Patent Leaderboard
USPTO Patent Rankings Data through Dec 31, 2025
MR

Mark Edward Ruppen — 61 Patents

Pfizer: 58 patents #6 of 5,153Top 1%
ACAmerican Cyanamid: 2 patents #617 of 1,554Top 40%
Bristol-Myers Squibb: 2 patents #1,827 of 3,969Top 50%
Cresco, PA: #1 of 15 inventorsTop 7%
Pennsylvania: #454 of 74,527 inventorsTop 1%
Overall (All Time): #37,626 of 4,157,543Top 1%
61 Patents All Time
Mark Edward Ruppen has been granted 61 US patents while listed as an inventor at Pfizer. The first was granted in 1991 and the most recent in July 2025. Mark Edward Ruppen ranks #37,626 of 4,157,543 US inventors in our database (top 0.91%). Patent records list Mark Edward Ruppen in Cresco, PA, US.

Issued Patents All Time

Showing 1–25 of 61 patents

Patent #TitleCo-InventorsDateApprox Value ⓘ
12364749 RSV F protein mutants Ye Che, Philip Dormitzer, Alexey Vyacheslavovich Gribenko, Luke David Handke, Avvari Krishna Prasad +9 more 2025-07-22
12128095 Escherichia coli compositions and methods thereof Robert G. K. Donald, Annaliesa Sybil Anderson, Laurent Oliver Chorro, Jianxin Gu, Jin-Hwan Kim +11 more 2024-10-29 $505,385,000
11952597 Compositions and methods relating to a mutant Clostridium difficile toxin Jason Arnold Lotvin, Annaliesa Sybil Anderson, Robert G. K. Donald, Michael James Flint, Narender Kumar Kalyan +4 more 2024-04-09 $435,588,000
11535652 Compositions relating to a mutant clostridium difficile toxin and methods thereof Kathrin Ute Jansen, Annaliesa Sybil Anderson, Robert G. K. Donald, Maninder K. Sidhu, Narender Kumar Kalyan +2 more 2022-12-27
11472850 Neisseria meningitidis composition and methods thereof Annaliesa Sybil Anderson, Susan Kay Hoiseth, Kathrin Ute Jansen, Justin Keith Moran 2022-10-18 $393,425,000
11260119 Escherichia coli compositions and methods thereof Robert G. K. Donald, Annaliesa Sybil Anderson, Laurent Oliver Chorro, Jianxin Gu, Jin-Hwan Kim +11 more 2022-03-01 $2,086,821,000
RE48863 Compositions relating to a mutant Clostridium difficile toxin and methods thereof Annaliesa Sybil Anderson, Maninder K. Sidhu, Robert G. K. Donald, Kathrin Ute Jansen, Narender Kumar Kalyan +2 more 2021-12-28
RE48862 Compositions relating to a mutant Clostridium difficile toxin and methods thereof Maninder K. Sidhu, Annaliesa Sybil Anderson, Robert G. K. Donald, Kathrin Ute Jansen, Narender Kumar Kalyan +2 more 2021-12-28
11208633 Compositions and methods relating to a mutant Clostridium difficile toxin Jason Arnold Lotvin, Annaliesa Sybil Anderson, Robert G. K. Donald, Michael James Flint, Narender Kumar Kalyan +4 more 2021-12-28 $2,337,647,000
11077180 Non-lipidated variants of Neisseria meningitidis ORF2086 antigens Annaliesa Sybil Anderson, Kathrin Ute Jansen, Justin Keith Moran, Susan Kay Hoiseth 2021-08-03
10982198 Compositions and methods relating to a mutant Clostridium difficile toxin Jason Arnold Lotvin, Annaliesa Sybil Anderson, Robert G. K. Donald, Michael James Flint, Narender Kumar Kalyan +4 more 2021-04-20 $674,734,000
10946086 Group B Streptococcus polysaccharide-protein conjugates, methods for producing conjugates, immunogenic compositions comprising conjugates, and uses thereof Annaliesa Sybil Anderson, Amardeep Singh Bhupender Bhalla, Robert G. K. Donald, Jianxin Gu, Kathrin Ute Jansen +8 more 2021-03-16 $365,212,000
10829521 Neisseria meningitidis composition and methods thereof Annaliesa Sybil Anderson, Susan Kay Hoiseth, Kathrin Ute Jansen, Justin Keith Moran 2020-11-10 $678,136,000
10821171 RSV F protein mutants Ye Che, Philip Dormitzer, Alexey Vyacheslavovich Gribenko, Luke David Handke, Avvari Krishna Prasad +9 more 2020-11-03 $385,583,000
10787652 Compositions and methods relating to a mutant clostridium difficile toxin Jason Arnold Lotvin, Annaliesa Sybil Anderson, Robert G. K. Donald, Michael James Flint, Narender Kumar Kalyan +4 more 2020-09-29 $414,122,000
10774117 Compositions relating to a mutant clostridium difficile toxin and methods thereof Kathrin Ute Jansen, Annaliesa Sybil Anderson, Robert G. K. Donald, Maninder K. Sidhu, Narender Kumar Kalyan +2 more 2020-09-15
10597428 Compositions relating to a mutant clostridium difficile toxin and methods thereof Kathrin Ute Jansen, Annaliesa Sybil Anderson, Robert G. K. Donald, Maninder K. Sidhu, Narender Kumar Kalyan +2 more 2020-03-24
10550159 Neisseria meningitidis composition and methods thereof Annaliesa Sybil Anderson, Susan Kay Hoiseth, Kathrin Ute Jansen, Justin Keith Moran 2020-02-04 $423,746,000
10512681 Non-lipidated variants of Neisseria meningitidis ORF2086 antigens Annaliesa Sybil Anderson, Kathrin Ute Jansen, Justin Keith Moran, Susan Kay Hoiseth 2019-12-24
10238732 RSV F protein mutants Ye Che, Philip Dormitzer, Alexey Vyacheslavovich Gribenko, Luke David Handke, Avvari Krishna Prasad +9 more 2019-03-26 $452,192,000
10226525 Group B Streptococcus polysaccharide-protein conjugates, methods for producing conjugates, immunogenic compositions comprising conjugates, and uses thereof Annaliesa Sybil Anderson, Amardeep Singh Bhupender Bhalla, Robert G. K. Donald, Jianxin Gu, Kathrin Ute Jansen +8 more 2019-03-12 $419,848,000
10196429 Neisseria meningitidis composition and methods thereof Annaliesa Sybil Anderson, Susan Kay Hoiseth, Kathrin Ute Jansen, Justin Keith Moran 2019-02-05 $450,590,000
9950058 RSV F protein mutants Ye Che, Philip Dormitzer, Alexey Vyacheslavovich Gribenko, Luke David Handke, Avvari Krishna Prasad +9 more 2018-04-24 $328,572,000
9802987 Immunogenic fusion polypeptides Deborah Ann Dilts, Annaliesa Sybil Anderson, Kathrin Ute Jansen, Justin Keith Moran, Eugene Joseph Vidunas 2017-10-31 $245,690,000
9757443 Non-lipidated variants of Neisseria meningitidis ORF2086 antigens Annaliesa Sybil Anderson, Kathrin Ute Jansen, Justin Keith Moran, Susan Kay Hoiseth 2017-09-12