Issued Patents All Time
Showing 25 most recent of 47 patents
| Patent # | Title | Co-Inventors | Date |
|---|---|---|---|
| 12115154 | Compounds for the modulation of proprotein convertase subtilisin/kexin type 9 (PCSK9) | Simeon Bowers, Mark Karbarz, Jiang Zhu, Jonathan William Bourne, Anjali Pandey | 2024-10-15 |
| 11944619 | Phenylalanine small organic compounds to directly modulate PCSK9 protein activity | Jonathan William Bourne, Kyle D. Monroe, Michael M. Muehlemann, Anjali Pandey, Simeon Bowers | 2024-04-02 |
| 11945782 | Composition and methods of use of tetrahydroisoquinoline small molecules to bind and modulate PCSK9 protein activity | Jonathan William Bourne, Kyle D. Monroe, Michael M. Muehlemann, Anjali Pandey, Simeon Bowers | 2024-04-02 |
| 11925637 | Phenylpiperazine proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators and their use | Jonathan William Bourne, Kyle D. Monroe, Michael M. Muehlemann, Anjali Pandey, Simeon Bowers | 2024-03-12 |
| 11891369 | Compounds for binding proprotein convertase subtilisin/kexin type 9 | Anjali Pandey, Simeon Bowers, Jonathan William Bourne | 2024-02-06 |
| 11771710 | Method to treat lipid dysregulation by modulation of proprotein convertase subtilisin/kexin type 9 (PCSK9) protein activity with small molecule ligands | Jonathan William Bourne, Kyle D. Monroe, Michael M. Muehlemann | 2023-10-03 |
| 11026957 | Method to treat lipid dysregulation by modulation of proprotein convertase subtilisin/kexin type 9 (PCSK9) protein activity with small molecule ligands | Jonathan William Bourne, Kyle D. Monroe, Michael M. Muehlemann | 2021-06-08 |
| 10980801 | Phenylpiperazine proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators and their use | Jonathan William Bourne, Kyle D. Monroe, Michael M. Muehlemann, Anjali Pandey, Simeon Bowers | 2021-04-20 |
| 10865185 | Composition and methods of use of tetrahydroisoquinoline small molecules to bind and modulate PCSK9 protein activity | Jonathan William Bourne, Kyle D. Monroe, Michael M. Muehlemann, Anjali Pandey, Simeon Bowers | 2020-12-15 |
| 10821106 | Composition and methods of use of novel phenylalanine small organic compounds to directly modulate PCSK9 protein activity | Jonathan William Bourne, Kyle D. Monroe, Michael M. Muehlemann, Anjali Pandey, Simeon Bowers | 2020-11-03 |
| 10688114 | Composition and methods of use of small molecules as binding ligands for the modulation of proprotein convertase subtilisin/kexin type 9(PCSK9) protein activity | Jonathan William Bourne, Kyle D. Monroe, Michael M. Muehlemann | 2020-06-23 |
| 10568882 | Phenylpiperazine proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators and their use | Jonathan William Bourne, Kyle D. Monroe, Michael M. Muehlemann, Anjali Pandey, Simeon Bowers | 2020-02-25 |
| 10307433 | Composition and methods of use of small molecules as binding ligands for the modulation of proprotein convertase subtilisin/kexin type 9(PCSK9) protein activity | Jonathan William Bourne, Kyle D. Monroe, Michael M. Muehlemann | 2019-06-04 |
| 10287317 | Proprotein convertase subtilisin kexin type 9 (PCSK9) allosteric binding ligands to modulate serum low density lipoprotein (LDL) levels | Michael M. Muehlemann, Kyle D. Monroe, Jonathan William Bourne, Margaret Thompson Reece, Vesa Nevalainen +1 more | 2019-05-14 |
| 10034892 | Composition and methods of use of small molecules as binding ligands for the modulation of proprotein convertase subtilisin/kexin type 9(PCSK9) protein activity | Jonathan William Bourne, Kyle D. Monroe, Michael M. Muehlemann | 2018-07-31 |
| 9656956 | Benzene, pyridine, and pyridazine derivatives | Kenneth He Huang, Jeron Eaves, Gunnar J. Hanson, James Marvin Veal, Lifeng Geng +1 more | 2017-05-23 |
| 8309548 | Benzene, pyridine, and pyridazine derivatives | Kenneth He Huang, Jeron Eaves, Gunnar J. Hanson, James Marvin Veal, Lifeng Geng +1 more | 2012-11-13 |
| 7928135 | Benzene, pyridine, and pyridazine derivatives | Kenneth He Huang, Jeron Eaves, Gunnar J. Hanson, James Marvin Veal, Lifeng Geng +1 more | 2011-04-19 |
| 7906529 | Benzene, pyridine, and pyridazine derivatives | Kenneth He Huang, Jeron Eaves, Gunnar J. Hanson, James Marvin Veal, Lifeng Geng +1 more | 2011-03-15 |
| 7678803 | Quinazoline derivatives for the treatment of cancer | Kenneth He Huang, James Marvin Veal, Emilie Smith, Wei Ma, Andy J. Ommen | 2010-03-16 |
| 7358370 | Benzene, pyridine, and pyridazine derivatives | Kenneth He Huang, Jeron Eaves, Gunnar J. Hanson, James Marvin Veal, Lifeng Geng +1 more | 2008-04-15 |
| 7282506 | 2,8-disubstituted naphthyridine derivatives | Gunnar J. Hanson, Roy W. Ware, He Huang | 2007-10-16 |
| 7119203 | Piperidinyl- and piperazinyl-sulfonylmethyl hydroxamic acids and their use as protease inhibitors | Daniel P. Becker, Louis Bedell, Terri Boehm, David L. Brown, Jeffery Carroll +25 more | 2006-10-10 |
| 7115632 | Sulfonyl aryl or heteroaryl hydroxamic acid compounds | Louis Bedell, Joseph McDonald, Daniel P. Becker, Rao N Shashidhar, John N. Freskos +4 more | 2006-10-03 |
| 6890928 | Aromatic sulfone hydroxamic acids and their use as protease inhibitors | John N. Freskos, Yvette M. Fobian, Daniel P. Becker, Louis Bedell, Terri Boehm +12 more | 2005-05-10 |