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USPTO Patent Rankings Data through Dec 31, 2025
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Mark E. Fraley — 68 Patents

Merck: 70 patents #49 of 9,382Top 1%
North Wales, PA: #3 of 457 inventorsTop 1%
Pennsylvania: #364 of 74,527 inventorsTop 1%
Overall (All Time): #30,786 of 4,157,543Top 1%
68 Patents All Time
Mark E. Fraley has been granted 68 US patents while listed as an inventor at Merck. The first was granted in 1997 and the most recent in July 2021. Mark E. Fraley ranks #30,786 of 4,157,543 US inventors in our database (top 0.74%). Patent records list Mark E. Fraley in North Wales, PA, US.

Issued Patents All Time

Showing 1–25 of 68 patents

Patent #TitleCo-InventorsDateApprox Value ⓘ
11066396 3-aryl- heteroaryl substituted 5-trifluoromethyl oxadiazoles as histonedeacetylase 6 (HDAC6) inhibitors Abbas M. Walji, Richard Berger, Craig A. Stump, Kelly-Ann S. Schlegel, James Mulhearn +3 more 2021-07-20 $167,720,000
10272077 Piperidinone carboxamide azaindane CGRP receptor antagonists Ian M. Bell, Steven N. Gallicchio, Anthony Ginetti, Helen J. Mitchell, Daniel V. Paone +3 more 2019-04-30 $171,965,000
9914736 TrKA kinase inhibitors, compositions and methods thereof Helen J. Mitchell, Andrew Cooke, Craig A. Stump, Xu-Fang Zhang, Casey Cameron McComas +6 more 2018-03-13 $78,687,000
9862716 TRKA kinase inhibitors, compositions and methods thereof Helen J. Mitchell, Andrew Cooke, Craig A. Stump, Yi-Heng Chen, Xu-Fang Zhang +10 more 2018-01-09 $60,079,000
9833448 Piperidinone carboxamide azaindane CGRP receptor antagonists Ian M. Bell, Steven N. Gallicchio, Anthony Ginnetti, Helen J. Mitchell, Daniel V. Paone +3 more 2017-12-05 $49,639,000
9815846 TrkA kinase inhibitors, compositions and methods thereof Helen J. Mitchell, Andrew Cooke, Craig A. Stump, Yi-Heng Chen, Xu-Fang Zhang +13 more 2017-11-14 $82,691,000
9499545 Piperidinone carboxamide azaindane CGRP receptor antagonists Ian M. Bell, Steven N. Gallicchio, Anthony Ginnetti, Helen J. Mitchell, Daniel V. Paone +3 more 2016-11-22 $87,862,000
9499541 Piperidinone carboxamide indane CGRP receptor antagonists Ian M. Bell, Steven N. Gallicchio, Anthony Ginnetti, Helen J. Mitchell, Daniel V. Paone +4 more 2016-11-22 $87,862,000
9296750 Spirolactam CGRP receptor antagonists Ian M. Bell, Tesfaye Biftu, Cheng Zhu, Anilkumar G. Nair 2016-03-29 $130,981,000
9227972 Aliphatic spirolactam CGRP receptor antagonists Ian M. Bell, Tesfaye Biftu, Cheng Zhu, Anilkumar G. Nair, Helen J. Mitchell 2016-01-05 $74,452,000
9227973 Pyridine CGRP receptor antagonists Ian M. Bell, Tesfaye Biftu, Cheng Zhu, Anilkumar G. Nair 2016-01-05 $74,452,000
8993779 Positive allosteric modulators of MGLUR2 Vadim Dudkin, Kenneth L. Arrington, Mark E. Layton, Alexander Joseph Reif, Kevin J. Rodzinak +1 more 2015-03-31 $66,424,000
8975286 Ether benzotriazole derivatives Vadim Dudkin, Cheng Wang, Robert M. Garbaccio, Douglas C. Beshore, Scott K. Kuduk +1 more 2015-03-10 $87,534,000
8912210 Piperidinone carboxamide azaindane CGRP receptor antagonists Ian M. Bell, Steven N. Gallicchio, Anthony Ginnetti, Helen J. Mitchell, Daniel V. Paone +3 more 2014-12-16 $161,344,000
8883807 Piperidinone carboxamide indane CGRP receptor antagonists Ian M. Bell, Steven N. Gallicchio, Anthony Ginnetti, Helen J. Mitchell, Daniel V. Paone +4 more 2014-11-11 $48,775,000
8785481 Ether benzotriazole derivatives Douglas C. Beshore, Vadim Dudkin, Robert M. Garbaccio, Adam W. Johnson, Scott D. Kuduk +2 more 2014-07-22 $76,229,000
8754096 Piperidinone carboxamide azaindane CGRP receptor antagonists Ian M. Bell, Steven N. Gallicchio, Anthony Ginnetti, Helen J. Mitchell, Daniel V. Paone +4 more 2014-06-17 $87,270,000
8629275 AHCY hydrolase inhibitors for treatment of hyper homocysteinemia Antonella Converso, Timothy J. Hartingh 2014-01-14 $193,016,000
8623863 Disubstituted azepan orexin receptor antagonists Paul J. Coleman, John D. Schreier 2014-01-07 $63,301,000
8481556 Piperidinone carboxamide azaindane CGRP receptor antagonists Ian M. Bell 2013-07-09 $144,918,000
8329697 Imidizo[1,2-A]pyrazines useful as AHCY hydrolase inhibitors Robert M. Garbaccio, Antonella Converso, Timothy J. Hartingh 2012-12-11 $46,772,000
8063090 Mineralocorticoid receptor modulators Philip E. Brandish, James C. Hershey, Justin T. Steen 2011-11-22 $79,793,000
8003797 Pyridine carboxamide orexin receptor antagonists Jeffrey M. Bergman, Paul J. Coleman, Swati P. Mercer, Thomas S. Reger, Anthony J. Roecker +1 more 2011-08-23 $36,250,000
7732472 Mitotic kinesin inhibitors Robert M. Garbaccio, George D. Hartman 2010-06-08 $47,115,000
7723365 Mitotic kinesin inhibitors Christopher D. Cox, Robert M. Garbaccio 2010-05-25 $82,494,000