| 6569461 |
Dihydroxy open-acid and salts of HMG-CoA reductase inhibitors |
Richard D. Tillyer, Edward J. J. Grabowski, Feng Xu, Jose Vega, Mandana Asgharnejad |
2003-05-27 |
$103,128,000 |
| 6395894 |
Process for the synthesis of carbapenem intermidiates, and compounds produced |
Philip Pye, Kai Rossen, Ralph P. Volante |
2002-05-28 |
|
| 6242596 |
Preparation of betamethyl carbapenem intermediates |
Woo-Baeg Choi, Guy R. Humphrey, Ichiro Shinkai, Andrew S. Thompson, Ralph P. Volante |
2001-06-05 |
$193,637,000 |
| 6156895 |
Process for preparing 4-tert-butyloxycarbonyl-(S)-piperazine-2-tert-butylcarboxamide |
Kai Rossen, Philip Pye, Ralph P. Volante |
2000-12-05 |
$236,503,000 |
| 6143885 |
Preparation of beta-methyl carbapenem intermediates |
Woo-Baeg Choi, Jaemoon Lee, Joseph E. Lynch, Ralph P. Volante |
2000-11-07 |
$242,943,000 |
| 6071916 |
HIV protease inhibitor |
David Askin, Robert Purick, R. Scott Hoerrner, Richard J. Varsolona, Ralph P. Volante |
2000-06-06 |
$181,911,000 |
| 6025500 |
Stereoselective process for enalapril |
Mark A. Huffman, Carl Leblond, Yongkui Sun |
2000-02-15 |
$200,815,000 |
| 5998612 |
Antibiotic synthesis |
Edward J. J. Grabowski |
1999-12-07 |
|
| 5977364 |
Process for preparing 4-tert-butyloxycarbonyl-(S)-piperazine-2-tert-butylcarboxamide |
Kai Rossen, Philip Pye, Ralph P. Volante |
1999-11-02 |
$99,873,000 |
| 5952528 |
Process for enhancing the optical purity |
Cheng-Yi Chen, Edward J. J. Grabowski, Lushi Tan, Richard D. Tillyer |
1999-09-14 |
$82,986,000 |
| 5861512 |
Process for making HIV protese inhibitors |
David Askin, Kai Rossen, Richard J. Varsolona, Ralph P. Volante, Kenneth M. Wells |
1999-01-19 |
$138,149,000 |
| 5858737 |
Conversion of indene to (1S)-amino-(2R)-indanol free of any stereoisomer, by combination of dioxygenase bioconversion and chemical steps |
Barry C. Buckland, Neal C. Connors, Michel Chartrain, Francis P. Gailliot, Randolph L. Greasham +7 more |
1999-01-12 |
$99,858,000 |
| 5808082 |
Method of preparing phosphodiesterase IV inhibitors |
Woo-Baeg Choi, Hywyn R.O. Churchill, Joseph E. Lynch, Ralph P. Volante |
1998-09-15 |
$102,867,000 |
| 5728840 |
Process for making an epoxide |
David Askin, Kan K. Eng, Peter E. Maligres, Kai Rossen, Ralph P. Volante +2 more |
1998-03-17 |
$111,836,000 |
| 5723615 |
Process for preparing 4-tert-butyloxycarbonyl-(S)-piperazine-2-tert-butylcarboxamide |
Kai Rossen, Steven A. Weissman, Jess Sager, David Askin, Ralph P. Volante |
1998-03-03 |
$124,388,000 |
| 5693803 |
Process for making HIV protease inhibitors |
David Askin, Kai Rossen, Richard J. Varsolona, Ralph P. Volante, Kenneth M. Wells |
1997-12-02 |
$56,997,000 |
| 5663341 |
Process for making HIV protease inhibitors |
Kai Rossen, David Askin, Richard J. Varsolona, Ralph P. Volante |
1997-09-02 |
$56,127,000 |
| 5654424 |
Preparation of beta-methyl carbapenem intermediates |
Woo-Baeg Choi, Guy R. Humphrey, Ichiro Shinkai, Andrew S. Thompson, Ralph P. Volante |
1997-08-05 |
$606,226,000 |
| 5637711 |
Process for making HIV protease inhibitors |
David Askin, Kai Rossen, Richard J. Varsolona, Ralph P. Volante, Kenneth M. Wells |
1997-06-10 |
$116,710,000 |
| 5618937 |
Process to make HIV protease inhibitor from (2S)-4-picolyl-2-piperazine-t-butylcarboxamide |
David Askin, Kan K. Eng, Ralph P. Volante |
1997-04-08 |
$51,720,000 |
| 5618939 |
Process for making HIV protease inhibitors |
David Askin, Kai Rossen, Richard J. Varsolona, Ralph P. Volante, Kenneth M. Wells |
1997-04-08 |
$51,720,000 |
| 5612484 |
Process for making HIV protease inhibitors |
David Askin, Jess Sager, Kai Rossen, Ralph P. Volante |
1997-03-18 |
$78,728,000 |
| 5489685 |
Method of synthesizing furo[2,3-b]pyridine carboxylic acid esters |
Ioannis Nicolaos Houpis, Audrey Molina, Joseph E. Lynch, Hywyn R.O. Churchill, Ralph P. Volante +1 more |
1996-02-06 |
$137,062,000 |
| 5070022 |
Enzymic process for preparing leukotriene antagonists |
David L. Hughes, Joseph S. Amato, James Bergan, Edward J. J. Grabowski |
1991-12-03 |
$113,521,000 |
| 4946997 |
Racemization of a carboxylic acid |
Robert D. Larsen |
1990-08-07 |
$26,108,000 |
