| 12465603 |
Phthalazinone based modulators for the treatment of disease |
Nadia Ahmad, Christopher Rennie, William Rameshchandra Krishna Esmieu, Toby Jonathan Blench, Susan Mary Cramp +3 more |
2025-11-11 |
|
| 12281116 |
HTT modulators for treating Huntington's disease |
Longbin Liu, Celia Dominguez, Nikolay V. Plotnikov, Alan Findlay Haughan, Andrew J. Stott +6 more |
2025-04-22 |
|
| 12202816 |
Compounds as NADPH oxidase inhibitors |
Peter J. Machin, Alastair James Hodges, Andrew Sharpe, Grant Wishart, Benjamin Perry +2 more |
2025-01-21 |
|
| 12152038 |
Vasopressin receptor antagonists and products and methods related thereto |
Robert M. Jones, Mariangela Urbano, Gary E. L. Brandt, David Hardick, Chris Knight +2 more |
2024-11-26 |
$25,454,000 |
| 11806346 |
HTT modulators for treating Huntington's disease |
Celia Dominguez, Elizabeth M. Doherty, Longbin Liu, Matthew Lee, Karine Fabienne Malagu +7 more |
2023-11-07 |
|
| 11248001 |
PCSK9 inhibitors and methods of use thereof |
Michael H. Serrano-Wu, Erica Goldsmith, Jason Tierney, Karamjit Singh Jandu, David W. Clark +1 more |
2022-02-15 |
$120,757,000 |
| 10538530 |
Vasopressin receptor antagonists and products and methods related thereto |
Robert M. Jones, Mariangela Urbano, Gary E. L. Brandt, David Hardick, Chris Knight +2 more |
2020-01-21 |
|
| 10214509 |
Amino-substituted heterocyclic derivatives as sodium channel inhibitors |
James E. Duffy, Alastair Rae, James Daniel OSBORNE, Isabelle Anne LEMASSON, Michael Daniel Goldsmith +2 more |
2019-02-26 |
|
| 10130619 |
Amido thiadiazole derivatives as NADPH oxidase inhibitors |
Peter J. Machin, Andrew Sharpe, Christopher James Lock, Alastair James Hodges, VIVIENNE ALLEN +1 more |
2018-11-20 |
|
| 10016439 |
Fused imidazole compounds |
Tetsuji Saito, Masato Higashino, Soichi KAWAHARADA, Arwel Lewis, Alastair Rae +2 more |
2018-07-10 |
|
| 9212173 |
Pyrazole aminopyrimidine derivatives as LRRK2 modulators |
Charles Baker-Glenn, Daniel J. Burdick, Bryan Chan, Huifen Chen, Anthony A. Estrada +1 more |
2015-12-15 |
|
| 9145402 |
Aminopyrimidine derivatives as LRRK2 modulators |
Charles Baker-Glenn, Bryan Chan, Anthony A. Estrada, Daniel Shore, Zachary K. Sweeney +1 more |
2015-09-29 |
|
| 9006237 |
Fused pyrazine compounds useful for the treatment of degenerative and inflammatory diseases |
Martin James Inglis Andrews, Wolfgang Schmidt, Giovanni Alessandro Tricarico, Gregory Bar, Kim Louise Hirst +2 more |
2015-04-14 |
$52,905,000 |
| 8815882 |
Pyrazole aminopyrimidine derivatives as LRRK2 modulators |
Charles Baker-Glenn, Daniel J. Burdick, Bryan Chan, Huifen Chen, Anthony A. Estrada +1 more |
2014-08-26 |
|
| 8809331 |
Aminopyrimidine derivatives as LRRK2 modulators |
Charles Baker-Glenn, Daniel J. Burdick, Bryan Chan, Huifen Chen, Anthony A. Estrada +5 more |
2014-08-19 |
|
| 8802674 |
Aminopyrimidine derivatives as LRRK2 modulators |
Charles Baker-Glenn, Daniel J. Burdick, Bryan Chan, Huifen Chen, Anthony A. Estrada +5 more |
2014-08-12 |
|
| 8796296 |
Aminopyrimidine derivatives as LRRK2 modulators |
Charles Baker-Glenn, Bryan Chan, Anthony A. Estrada, Zachary K. Sweeney |
2014-08-05 |
|
| 8791130 |
Aminopyrimidine derivatives as LRRK2 modulators |
Charles Baker-Glenn, Bryan Chan, Anthony A. Estrada, Zachary K. Sweeney |
2014-07-29 |
|
| 8354420 |
Aminopyrimidine derivatives as LRRK2 inhibitors |
Charles Baker-Glenn, Daniel J. Burdick, Bryan Chan, Huifen Chen, Anthony A. Estrada +5 more |
2013-01-15 |
|
| 8178530 |
Imidazolopyrazine compounds useful for the treatment of degenerative and inflammatory diseases |
Martin James Inglis Andrews, Paul Edwards, Reginald Christophe Xavier Brys, Philip Huxley, Wolfgang Schmidt +6 more |
2012-05-15 |
$162,458,000 |
| 8173656 |
Imidazolopyrazine compounds useful for the treatment of degenerative and inflammatory diseases |
Martin James Inglis Andrews, Paul Edwards, Reginald Christophe Xavier Brys, Philip Huxley, Wolfgang Schmidt +6 more |
2012-05-08 |
$104,726,000 |
| 8148369 |
Fused pyrazine compounds useful for the treatment of degenerative and inflammatory diseases |
Martin James Inglis Andrews, Wolfgang Schmidt, Giovanni Alessandro Tricarico, Gregory Bar, Kim Louise Hirst +2 more |
2012-04-03 |
$38,531,000 |
| 8138193 |
Fused pyrazine compounds useful for the treatment of degenerative and inflammatory diseases |
Martin James Inglis Andrews, Wolfgang Schmidt, Gregory Bar |
2012-03-20 |
$58,490,000 |
| 8133895 |
Fused pyrazine compounds useful for the treatment of degenerative and inflammatory diseases |
Martin James Inglis Andrews, Wolfgang Schmidt, Gregory Bar |
2012-03-13 |
$84,129,000 |
| 8012983 |
Substituted triazolopyrazines useful for the treatment of degenerative and inflammatory diseases |
Martin James Inglis Andrews, Hervé Van De Poël, Gregory Bar |
2011-09-06 |
|
