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Synthetic options towards the manufacture of (6R,10S)-10-{4-[5-chloro-2-(4-chloro-1H-1,2,3-triazol-1-yl)phenyl]-6-oxo-1(6H)-pyrimidinyl} - 1-(difluoromethyl)-6-methyl-1,4,7,8,9,10-hexahydro-11,15-(metheno)pyrazolo[4,3-b][1,7]diazacyclotetradecin-5(6H)-one |
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Pharmaceutical compositions comprising N-(3,5-dimethoxyphenyl)-N′-(1-methylethyl)-N-[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine |
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2023-06-27 |
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Bi-heteroaryl substitute 1,4-benzodiazepines and uses thereof for the treatment of cancer |
Patrick René Angibaud, Filip Albert C Cuyckens, Steven Anna Hostyn, Russell Mark Jones, Olivier Alexis Georges Querolle +1 more |
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Compounds |
Patrick René Angibaud, Helene France Solange Colombel, Filip Albert C Cuyckens, Steven Anna Hostyn, Russell Mark Jones +2 more |
2021-10-26 |
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Pharmaceutical compositions comprising N-(3,5-dimethoxyphenyl)-N'-1 methylethyl)-N-[3-(1-methyl-1H-pyrazol-4-yl)quinoxalin-6-yl]ethane-1,2-diamine |
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2021-01-26 |
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Quinoxaline derivatives useful as FGFR kinase modulators |
Wim Vermeulen, Steven Anna Hostyn, Filip Albert C Cuyckens, Russell Mark Jones |
2019-09-24 |
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Process for the preparation of histamine H3 receptor modulators |
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Substituted 2-[3-(1-methyl-piperidin-4-yl)-propylamino]-pyrimidine-5-carboxylic acids and amides and methods of making the same |
Matteo Conza, Oliver Flögel, Stefan Horns, Susanne Lochner, Guangrong Tang +2 more |
2018-10-16 |
| 9902714 |
Quinoxaline derivatives useful as FGFR kinase modulators |
Wim Vermeulen, Steven Anna Hostyn, Filip Albert C Cuyckens, Russell Mark Jones |
2018-02-27 |
| 9809547 |
Process for the preparation of histamine H3 receptor modulators |
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| 9796699 |
Substituted 2-[3-(1-methyl-piperidin-4-yl)-propylamino]-pyrimidine-5-carboxylic acids and amides and methods of making the same |
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Process for the preparation of histamine H3 receptor modulators |
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2016-12-13 |
| 9371311 |
Benzoimidazol-2-yl pyrimidine derivatives |
Neelakandha S. Mani, Christopher L. Mapes, Daniel J. Pippel |
2016-06-21 |
| 8921550 |
Process for the preparation of benzoimidazol-2-yl pyrimidine derivatives |
Neelakandha S. Mani, Christopher M. Mapes, Daniel J. Pippel |
2014-12-30 |
| 8835633 |
Process for the preparation of benzoimidazol-2-yl pyrimidine derivatives |
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Process for the preparation of histamine H3 receptor modulators |
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2014-06-10 |
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Process for the preparation of (−)-(4-chloro-phenyl)-(3-trifluoromethyl-phenoxy)-acetic acid 2-acetylamino-ethyl ester |
Hartmut Zinser |
2013-09-24 |
| 7939527 |
Thiazolopyridin-2-yloxy-phenyl and thiazolopyrazin-2-yloxy-phenyl amines as modulators of leukotriene A4 hydrolase |
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