| 12252490 |
Inhibiting deubiquitinase USP25 and USP28 |
David Joseph Guerin, Justin Andrew Caravella, Hongbin Li, Steven Mischke, Shawn Schiller +1 more |
2025-03-18 |
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| 12128035 |
Activating pyruvate kinase R |
Anna Ericsson, Neal Green, Gary Gustafson, David R. Lancia, Jr., Gary Marshall +7 more |
2024-10-29 |
$114,666,000 |
| 12122778 |
Activating pyruvate kinase R |
Xiaozhang Zheng, Anna Ericsson, Neal Green, Gary Gustafson, David R. Lancia, Jr. +3 more |
2024-10-22 |
$83,936,000 |
| 12071440 |
Pyrrolopyrrole compositions as pyruvate kinase (PKR) activators |
Anna Ericsson, Neal Green, Gary Gustafson, Bingsong Han, David R. Lancia, Jr. +5 more |
2024-08-27 |
$103,900,000 |
| 12053458 |
Treating sickle cell disease with a pyruvate kinase R activating compound |
Anna Ericsson, Neal Green, Gary Gustafson, David R. Lancia, Jr., Bingsong Han +5 more |
2024-08-06 |
$208,108,000 |
| 11980611 |
Treating sickle cell disease with a pyruvate kinase R activating compound |
Anna Ericsson, Neal Green, Gary Gustafson, Bingsong Han, David R. Lancia, Jr. +5 more |
2024-05-14 |
$216,614,000 |
| 11844787 |
Activating pyruvate kinase R |
Anna Ericsson, Neal Green, Gary Gustafson, David R. Lancia, Jr., Gary Marshall +2 more |
2023-12-19 |
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| 11814386 |
Fused pyrrolines which act as ubiquitin-specific protease 30 (USP30) inhibitors |
Alex J. Buckmelter, Justin Andrew Caravella, Hongbin Li, Matthew W. Martin, Steven Mischke +1 more |
2023-11-14 |
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| 11649242 |
Pyrrolopyrrole compositions as pyruvate kinase (PKR) activators |
Anna Ericsson, Neal Green, Gary Gustafson, Bingsong Han, David R. Lancia, Jr. +5 more |
2023-05-16 |
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| 11535618 |
Fused pyrrolines which act as ubiquitin-specific protease 30 (USP30) inhibitors |
Alex J. Buckmelter, Justin Andrew Caravella, Hongbin Li, Matthew W. Martin, Steven Mischke +1 more |
2022-12-27 |
|
| 11325917 |
Thienopyrazine carboxamides as ubiquitin-specific protease inhibitors |
David Joseph Guerin, Kenneth W. Bair, Justin Andrew Caravella, Stephanos Ioannidis, David R. Lancia, Jr. +6 more |
2022-05-10 |
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| 11247987 |
Inhibiting ubiquitin specific peptidase 30 |
Justin Andrew Caravella, Bingsong Han, Cuixian Liu, Stephanos Ioannidis, Alexandre Joseph Buckmelter +3 more |
2022-02-15 |
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| 11071725 |
Activating pyruvate kinase R |
Anna Ericsson, Neal Green, Gary Gustafson, David R. Lancia, Jr., Gary Marshall +2 more |
2021-07-27 |
|
| 11014927 |
Pyrrolopyrrole compositions as pyruvate kinase (PKR) activators |
Anna Ericsson, Neal Green, Gary Gustafson, Bingsong Han, David R. Lancia, Jr. +5 more |
2021-05-25 |
|
| 11001588 |
Activating pyruvate kinase R and mutants thereof |
David R. Lancia, Jr., Gary Gustafson, Neal Green, Lorna Helen Mitchell, Anna Ericsson |
2021-05-11 |
|
| 10913753 |
Thienopyridine carboxamides as ubiquitin-specific protease inhibitors |
David Joseph Guerin, Kenneth W. Bair, Justin Andrew Caravella, Stephanos Ioannidis, David R. Lancia, Jr. +6 more |
2021-02-09 |
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| 10889592 |
Thienopyrazine carboxamides as ubiquitin-specific protease inhibitors |
David Joseph Guerin, Kenneth W. Bair, Justin Andrew Caravella, Stephanos Ioannidis, David R. Lancia, Jr. +6 more |
2021-01-12 |
|
| 10765673 |
Methods and compositions useful for treating diseases involving Bcl-2 family proteins with quinoline derivatives |
Michael H. Cardone |
2020-09-08 |
|
| 10675274 |
Activating pyruvate kinase R |
Anna Ericsson, Neal Green, Gary Gustafson, David R. Lancia, Jr., Gary Marshall +2 more |
2020-06-09 |
|
| 10413549 |
Methods and compositions useful for treating diseases involving Bcl-2 family proteins with isoquinoline and quinoline derivatives |
Michael H. Cardone |
2019-09-17 |
|
| 10022381 |
Triazine compounds as PI3 kinase and mTOR inhibitors |
Aranapakam Mudumbai Venkatesan, Zecheng Chen, Christoph Martin Dehnhardt, Osvaldo Dos Santos, Efren Guillermo Delos Santos +8 more |
2018-07-17 |
$209,955,000 |
| 9345700 |
Compositions and methods useful for treating diseases |
Michael H. Cardone, Andrew Kolodziej |
2016-05-24 |
|
| 9174963 |
Triazine compounds as PI3 kinase and MTOR inhibitors |
Aranapakam Mudumbai Venkatesan, Zecheng Chen, Christoph Martin Dehnhardt, Osvaldo Dos Santos, Efren Guillermo Delos Santos +8 more |
2015-11-03 |
$641,346,000 |
| 9051305 |
Compositions and methods useful for treating diseases |
Michael H. Cardone, Andrew Kolodziej |
2015-06-09 |
|
| 8859542 |
Triazine compounds as PI3 kinase and mTOR inhibitors |
Aranapakam Mudumbai Venkatesan, Zecheng Chen, Christoph Martin Dehnhardt, Osvaldo Dos Santos, Efren Guillermo Delos Santos +8 more |
2014-10-14 |
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