Issued Patents All Time
Showing 1–25 of 54 patents
| Patent # | Title | Co-Inventors | Date |
|---|---|---|---|
| 12048696 | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use | Brian D. KLEIN, Hilde Lavreysen, Stefan Maria Christiaan Pype, Roy E. Twyman, Nancy Eulalie Sylvain Van Osselaer +3 more | 2024-07-30 |
| 11369606 | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use | Brian D. KLEIN, Hilde Lavreysen, Stefan Maria Christiaan Pype, Roy E. Twyman, Nancy Eulalie Sylvain Van Osselaer +4 more | 2022-06-28 |
| 11103506 | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use | Brian D. KLEIN, Hilde Lavreysen, Stefan Maria Christiaan Pype, Roy E. Twyman, Nancy Eulalie Sylvain Van Osselaer +3 more | 2021-08-31 |
| 11071729 | 1′,3′-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2H,1′H-[1,4′]bipyridinyl-2′-ones | Jose Maria Cid-Nunez, Gregor James MacDonald, Guillaume Albert Jacques Duvey, Terry Patrick Finn | 2021-07-27 |
| 10604523 | 1-aryl-4-methyl-[1,2,4]triazolo[4,3-a]quinoxaline derivatives | José Ignacio Andrés-Gil, Peter Jacobus Johannes Antonius Buijnsters, Meri De Angelis, Greta Constantia Peter Vanhoof, Jérôme Emile Georges Guillemont +4 more | 2020-03-31 |
| 10584129 | Substituted 6,7-dihydropyrazolo[1,5-a]pyrazines as negative allosteric modulators of mGluR2 receptors | Sergio-Alvar Alonso-de Diego, Jose Maria Cid-Nunez, Óscar Delgado-González, Annelies Marie Antonius Decorte, Michiel Luc Maria Van Gool +4 more | 2020-03-10 |
| 10537573 | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use | Brian D. KLEIN, Hilde Lavreysen, Stefan Maria Christiaan Pype, Roy E. Twyman, Nancy Eulalie Sylvain Van Osselaer +4 more | 2020-01-21 |
| 10519162 | 6,7-dihydropyrazolo[1,5-α]pyrazin-4(5H)-one compounds and their use as negative allosteric modulators of mGluR2 receptors | Sergio-Alvar Alonso-de Diego, Michiel Luc Maria Van Gool, María Luz Martín-Martín, Susana Conde-Ceide, José Ignacio Andrés-Gil +2 more | 2019-12-31 |
| 10512646 | Substituted 6,7-dihydropyrazolo[1,5-a]pyrazines as negative allosteric modulators of mGluR2 receptors | Sergio-Alvar Alonso-de Diego, Michiel Luc Maria Van Gool, Óscar Delgado-González, José Ignacio Andrés-Gil | 2019-12-24 |
| 10112949 | 6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one compounds and their use as negative allosteric modulators of mGluR2 receptors | José Ignacio Andrés-Gil, Michiel Luc Maria Van Gool, Ana Isabel De Lucas Olivares, Sergio-Alvar Alonso-de Diego, Óscar Delgado-González | 2018-10-30 |
| 10106542 | Substituted 6,7-dihydropyrazolo[1,5-a]pyrazines as negative allosteric modulators of mGluR2 receptors | Sergio-Alvar Alonso-de Diego, Jose Maria Cid-Nunez, Óscar Delgado-González, Annelies Marie Antonius Decorte, Michiel Luc Maria Van Gool +4 more | 2018-10-23 |
| 10106524 | 2,3,4,5-tetrahydropyridin-6-amine and 3,4-dihydro-2H-pyrrol-5-amine compound inhibitors of beta-secretase | Óscar Delgado-González, Henricus Jacobus Maria Gijsen, Michiel Luc Maria Van Gool, Sven Franciscus Anna Van Brandt, Michel Anna Jozef De Cleyn +2 more | 2018-10-23 |
