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Aryl dihydro-2H benzo[b][1,4]oxazine sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease |
Clarke B. Taylor, Chad A. VanHuis |
2021-07-13 |
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Tetrahydronaphthyridine, benzoxazine, aza-benzoxazine and related bicyclic compounds for inhibition of RORgamma activity and the treatment of disease |
Chad A. VanHuis, William D. Thomas, John MacLean, Brian M. Andresen, Kenneth J. Barr +9 more |
2020-08-18 |
$154,425,000 |
| 10611740 |
Aryl dihydro-2H-benzo[b][1,4]oxazine sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease |
Clarke B. Taylor, Chad A. VanHuis |
2020-04-07 |
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Indazolyl-1,2,4-thiadiazolamines and related compounds for inhibition of Rho-associated protein kinase and the treatment of disease |
Fernando Padilla, Donald J. Skalitzky, Peter L. Toogood, Chad A. VanHuis |
2020-02-11 |
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Adoptive cellular therapy using an agonist of retinoic acid receptor-related orphan receptor gamma and related therapeutic methods |
Gary D. Glick, Peter L. Toogood, Xiao Hu, Laura L. Celeste, Xikui Liu +2 more |
2020-01-14 |
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Tetrahydroquinoline sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease |
Clarke B. Taylor, Chad A. VanHuis |
2019-10-15 |
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Dihydro-2H-benzo[b][1,4]oxazine sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease |
Clarke B. Taylor, Chad A. VanHuis |
2019-09-24 |
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N-substituted pyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof |
Donald J. Skalitzky, Clarke B. Taylor |
2019-08-27 |
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Tetrahydronaphthyridine and related bicyclic compounds for inhibition of RORgamma activity and the treatment of disease |
Kenneth J. Barr, Blair T. Lapointe, Vladimir Simov, Karin Ann Stein, William D. Thomas +3 more |
2019-08-13 |
$124,537,000 |
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Tetrahydroquinoline sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease |
Clarke B. Taylor, Chad A. VanHuis |
2019-07-30 |
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Tetrahydronaphthyridine, benzoxazine, aza-benzoxazine and related bicyclic compounds for inhibition of RORgamma activity and the treatment of disease |
Chad A. VanHuis, William D. Thomas, John MacLean, Brian M. Andresen, Kenneth J. Barr +9 more |
2019-03-05 |
$69,271,000 |
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Tetrahydro[1,8]naphthyridine sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease |
Peter L. Toogood, Xiao Hu |
2019-02-19 |
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Benzenesulfonamido and related compounds for use as agonists of RORγ and the treatment of disease |
Donald J. Skalitzky, Clarke B. Taylor, Chad A. Van Huis |
2019-01-29 |
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Indazolyl thiadiazolamines and related compounds for inhibition of Rho-associated protein kinase and the treatment of disease |
Fernando Padilla, Peter L. Toogood, Shoujun Chen |
2018-10-30 |
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| 10017482 |
Mitotic kinesin inhibitors and methods of use thereof |
Jeremy Hans, Eli M. Wallace, Qian Zhao, Joseph P. Lyssikatos, Ellen Laird +2 more |
2018-07-10 |
$44,836,000 |
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N-substituted pyrazolyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof |
Donald J. Skalitzky, Clarke B. Taylor |
2018-03-13 |
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Tetrahydroquinoline sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease |
Clarke B. Taylor, Chad A. VanHuis |
2018-02-20 |
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Tetrahydronaphthyridine, benzoxazine, aza-benzoxazine and related bicyclic compounds for inhibition of RORgamma activity and the treatment of disease |
Chad A. VanHuis, William D. Thomas, John MacLean, Brian M. Andresen, Kenneth J. Barr +9 more |
2017-11-07 |
$37,151,000 |
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Tetrahydro[1,8]naphthyridine sulfonamide and related compounds for use as agonists of RORy and the treatment of disease |
Peter L. Toogood, Xiao Hu |
2017-10-31 |
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Carbamate benzoxazine propionic acids and acid derivatives for modulation of RORgamma activity and the treatment of disease |
Chad A. VanHuis, John MacLean, Brian M. Andresen, Kenneth J. Barr, Corey E. Bienstock +6 more |
2017-10-10 |
$124,275,000 |
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2-Acylamidomethyl and sulfonylamidomethyl benzoxazine carbamates for inhibition of RORgamma activity and the treatment of disease |
Chad A. VanHuis, John MacLean, Brian M. Andresen, Kenneth J. Barr, Corey E. Bienstock +9 more |
2017-05-30 |
$63,958,000 |
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Tetrahydronaphthyridine and related bicyclic compounds for inhibition of RORγ activity and the treatment of disease |
Kenneth J. Barr, Blair T. Lapointe, Vladimir Simov, Karin Ann Stein, William D. Thomas +3 more |
2017-05-23 |
$97,197,000 |
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N-sulfonylated tetrahydroquinolines and related bicyclic compounds for inhibition of RORγ activity and the treatment of disease |
Gary D. Glick, Peter L. Toogood, Arthur Glenn Romero, Chad A. Van Huis, Carl Kaub +5 more |
2016-12-06 |
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Mitotic kinesin inhibitors and methods of use thereof |
Jeremy Hans, Eli M. Wallace, Qian Zhao, Joseph P. Lyssikatos, Ellen Laird +2 more |
2016-11-22 |
$32,720,000 |
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Tetrahydro[1,8]naphthyridine sulfonamide and related compounds for use as agonists of RORγ and the treatment of disease |
Peter L. Toogood, Xiao Hu |
2016-07-19 |
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