| 12428413 |
Rho kinase inhibitors and compositions and methods of use thereof |
Michel C. Maillard, Celia Dominguez, Michael Barnes, Alan Findlay Haughan, Tammy Ladduwahetty +3 more |
2025-09-30 |
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| 12371435 |
Substituted imidazo[1,2-c]pyrimidines as PRC2 inhibitors |
Matthew Arnold Marx, Thomas P. Bobinski, Aaron Craig Burns, Nidhi Arora, James Gail Christensen +1 more |
2025-07-29 |
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| 12083108 |
Compounds for targeting mutant huntingtin protein and uses thereof |
Celia Dominguez, Jonathan Bard, Longbin Liu, Michael Prime, Samuel Coe |
2024-09-10 |
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| 11992535 |
Compounds and probes for imaging huntingtin protein |
Longbin Liu, Celia Dominguez, Peter David Johnson, Christopher John Brown, Sarah Hayes +3 more |
2024-05-28 |
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| 11932633 |
KRas G12C inhibitors |
Matthew Arnold Marx, James F. Blake, Mark Joseph Chicarelli, Jay Bradford Fell, John P. Fischer +5 more |
2024-03-19 |
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| 11918662 |
Heterocyclic compounds and imaging agents for imaging huntingtin protein |
Longbin Liu, Celia Dominguez, Peter David Johnson, Catherine Jane Greenaway, Kanika Khurana +2 more |
2024-03-05 |
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| 11912719 |
Substituted isoquinolines as rock kinase inhibitors |
Anthony Joseph Varano, Jr., Thomas P. Bobinski |
2024-02-27 |
|
| 11806346 |
HTT modulators for treating Huntington's disease |
Celia Dominguez, Elizabeth M. Doherty, Longbin Liu, Mark Stuart Chambers, Karine Fabienne Malagu +7 more |
2023-11-07 |
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| 11485738 |
Substituted imidazo[1,2-c]pyrimidines as PRC2 inhibitors |
Matthew Arnold Marx, Thomas P. Bobinski, Aaron Craig Burns, Nidhi Arora, James Gail Christensen +1 more |
2022-11-01 |
$69,121,000 |
| 11389438 |
Compounds for targeting mutant huntingtin protein and uses thereof |
Celia Dominguez, Jonathan Bard, Longbin Liu, Michael Prime, Samuel Coe |
2022-07-19 |
|
| 11267812 |
KRAS G12C inhibitors |
John P. Fischer, Jay Bradford Fell, James F. Blake, Ronald Jay Hinklin, Macedonio J. Mejia +10 more |
2022-03-08 |
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| 11248004 |
Substituted isoquinolines as rock kinase inhibitors |
Anthony Joseph Varano, Jr., Thomas P. Bobinski |
2022-02-15 |
|
| 11220509 |
Substituted imidazo[1,2-c]pyrimidines as PRC2 inhibitors |
Matthew Arnold Marx, Thomas P. Bobinski, Aaron Craig Burns, Nidhi Arora, James Gail Christensen +1 more |
2022-01-11 |
$74,630,000 |
| 11091495 |
Substituted imidazo[1,2-c]pyrimidines as PRC2 inhibitors |
Matthew Arnold Marx, Thomas P. Bobinski, Aaron Craig Burns, Nidhi Arora, James Gail Christensen +1 more |
2021-08-17 |
$71,942,000 |
| 10745381 |
Substituted isoquinolines and phthalazines as rock kinase inhibitors |
Anthony Joseph Varano, Jr. |
2020-08-18 |
|
| 10266542 |
EZH2 inhibitors |
Matthew Arnold Marx, Robert A. Galemmo, Jr., Thomas P. Bobinski |
2019-04-23 |
$32,759,000 |
| 9090593 |
Bicyclic compounds as Pim inhibitors |
Hui-Ling Wang, Kaustav Biswas, Victor J. Cee, Frank Chavez, Bradley J. Herberich +10 more |
2015-07-28 |
$306,601,000 |
| 8685983 |
Method of treating cancer with substituted amide derivatives |
Tae-Seong Kim, David Bauer, Steven Bellon, Alessadro Boezio, Shon Booker +17 more |
2014-04-01 |
$134,432,000 |
| 8088794 |
Substituted amide derivatives and methods of use |
Tae-Seong Kim, David Bauer, Steven Bellon, Alessandro Boezio, Shon Booker +17 more |
2012-01-03 |
$236,423,000 |
| 8084479 |
Thiazole compounds and methods of use |
Qingping Zeng, John Gordon Allen, Matthew P. Bourbeau, Celia Dominguez, Christopher H. Fotsch +14 more |
2011-12-27 |
$255,983,000 |
| 8017601 |
Bis-aryl kinase inhibitors and method |
Tae-Seong Kim, Jean-Christophe Harmange, Steven Bellon, Shon Booker, Noel D'Angelo +8 more |
2011-09-13 |
$73,740,000 |
| 7919504 |
Thiadiazole modulators of PKB |
Qingping Zeng, Chester Chenguang Yuan, Guomin Yao, Xianghong Wang, Seifu Tadesse +9 more |
2011-04-05 |
$78,787,000 |
| 7915287 |
Substituted heterocycles and methods of use |
Steven Bellon, Shon Booker, Noel D'Angelo, Julie Germain, Jean-Christophe Harmange +6 more |
2011-03-29 |
$115,359,000 |
| 7687522 |
Substituted pyridines and pyrimidines and their use in treatment of cancer |
Steven Bellon, Shon Booker, Noel D'Angelo, Ingrid M. Fellows, Jean-Christophe Harmange +3 more |
2010-03-30 |
$140,091,000 |
| 7652009 |
Substituted heterocycles and methods of use |
Tae-Seong Kim, Steven Bellon, Shon Booker, Noel D'Angelo, Celia Dominguez +7 more |
2010-01-26 |
|