| 10071095 | 1,2,4-triazolo [4,3-A] pyridine derivatives and their use for the treatment of neurological and psychiatric disorders | Jose Maria Cid-Nunez, Daniel Oehlrich, Gary John Tresadern, Juan Antonio Vega Ramiro, Gregor James MacDonold | 2018-09-11 |
| 10005785 | Substituted 6,7-dihydropyrazolo[1,5-a] pyrazines as negative allosteric modulators of mGlUR2 receptors | Sergio-Alvar Alonso-de Diego, Michiel Luc Maria Van Gool, María Luz Martín-Martín, Susana Conde-Ceide, José Ignacio Andrés-Gil +2 more | 2018-06-26 |
| 10005786 | Substituted 6,7-dihydropyrazolo[1,5-a]pyrazines as negative allosteric modulators of MGLUR2 receptors | Sergio-Alvar Alonso-de Diego, Michiel Luc Maria Van Gool, Óscar Delgado-González, José Ignacio Andrés-Gil | 2018-06-26 |
| 9845326 | Substituted 3,4-dihydropyrrolo[1,2-A]pyrazines as beta-secretase (BACE) inhibitors | Francisca Delgado-Jiménez | 2017-12-19 |
| 9840507 | 5,6-dihydro-imidazo[1,2-a]pyrazin-8-ylamine derivatives useful as inhibitors of beta-secretase (BACE) | Francisca Delgado-Jiménez, Juan Antonio Vega Ramiro, Gary John Tresadern, Henricus Jacobus Maria Gijsen, Daniel Oehlrich | 2017-12-12 |
| 9828350 | 5,6-dihydro-2H-[1,4]oxazin-3-yl-amine derivatives useful as inhibitors of beta-secretase (BACE) | Frederik Jan Rita Rombouts, Gary John Tresadern, Michiel Luc Maria Van Gool, Gregor James MacDonald, Carolina Martinez Lamenca +1 more | 2017-11-28 |
| 9737533 | 1,2,4-triazolo [4,3-A] pyridine derivatives and their use for the treatment of prevention of neurological and psychiatric disorders | Jose Maria Cid-Nunez, Daniel Oehlrich, Gary John Tresadern, Juan Antonio Vega Ramiro, Gregor James MacDonald | 2017-08-22 |
| 9708315 | 1,2,4-triazolo[4,3-a]pyridine compounds and their use as positive allosteric modulators of MGLUR2 receptors | Jose Maria Cid-Nunez, Marc André Ceusters, Hilde Lavreysen | 2017-07-18 |
| 9346811 | 6,7-dihydro-pyrazolo[1,5-a]pyrazin-4-ylamine derivatives useful as inhibitors of beta-secretase (BACE) | Henricus Jacobus Maria Gijsen, Michiel Luc Maria Van Gool, Juan Antonio Vega Ramiro, Francisca Delgado-Jiménez | 2016-05-24 |
| 9271967 | 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mGluR2 receptors | Jose Maria Cid-Nunez, Juan Antonio Vega Ramiro, Daniel Oehlrich, Gary John Tresadern, Gregor James MacDonald | 2016-03-01 |
| 9266834 | 1, 4-disubstituted 3-cyano-pyridone derivatives and their use as positive allosteric modulators of MGLUR2-receptors | Hassan Imogai, Jose Maria Cid-Nunez, José Ignacio Andrés-Gil, Julen OYARZABAL SANTAMARINA, Frank Matthias Dautzenberg +7 more | 2016-02-23 |
| 9226930 | 1,2,4-triazolo [4,3-a] pyridine derivatives and their use for the treatment of prevention of neurological and psychiatric disorders | Jose Maria Cid-Nunez, Daniel Oehlrich, Gary John Tresadern, Juan Antonio Vega Ramiro, Gregor James MacDonald | 2016-01-05 |
| 9181245 | Substituted pyrido[1,2-a]pyrazines and substituted pyrido[1,2-a][1,4]diazepines for the treatment of (inter alia) Alzheimer's disease | Frederik Jan Rita Rombouts, Henricus Jacobus Maria Gijsen, Gregor James MacDonald, François Paul Bischoff, Sergio-Alvar Alonso-de-Diego +2 more | 2015-11-10 |