-21 |
|
| 7947720 |
3,4-di-substituted cyclobutene-1,2-diones as CXC-chemokine receptor ligands |
Arthur G. Taveras, Cynthia Aki, Richard Bond, Jianping Chao, Johan Ferreira +9 more |
2011-05-24 |
|
| 7807683 |
N-heteroaryl pyrazolopyrimidines as cyclin dependent kinase inhibitors |
Timothy J. Guzi, Kamil Paruch, Ronald J. Doll, Viyyoor M. Girijavallabhan, Alan K. Mallams +13 more |
2010-10-05 |
|
| 7776865 |
Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors |
Kamil Paruch, Timothy J. Guzi, Carmen Alvarez |
2010-08-17 |
|
| 7645762 |
Substituted pyrazolo[1,5-a] pyrimidines as protein kinase inhibitors |
Kamil Paruch, Timothy J. Guzi |
2010-01-12 |
|
| 7642266 |
Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors |
Timothy J. Guzi, Kamil Paruch |
2010-01-05 |
|
| 7605155 |
Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors |
Timothy J. Guzi, Kamil Paruch, Marc A. Labroli, Kartik M. Keertikar |
2009-10-20 |
$142,962,000 |
| 7601724 |
Substituted pyrazolo[1,5-a]pyrimidines as protein kinase inhibitors |
Timothy J. Guzi, Kamil Paruch |
2009-10-13 |
$143,977,000 |
