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Pyridine rings containing derivatives as MALT1 inhibitors |
Johannes Wilhelmus John F. Thuring, Tianbao Lu, Tongfei Wu, Gaston Stanislas Marcella Diels, Berthold Wroblowski |
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Pyrazole derivatives as MALT1 inhibitors |
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(R)-8-(1-((3-fluorophenyl)amino)ethyl)-N-(2-hydroxyethyl)-2-morpholinoquinoxaline-6-carboxamide for inhibiting phosphoinositide-3-kinase activity |
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2022-03-08 |
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Quinoxaline and pyridopyrazine derivatives as PI3K-beta inhibitors |
Patrick René Angibaud, Olivier Alexis Georges Querolle, Christophe Meyer, Matthieu WILLOT, Lieven Meerpoel +1 more |
2021-09-28 |
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Pyrazole derivatives as MALT1 inhibitors |
Tianbao Lu, Brett D. Allison, Joseph Kent Barbay, Peter J. Connolly, Maxwell D. Cummings +7 more |
2021-03-23 |
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Substituted nucleoside analogues for use as PRMT5 inhibitors |
Dirk Brehmer, Lijs Beke, An Boeckx, Gaston Stanislas Marcella Diels, Ronaldus Arnodus Hendrika Joseph Gilissen +10 more |
2021-01-26 |
| 10894793 |
Bicyclic pyridine, pyrazine, and pyrimidine derivatives as PI3K beta inhibitors |
Laurence Anne Mevellec, Patrick René Angibaud, Sophie Coupa, Christophe Gabriel Marcel Demestre, Lieven Meerpoel +6 more |
2021-01-19 |
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Pyrazole derivatives as MALT1 inhibitors |
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2021-01-12 |
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Quinoxaline and pyridopyrazine derivatives as PI3Kβ inhibitors |
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2020-01-07 |
| 10202387 |
Heterocyclyl linked imidazopyridazine derivatives as PI3KB inhibitors |
Laurence Anne Mevellec, Lieven Meerpoel, Sophie Coupa, Virginie Sophie Poncelet, Isabelle Noëlle Constance Pilatte +6 more |
2019-02-12 |
| 10087187 |
Imidazopyridazine derivatives as PI3KB inhibitors |
Laurence Anne Mevellec, Lieven Meerpoel, Sophie Coupa, Virginie Sophie Poncelet, Isabelle Noëlle Constance Pilatte +6 more |
2018-10-02 |
| 10017509 |
Macrocylic pyrimidine derivatives |
Gaston Stanislas Marcella Diels, Bruno Schoentjes, Matthias VERSELE, Marc Willems, Marcel Viellevoye +3 more |
2018-07-10 |
| 9145399 |
Substituted bicyclic triazole derivatives as gamma secretase modulators |
Michel Anna Jozef De Cleyn, Sven Franciscus Anna Van Brandt, Henricus Jacobus Maria Gijsen, Daniel Oehlrich |
2015-09-29 |
| 9115143 |
Substituted indole derivatives as gamma secretase modulators |
Garrett Berlond Minne, François Paul Bischoff, Henricus Jacobus Maria Gijsen, Adriana Ingrid Velter, Serge Maria Aloysius Pieters |
2015-08-25 |
| 9079886 |
Substituted triazole derivatives as gamma secretase modulators |
Sven Franciscus Anna Van Brandt, Michel Anna Jozef De Cleyn, Henricus Jacobus Maria Gijsen, Michel Surkyn |
2015-07-14 |
| 8987276 |
Substituted triazolyl piperazine and triazolyl piperidine derivatives as gamma secretase modulators |
François Paul Bischoff, Adriana Ingrid Velter, Sven Franciscus Anna Van Brandt |
2015-03-24 |
| 8946266 |
Substituted triazole and imidazole derivatives as gamma secretase modulators |
Tongfei Wu, Henricus Jacobus Maria Gijsen, Frederik Jan Rita Rombouts, François Paul Bischoff, Daniel Oehlrich +6 more |
2015-02-03 |
| 8946426 |
Substituted bicyclic heterocyclic compounds as gamma secretase modulators |
Henricus Jacobus Maria Gijsen, Adriana Ingrid Velter, Gregor James MacDonald, François Paul Bischoff, Tongfei Wu +6 more |
2015-02-03 |
| 8772504 |
Substituted benzoxazole, benzimidazole, oxazolopyridine and imidazopyridine derivatives as gamma secretase modulators |
Henricus Jacobus Maria Gijsen, François Paul Bischoff, Wei Zhuang, Sven Franciscus Anna Van Brandt, Michel Surkyn +4 more |
2014-07-08 |
| 8614201 |
Heterocyclic amides as modulators of TRPA1 |
Henricus Jacobus Maria Gijsen, Mirko Zaja, Jason C. Rech, Alec D. Lebsack, Bryan James Branstetter +2 more |
2013-12-24 |
| 8546440 |
Substituted bicyclic imidazole derivatives as gamma secretase modulators |
Henricus Jacobus Maria Gijsen, Gregor James MacDonald, François Paul Bischoff, Gary John Tresadern, Andrés Avelino Trabanco-Suárez +1 more |
2013-10-01 |
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2-amino-quinazoline derivatives useful as inhibitors of β-secretase (BACE) |
François Paul Bischoff, Mirielle Braeken, Serge Maria Aloysius Pieters, Mark Hubert Mercken, Hans Louis Jos De Winter |
2013-05-07 |
| 8263592 |
Equilibrative nucleoside transporter ENT1 inhibitors |
Jean-Paul René Marie André Bosmans, Serge Maria Aloysius Pieters, Bie Maria Pieter Verbist, Michel Anna Jozef De Cleyn |
2012-09-11 |
| 8114880 |
Piperidine or piperazine substituted tetrahydro-naphthalene-1-carboxylic acid MTP inhibiting compounds |
Lieven Meerpoel, Joannes Theodorus Maria Linders, Libuse Jaroskova, Marcel Viellevoye, Leo Jacobus Jozef Backx +1 more |
2012-02-14 |