| 12084462 |
Spiro bicyclic inhibitors of menin-MLL interaction |
Vineet Pande, Barbara Herkert, Daniel Jason Krosky, Olivier Alexis Georges Querolle, Aaron Nathaniel Patrick +1 more |
2024-09-10 |
$185,485,000 |
| 11542247 |
Bi-heteroaryl substitute 1,4-benzodiazepines and uses thereof for the treatment of cancer |
Diego Broggini, Filip Albert C Cuyckens, Steven Anna Hostyn, Russell Mark Jones, Olivier Alexis Georges Querolle +1 more |
2023-01-03 |
$346,989,000 |
| 11530226 |
Azepane inhibitors of menin-MLL interaction |
Vineet Pande, Barbara Herkert, Daniel Jason Krosky, Olivier Alexis Georges Querolle, Aaron Nathaniel Patrick +1 more |
2022-12-20 |
$538,765,000 |
| 11396517 |
Exo-aza spiro inhibitors of menin-MLL interaction |
Xuedong Dai, Olivier Alexis Georges Querolle, Daniel Jason Krosky, Wei CAI, Liqiang FU +8 more |
2022-07-26 |
$1,169,316,000 |
| 11267804 |
(R)-8-(1-((3-fluorophenyl)amino)ethyl)-N-(2-hydroxyethyl)-2-morpholinoquinoxaline-6-carboxamide for inhibiting phosphoinositide-3-kinase activity |
Olivier Alexis Georges Querolle, Didier Jean-Claude Berthelot, Christophe Meyer, Matthieu WILLOT, Lieven Meerpoel +1 more |
2022-03-08 |
$372,209,000 |
| 11220517 |
Spiro bicyclic inhibitors of menin-MLL interaction |
Vineet Pande, Barbara Herkert, Daniel Jason Krosky, Olivier Alexis Georges Querolle, Aaron Nathaniel Patrick +1 more |
2022-01-11 |
$249,880,000 |
| 11155555 |
Compounds |
Diego Broggini, Helene France Solange Colombel, Filip Albert C Cuyckens, Steven Anna Hostyn, Russell Mark Jones +2 more |
2021-10-26 |
$230,543,000 |
| 11130751 |
Quinoxaline and pyridopyrazine derivatives as PI3K-beta inhibitors |
Olivier Alexis Georges Querolle, Didier Jean-Claude Berthelot, Christophe Meyer, Matthieu WILLOT, Lieven Meerpoel +1 more |
2021-09-28 |
$293,549,000 |
| 10975100 |
Fused bicyclic inhibitors of menin-MLL interaction |
Vineet Pande, Barbara Herkert, Daniel Jason Krosky, Olivier Alexis Georges Querolle, Aaron Nathaniel Patrick |
2021-04-13 |
$63,321,000 |
| 10894793 |
Bicyclic pyridine, pyrazine, and pyrimidine derivatives as PI3K beta inhibitors |
Didier Jean-Claude Berthelot, Laurence Anne Mevellec, Sophie Coupa, Christophe Gabriel Marcel Demestre, Lieven Meerpoel +6 more |
2021-01-19 |
$146,074,000 |
| 10745409 |
Azepane inhibitors of menin-MLL interaction |
Vineet Pande, Barbara Herkert, Daniel Jason Krosky, Olivier Alexis Georges Querolle, Aaron Nathaniel Patrick +1 more |
2020-08-18 |
$101,666,000 |
| 10611778 |
Fused bicyclic inhibitors of menin-MLL interaction |
Vineet Pande, Barbara Herkert, Daniel Jason Krosky, Olivier Alexis Georges Querolle, Aaron Nathaniel Patrick |
2020-04-07 |
$165,837,000 |
| 10526316 |
Quinoxaline and pyridopyrazine derivatives as PI3Kβ inhibitors |
Olivier Alexis Georges Querolle, Didier Jean-Claude Berthelot, Christophe Meyer, Matthieu WILLOT, Lieven Meerpoel +1 more |
2020-01-07 |
$77,223,000 |
| 10519137 |
Pyrazolyl quinoxaline kinase inhibitors |
Gordon Saxty, Christopher William Murray, Valerio Berdini, Gilbert Ebai Besong, Steven John Woodhead +12 more |
2019-12-31 |
|
| 10272087 |
Pteridines as FGFR inhibitors |
Gordon Saxty, Christopher Charles Frederick Hamlett, Valerio Berdini, Christopher William Murray, Olivier Alexis Georges Querolle +1 more |
2019-04-30 |
|
| 10202387 |
Heterocyclyl linked imidazopyridazine derivatives as PI3KB inhibitors |
Laurence Anne Mevellec, Lieven Meerpoel, Sophie Coupa, Virginie Sophie Poncelet, Isabelle Noëlle Constance Pilatte +6 more |
2019-02-12 |
$117,769,000 |
| 10087187 |
Imidazopyridazine derivatives as PI3KB inhibitors |
Laurence Anne Mevellec, Lieven Meerpoel, Sophie Coupa, Virginie Sophie Poncelet, Isabelle Noëlle Constance Pilatte +6 more |
2018-10-02 |
$95,730,000 |
| 10045982 |
Substituted pyrido[2,3-b]pyrazines as FGFR kinase inhibitors |
Valerio Berdini, Gordon Saxty, Olivier Alexis Georges Querolle, Virginie Sophie Poncelet, Bruno Roux +1 more |
2018-08-14 |
|
| 10039759 |
Quinolines as FGFR kinase modulators |
Valerio Berdini, Steven John Woodhead, Gordon Saxty |
2018-08-07 |
|
| 9856236 |
Substituted quinoxalines as FGFR kinase inhibitors |
Gordon Saxty, Christopher William Murray, Valerio Berdini, Gilbert Ebai Besong, Christopher Charles Frederick Hamlett +2 more |
2018-01-02 |
|
| 9850228 |
Pyrazolyl quinoxaline kinase inhibitors |
Gordon Saxty, Christopher William Murray, Valerio Berdini, Gilbert Ebai Besong, Christopher Charles Frederick Hamlett +20 more |
2017-12-26 |
|
| 9757364 |
Naphthyridine derivative compounds |
Michel Obringer, Julien Marin, Matthieu Jeanty |
2017-09-12 |
|
| 9737544 |
Compounds |
Isabelle Noëlle Constance Pilatte, Olivier Alexis Georges Querolle |
2017-08-22 |
|
| 9636341 |
Substituted indolyl alkyl amino derivatives as novel inhibitors of histone deacetylase |
Marc Gustaaf Celine Verdonck, Bruno Roux, Isabelle Noëlle Constance Pilatte, Peter Ten Holte, Janine Arts +1 more |
2017-05-02 |
$67,428,000 |
| 9598396 |
Tetrahydrophenanthridinones and tetrahydrocyclopentaquinolinones as PARP and tubulin polymerization inhibitors |
Laurence Anne Mevellec, Bruno Roux, Pierre-Henri Storck, Christophe Meyer, Jorge Eduardo Vialard |
2017-03-21 |
$98,944,000 |
