| 12115154 |
Compounds for the modulation of proprotein convertase subtilisin/kexin type 9 (PCSK9) |
Simeon Bowers, Mark Karbarz, Jiang Zhu, Thomas E. Barta, Anjali Pandey |
2024-10-15 |
| 11944619 |
Phenylalanine small organic compounds to directly modulate PCSK9 protein activity |
Thomas E. Barta, Kyle D. Monroe, Michael M. Muehlemann, Anjali Pandey, Simeon Bowers |
2024-04-02 |
| 11945782 |
Composition and methods of use of tetrahydroisoquinoline small molecules to bind and modulate PCSK9 protein activity |
Thomas E. Barta, Kyle D. Monroe, Michael M. Muehlemann, Anjali Pandey, Simeon Bowers |
2024-04-02 |
| 11925637 |
Phenylpiperazine proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators and their use |
Thomas E. Barta, Kyle D. Monroe, Michael M. Muehlemann, Anjali Pandey, Simeon Bowers |
2024-03-12 |
| 11891369 |
Compounds for binding proprotein convertase subtilisin/kexin type 9 |
Anjali Pandey, Simeon Bowers, Thomas E. Barta |
2024-02-06 |
| 11771710 |
Method to treat lipid dysregulation by modulation of proprotein convertase subtilisin/kexin type 9 (PCSK9) protein activity with small molecule ligands |
Thomas E. Barta, Kyle D. Monroe, Michael M. Muehlemann |
2023-10-03 |
| 11026957 |
Method to treat lipid dysregulation by modulation of proprotein convertase subtilisin/kexin type 9 (PCSK9) protein activity with small molecule ligands |
Thomas E. Barta, Kyle D. Monroe, Michael M. Muehlemann |
2021-06-08 |
| 10980801 |
Phenylpiperazine proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators and their use |
Thomas E. Barta, Kyle D. Monroe, Michael M. Muehlemann, Anjali Pandey, Simeon Bowers |
2021-04-20 |
| 10865185 |
Composition and methods of use of tetrahydroisoquinoline small molecules to bind and modulate PCSK9 protein activity |
Thomas E. Barta, Kyle D. Monroe, Michael M. Muehlemann, Anjali Pandey, Simeon Bowers |
2020-12-15 |
| 10821106 |
Composition and methods of use of novel phenylalanine small organic compounds to directly modulate PCSK9 protein activity |
Thomas E. Barta, Kyle D. Monroe, Michael M. Muehlemann, Anjali Pandey, Simeon Bowers |
2020-11-03 |
| 10688114 |
Composition and methods of use of small molecules as binding ligands for the modulation of proprotein convertase subtilisin/kexin type 9(PCSK9) protein activity |
Thomas E. Barta, Kyle D. Monroe, Michael M. Muehlemann |
2020-06-23 |
| 10568882 |
Phenylpiperazine proprotein convertase subtilisin/kexin type 9 (PCSK9) modulators and their use |
Thomas E. Barta, Kyle D. Monroe, Michael M. Muehlemann, Anjali Pandey, Simeon Bowers |
2020-02-25 |
| 10307433 |
Composition and methods of use of small molecules as binding ligands for the modulation of proprotein convertase subtilisin/kexin type 9(PCSK9) protein activity |
Thomas E. Barta, Kyle D. Monroe, Michael M. Muehlemann |
2019-06-04 |
| 10287317 |
Proprotein convertase subtilisin kexin type 9 (PCSK9) allosteric binding ligands to modulate serum low density lipoprotein (LDL) levels |
Michael M. Muehlemann, Thomas E. Barta, Kyle D. Monroe, Margaret Thompson Reece, Vesa Nevalainen +1 more |
2019-05-14 |
| 10034892 |
Composition and methods of use of small molecules as binding ligands for the modulation of proprotein convertase subtilisin/kexin type 9(PCSK9) protein activity |
Thomas E. Barta, Kyle D. Monroe, Michael M. Muehlemann |
2018-07-31 |
| 9309304 |
Glycation cross-link breakers to increase resistance to enzymatic degradation |
Peter Torzilli |
2016-04-12 |