| 12378242 |
Inhibiting CREB binding protein (CBP) |
Shawn Schiller, Torsten Herbertz, Hongbin Li, Bradford Graves, Steven Mischke +2 more |
2025-08-05 |
|
| 12351577 |
Inhibiting cyclic AMP-responsive element-binding protein (CREB) |
Shawn Schiller, Torsten Herbertz, Hongbin Li, Bradford Graves, Steven Mischke +2 more |
2025-07-08 |
|
| 12275715 |
Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors |
Jian Lin, Ann-Marie Campbell, Gary Gustafson, Zhongguo Wang, R. Bruce Diebold +4 more |
2025-04-15 |
|
| 12128035 |
Activating pyruvate kinase R |
Neal Green, Gary Gustafson, David R. Lancia, Jr., Gary Marshall, Lorna Helen Mitchell +7 more |
2024-10-29 |
$114,666,000 |
| 12122778 |
Activating pyruvate kinase R |
Xiaozhang Zheng, Neal Green, Gary Gustafson, David R. Lancia, Jr., Jian Lin +3 more |
2024-10-22 |
$83,936,000 |
| 12071440 |
Pyrrolopyrrole compositions as pyruvate kinase (PKR) activators |
Neal Green, Gary Gustafson, Bingsong Han, David R. Lancia, Jr., Lorna Helen Mitchell +5 more |
2024-08-27 |
$103,900,000 |
| 12053458 |
Treating sickle cell disease with a pyruvate kinase R activating compound |
Neal Green, Gary Gustafson, David R. Lancia, Jr., Bingsong Han, Lorna Helen Mitchell +5 more |
2024-08-06 |
$208,108,000 |
| 12018030 |
Pyrrolo and pyrazolopyrimidines as ubiquitin-specific protease 7 inhibitors |
Stephanos Ioannidis, Adam Charles Talbot, Bruce Follows, Alexandre Joseph Buckmelter, Minghua Wang +6 more |
2024-06-25 |
|
| 11980611 |
Treating sickle cell disease with a pyruvate kinase R activating compound |
Neal Green, Gary Gustafson, Bingsong Han, David R. Lancia, Jr., Lorna Helen Mitchell +5 more |
2024-05-14 |
$216,614,000 |
| 11844787 |
Activating pyruvate kinase R |
Neal Green, Gary Gustafson, David R. Lancia, Jr., Gary Marshall, Lorna Helen Mitchell +2 more |
2023-12-19 |
|
| 11801243 |
Bromodomain inhibitors for androgen receptor-driven cancers |
Sylvie GUICHARD, Maureen Caligiuri, Qunli Xu, Hesham Mohamed |
2023-10-31 |
|
| 11787803 |
Tetrahydro-imidazo quinoline compositions as CBP/P300 inhibitors |
Shawn Schiller, Torsten Herbertz, Hongbin Li, Bradford Graves, Steven Mischke +2 more |
2023-10-17 |
|
| 11649242 |
Pyrrolopyrrole compositions as pyruvate kinase (PKR) activators |
Neal Green, Gary Gustafson, Bingsong Han, David R. Lancia, Jr., Lorna Helen Mitchell +5 more |
2023-05-16 |
|
| 11498913 |
Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors |
Jian Lin, Ann-Marie Campbell, Gary Gustafson, Zhongguo Wang, R. Bruce Diebold +4 more |
2022-11-15 |
|
| 11292791 |
Tetrahydro-imidazo quinoline compositions as CBP/P300 inhibitors |
Shawn Schiller, Torsten Herbertz, Hongbin Li, Bradford Graves, Steven Mischke +2 more |
2022-04-05 |
|
| 11254674 |
Inhibiting CREB binding protein (CBP) |
Shawn Schiller, Torsten Herbertz, Hongbin Li, Bradford Graves, Steven Mischke +2 more |
2022-02-22 |
|
| 11071725 |
Activating pyruvate kinase R |
Neal Green, Gary Gustafson, David R. Lancia, Jr., Gary Marshall, Lorna Helen Mitchell +2 more |
2021-07-27 |
|
| 11014927 |
Pyrrolopyrrole compositions as pyruvate kinase (PKR) activators |
Neal Green, Gary Gustafson, Bingsong Han, David R. Lancia, Jr., Lorna Helen Mitchell +5 more |
2021-05-25 |
|
| 11001588 |
Activating pyruvate kinase R and mutants thereof |
David R. Lancia, Jr., Gary Gustafson, Neal Green, Lorna Helen Mitchell, David Richard |
2021-05-11 |
|
| 10934299 |
Pyrrolo and pyrazolopyrimidines as ubiquitin-specific protease 7 inhibitors |
Stephanos Ioannidis, Adam Charles Talbot, Bruce Follows, Alexandre Joseph Buckmelter, Minghua Wang +6 more |
2021-03-02 |
|
| 10889567 |
Pyridin-2(1H)-one quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors |
Jian Lin, Ann-Marie Campbell, Gary Gustafson, Zhongguo Wang, R. Bruce Diebold +4 more |
2021-01-12 |
|
| 10870648 |
Inhibiting CREB binding protein (CBP) |
Shawn Schiller, Torsten Herbertz, Hongbin Li, Bradford Graves, Steven Mischke +2 more |
2020-12-22 |
|
| 10807976 |
Quinolinone five-membered heterocyclic compounds as mutant-isocitrate dehydrogenase inhibitors |
Jian Lin, Ann-Marie Campbell, Gary Gustafson, Zhongguo Wang, R. Bruce Diebold +4 more |
2020-10-20 |
|
| 10675274 |
Activating pyruvate kinase R |
Neal Green, Gary Gustafson, David R. Lancia, Jr., Gary Marshall, Lorna Helen Mitchell +2 more |
2020-06-09 |
|
| 10577329 |
Fused-bicyclic aryl quinolinone derivatives as mutant-isocitrate dehydrogenase inhibitors |
Jian Lin, Ann-Marie Campbell, Gary Gustafson, Zhongguo Wang, R. Bruce Diebold +4 more |
2020-03-03 |
|
