| 9301929 |
Substituted biaryl derivatives and methods of use thereof |
Claire M. Lankin, William J. Greenlee, Joel M. Harris |
2016-04-05 |
$208,910,000 |
| 9161924 |
Factor IXa inhibitors |
William J. Greenlee, Samuel Chackalamannil, Claire M. Lankin |
2015-10-20 |
$195,645,000 |
| 8907095 |
Bicyclic heterocycle derivatives and their use as modulators of the activity of GPR119 |
Yan Xia, William J. Greenlee, Samuel Chackalamannil, Charles Lee Jayne |
2014-12-09 |
$45,770,000 |
| 8822480 |
Bicyclic heterocycle derivatives and use thereof as GPR119 modulators |
Santhosh F. Neelamkavil, Samuel Chackalamannil, William J. Greenlee, Bernard R. Neustadt, Andrew Stamford |
2014-09-02 |
$81,033,000 |
| 8815876 |
Bicyclic heterocycle derivatives and methods of use thereof |
Santhosh F. Neelamkavil, Bernard R. Neustadt, Samuel Chackalamannil, William J. Greenlee |
2014-08-26 |
$59,520,000 |
| 8604195 |
Substituted bicyclic piperidinyl- and piperazinyl-sulfonamides useful to inhibit 11β-hydroxysteroid dehydrogenase type-1 |
Unmesh Shah, Samuel Chackalamannil |
2013-12-10 |
$69,974,000 |
| 8580807 |
Bicyclic piperidine and piperazine derivatives as GPCR modulators for the treatment of obesity, diabetes and other metabolic disorders |
Claire M. Lankin, Unmesh Shah, William J. Greenlee, Samuel Chackalamannil |
2013-11-12 |
$66,896,000 |
| 8466149 |
6-substituted sulfonyl azabicyclo[3.2.1]octanes useful to inhibit 11β-hydroxysteroid dehydrogenase type-I |
Samuel Chackalamannil, Unmesh Shah, Claire M. Lankin |
2013-06-18 |
$99,229,000 |
| RE44205 |
Adenosine A2a receptor antagonists |
Bernard R. Neustadt, Neil A. Lindo, William J. Greenlee, Deen Tulshian, Lisa S. Silverman +2 more |
2013-05-07 |
|
| 8389532 |
7-[2-[4-(6-fluoro-3-methyl-1,2-benzisoxazol-5-yl)-1-piperazinyl]ethyl]-2-(1-propynyl)-7H-pyrazolo-[4,3-E]-[1,2,4]-triazolo-[1,5-C]-pyrimidin-5-amine |
Samuel Chackalamannil, Unmesh Shah, Jean E. Lachowicz |
2013-03-05 |
$77,218,000 |
| 8318751 |
Pyrimidinone derivatives and methods of use thereof |
Samuel Chackalamannil, Claire M. Lankin, Unmesh Shah, Bernard R. Neustadt, Hong Liu +1 more |
2012-11-27 |
$59,805,000 |
| 7709492 |
Pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists |
Bernard R. Neustadt, Jinsong Hao, Hong Liu, Samuel Chackalamannil, Unmesh Shah +2 more |
2010-05-04 |
|
| 7572802 |
7-[2-[4-(6-fluoro-3-methyl-1,2-benzisoxazol-5-yl)-1-piperazinyl]ethyl]-2-(1-propynyl)-7H-pyrazolo-[4,3-e]-[1,2,4]-triazolo-[1,5-C]-pyrimidin-5-amine |
Samuel Chackalamannil, Unmesh Shah, Jean E. Lachowicz |
2009-08-11 |
$207,663,000 |
| 7531544 |
Xanthine phosphodiesterase V inhibitors |
Samuel Chackalamannil, Yuguang Wang, Andrew Stamford |
2009-05-12 |
$208,740,000 |
| 7465740 |
2-heteroaryl-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists |
Bernard R. Neustadt, Samuel Chackalamannil, Joel M. Harris, Claire M. Lankin, Hong Liu +2 more |
2008-12-16 |
$107,689,000 |
| 7368449 |
2-alkynyl- and 2-alkenyl-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists |
Bernard R. Neustadt, Jinsong Hao, Hong Liu, Samuel Chackalamannil, Unmesh Shah +1 more |
2008-05-06 |
$81,187,000 |
| 7312223 |
Metabolite of xanthine Phosphodiesterase 5 inhibitor and derivatives thereof useful for treatment of erectile dysfunction |
Anima Ghosal, Wei Tong, Swapan Chowdhury, Shmuel Zbaida, Mark A. Wirth +3 more |
2007-12-25 |
|
| 7268141 |
Xanthine phosphodiesterase V inhibitors |
Samuel Chackalamannil, Yuguang Wang, Andrew Stamford |
2007-09-11 |
$105,277,000 |
| 7192962 |
Xanthine phosphodiesterase V inhibitor polymorphs |
Vilas Hareshwar Dahanukar, Hoa N. Nguyen, Cecilia Orr, Funcheng Zhang, Ilia Zavialov +3 more |
2007-03-20 |
$49,693,000 |
| 6916811 |
Adenosine A2a receptor antagonists |
Samuel Chackalamannil, William J. Greenlee, Unmesh Shah, Yan Xia |
2005-07-12 |
$87,141,000 |
| 6897217 |
2-Alkynyl-and 2-alkenyl-pyrazolo-[4,3-e]-1,2,4-triazolo-[1,5-c]-pyrimidine adenosine A2a receptor antagonists |
Bernard R. Neustadt, Jinsong Hao, Hong Liu, Samuel Chackalamannil, Unmesh Shah +1 more |
2005-05-24 |
$82,497,000 |
| 6897216 |
Adenosine A2a receptor antagonists |
Bernard R. Neustadt, Neil A. Lindo, William J. Greenlee, Deen Tulshian, Lisa S. Silverman +2 more |
2005-05-24 |
$82,497,000 |
| 6890936 |
Muscarinic antagonists |
William J. Greenlee, Samuel Chackalamannil |
2005-05-10 |
$89,005,000 |
| 6821978 |
Xanthine phosphodiesterase V inhibitors |
Samuel Chackalamannil, Yuguang Wang, Andrew Stamford |
2004-11-23 |
$134,374,000 |
| 6632828 |
Substituted imidazole neuropeptide Y Y5 receptor antagonists |
Andrew Stamford, Ying Huang |
2003-10-14 |
$44,282,000 |
