Issued Patents All Time
Showing 1–25 of 52 patents
| Patent # | Title | Co-Inventors | Date |
|---|---|---|---|
| 11306081 | Phenylacetamides as inhibitors of rock | Michael J. Orwat | 2022-04-19 |
| 11299488 | Five membered-aminoheterocycle and 5,6-or 6,6-membered bicyclic aminoheterocyclic inhibitors of rock for the treatment of heart failure | Tarun Kumar Maishal | 2022-04-12 |
| 10829501 | Spiroheptane salicylamides and related compounds as inhibitors of ROCK | Leon M. Smith, II, Vladimir Ladziata, Indawati DeLucca, Michael J. Orwat, Andrew K. Dilger +5 more | 2020-11-10 |
| 10676477 | Factor XIa macrocycle inhibitors bearing a non-aromatic P2' group | Yeheng Zhu, Andrew K. Dilger, William R. Ewing, Michael J. Orwat | 2020-06-09 |
| 10611776 | Spiroheptane salicylamides and related compounds as inhibitors of rock | Leon M. Smith, II, Vladimir Ladziata, Indawati De Lucca, Michael J. Orwat, Andrew K. Dilger +5 more | 2020-04-07 |
| 10336730 | Substituted glycine derived FXIA inhibitors | James R. Corte, William R. Ewing, Leon M. Smith, II | 2019-07-02 |
| 10208021 | Substituted tetrahydroisoquinoline compounds as factor XIa inhibitors | Michael J. Orwat, Leon M. Smith, II, Shefali Srivastava | 2019-02-19 |
| 10000466 | Substituted 4,5,6,7-tetrahydropyrazolo[3,4-c]pyridines as factor XIa inhibitors | Michael J. Orwat, Leon M. Smith, II, James R. Corte, Shefali Srivastava | 2018-06-19 |
| 9944625 | Substituted tetrahydroisoquinoline compounds as factor XIa inhibitors | Michael J. Orwat, Leon M. Smith, II, Shefali Srivastava | 2018-04-17 |
| 9738655 | Tetrahydroisoquinolines containing substituted azoles as factor XIa inhibitors | Charles G. Clarke, Leon M. Smith, II, Michael J. Orwat, Yoon Jeon, James R. Corte | 2017-08-22 |
| 9725435 | Substituted 4,5,6,7-tetrahydropyrazolo[4,3-c]pyridines as factor XIa inhibitors | Michael J. Orwat, Leon M. Smith, II, James R. Corte, Shefali Srivastava | 2017-08-08 |
| 9447110 | Substituted tetrahydroisoquinoline compounds as factor XIa inhibitors | Michael J. Orwat, Leon M. Smith, II, Shefali Srivastava | 2016-09-20 |
| 9403774 | Guanidine and amine substituted tetrahydroisoquinoline compounds as factor xia inhibitors | Charles G. Clark, Michael J. Orwat, Leon M. Smith, II, William R. Ewing | 2016-08-02 |
| 9394276 | Substituted 1,2,3,4-tetrahydro-2,6-naphthyridines as factor XIa inhibitors | Michael J. Orwat, Leon M. Smith, II, James R. Corte, Shefali Srivastava | 2016-07-19 |
| 9315519 | Guanidine substituted tetrahydroisoquinoline compounds as factor XIa inhibitors | Charles G. Clark, Michael J. Orwat, Leon M. Smith, II, William R. Ewing | 2016-04-19 |
| 9192607 | Substituted tetrahydroisoquinoline compounds as factor XIa inhibitors | Michael J. Orwat, Leon M. Smith, II, Shefali Srivastava | 2015-11-24 |
| 9108951 | Substituted 5,6,7,8-tetrahydro-1,6-naphthyridines as factor XIa inhibitors | Michael J. Orwat, Leon M. Smith, II, James R. Corte, Shefali Srivastava | 2015-08-18 |
| 9079929 | Substituted tetrahydroisoquinoline compounds as factor XIa inhibitors | Michael J. Orwat, Leon M. Smith, II, Shefali Srivastava | 2015-07-14 |
| 9000172 | Substituted tetrahydroisoquinoline compounds as factor XIa inhibitors | Michael J. Orwat, Leon M. Smith, II, Shefali Srivastava | 2015-04-07 |
| 8410155 | Arylpropionamide, arylacrylamide, arylpropynamide, or arylmethylurea analogs as factor XIA inhibitors | — | 2013-04-02 |
| 8188120 | Lactam-containing compounds and derivatives thereof as factor Xa inhibitors | — | 2012-05-29 |
| 7960411 | Lactam-containing compounds and derivatives thereof as factor Xa inhibitors | — | 2011-06-14 |
| 7691846 | Lactam-containing compounds and derivatives thereof as factor Xa inhibitors | — | 2010-04-06 |
| 7338963 | Lactam-containing compounds and derivatives thereof as factor Xa inhibitors | — | 2008-03-04 |
| 7250415 | 1,1-Disubstitutedcycloalkyl-, glycinamidyl-, sulfonyl-amidino-, and tetrahydropyrimidinyl-containing diaminoalkyl, β-aminoacids, α-aminoacids and derivatives thereof as factor Xa inhibitors | Jennifer X. Qiao | 2007-07-31 |