| 8778984 |
Aldosterone synthase inhibitor |
Michael Gregory Bell, Paul J. Hoogestraat, Quanrong Shen, Ana Maria Escribano |
2014-07-15 |
$65,923,000 |
| 8153807 |
Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
Julie Kay Bush, Marvin M. Hansen, Renhua Li, Nancy June Snyder, Owen Brendan Wallace +1 more |
2012-04-10 |
$63,797,000 |
| 7994176 |
Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
Renhua Li, Owen Brendan Wallace, Leonard Larry Winneroski, Jr., Yanping Xu |
2011-08-09 |
$42,609,000 |
| 7981918 |
Cyclohexylpyrazole-lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
Thomas D. Aicher, Peter B. Anzeveno, Renhua Li, Alexei Pavlovych Krasutsky, Ashraf Saeed +5 more |
2011-07-19 |
$50,826,000 |
| 7968585 |
Inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
Owen Brendan Wallace, Yanping Xu, Nancy June Snyder, Leonard Larry Winneroski, Jr. |
2011-06-28 |
$46,527,000 |
| 7820659 |
Cyclohexylimidiazole lactam derivatives as inhibitors of 11-β-hydroxysteroid dehydrogenase 1 |
Ashraf Saeed, Owen Brendan Wallace, Yanping Xu, Rebecca Lynn Rezac Guenther, Nancy June Snyder |
2010-10-26 |
$58,022,000 |
| 7713979 |
Cycloalkyl lactam derivatives as inhibitors of 11-beta-hydroxysteroid dehydrogenase 1 |
Thomas D. Aicher, Mark Joseph Chicarelli, Ronald Jay Hinklin, Hongqi Tian, Owen Brendan Wallace +5 more |
2010-05-11 |
$176,974,000 |
| 7153847 |
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
Jing Wu, Jay Tung, Jeffrey S. Nissen, R. Jeffrey Neitz, James Audia |
2006-12-26 |
$89,417,000 |
| 6958330 |
Polycyclic α-amino-ε-caprolactams and related compounds |
James E. Audia, Jeffrey A. Nissen, Stacey L. McDaniel, Warren J. Porter |
2005-10-25 |
$273,474,000 |
| 6951854 |
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
Jing Wu, Jay Tung, Eugene D. Thorsett, Michael A. Pleiss, Jeffrey S. Nissen +15 more |
2005-10-04 |
$166,498,000 |
| 6906056 |
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds |
Richard Thompson, Stephen Wilkie, Douglas Richard Stack, Eldon Vanmeter, Qing Shi +9 more |
2005-06-14 |
$111,693,000 |
| 6888022 |
Methods and compounds for inhibiting β-amyloid peptide release and/or its synthesis |
James E. Audia, Thomas C. Britton, James J. Droste, Beverly Folmer, George W. Huffman +10 more |
2005-05-03 |
$355,087,000 |
| 6861558 |
Methods and compounds for inhibiting β-amyloid peptide release and/or its synthesis |
James E. Audia, Thomas C. Britton, James J. Droste, Beverly Folmer, George W. Huffman +10 more |
2005-03-01 |
$288,702,000 |
| 6767918 |
N-(aryl/heteroarylacetyl) amino acid esters, pharmaceutical compositions comprising same, and methods for inhibiting &bgr;-amyloid peptide release and/or its synthesis by use of such compounds |
Jing Wu, Eugene D. Thorsett, Jeffrey S. Nissen, Lee H. Latimer, Varghese John +2 more |
2004-07-27 |
$188,934,000 |
| 6683075 |
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting &bgr;-amyloid peptide release and/or its synthesis by use |
Jing Wu, Jay Tung, Eugene D. Thorsett, Michael A. Pleiss, Jeffrey S. Nissen +15 more |
2004-01-27 |
$227,818,000 |
| 6667305 |
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting &bgr;-amyloid peptide release and/or its synthesis by use of such compounds |
Jing Wu, Jay Tung, Eugene D. Thorsett, Michael A. Pleiss, Jeffrey S. Nissen +15 more |
2003-12-23 |
$217,765,000 |
| 6653303 |
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting &bgr;-amyloid peptide release and/or its synthesis by use of such compounds |
Jing Wu, Jay Tung, Eugene D. Thorsett, Michael A. Pleiss, Jeffrey S. Nissen +15 more |
2003-11-25 |
$111,856,000 |
| 6642261 |
N-(aryl/heteroarylacety) amino acid esters, pharmaceutical compositions comprising same, and methods for inhibiting &bgr;-amyloid peptide release and/or its synthesis by use of such compounds |
Jing Wu, Eugene D. Thorsett, Jeffrey S. Nissen, Lee H. Latimer, Varghese John +2 more |
2003-11-04 |
$448,860,000 |
| 6635632 |
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting &bgr;-amyloid peptide release and/or its synthesis by use of such compounds |
Jing Wu, Jay Tung, Eugene D. Thorsett, Michael A. Pleiss, Jeffrey S. Nissen +15 more |
2003-10-21 |
$164,015,000 |
| 6632811 |
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting &bgr;-amyloid peptide release and/or its synthesis by use of such compounds |
Jing Wu, Jay Tung, Eugene D. Thorsett, Michael A. Pleiss, Jeffrey S. Nissen +15 more |
2003-10-14 |
$430,244,000 |
| 6579867 |
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting &bgr;-amyloid peptide release and/or its synthesis by use of such compounds |
Jing Wu, Jay Tung, Eugene D. Thorsett, Michael A. Pleiss, Jeffrey S. Nissen +13 more |
2003-06-17 |
$179,653,000 |
| 6569851 |
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting &bgr;-amyloid peptide release and/or its synthesis by use of such compounds |
Richard Thompson, Stephen Wilkie, Douglas Richard Stack, Eldon Vanmeter, Qing Shi +9 more |
2003-05-27 |
$145,984,000 |
| 6559141 |
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting &bgr;-amyloid peptide release and/or its synthesis by use of such compounds |
Jing Wu, Jay Tung, Eugene D. Thorsett, Michael A. Pleiss, Jeffrey S. Nissen +15 more |
2003-05-06 |
$249,005,000 |
| 6544978 |
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting &bgr;-amyloid peptide release and/or its synthesis by use of such compounds |
Jing Wu, Jay Tung, Eugene D. Thorsett, Michael A. Pleiss, Jeffrey S. Nissen +15 more |
2003-04-08 |
$238,604,000 |
| 6541466 |
Cycloalkyl, lactam, lactone and related compounds, pharmaceutical compositions comprising same, and methods for inhibiting &bgr;-amyloid peptide release and/or its synthesis by use of such compounds |
Jing Wu, Jay Tung, Eugene D. Thorsett, Michael A. Pleiss, Jeffrey S. Nissen +15 more |
2003-04-01 |
$118,606,000 |
