Patent Leaderboard
USPTO Patent Rankings Data through Dec 31, 2025
JG

John M. Gruber — 40 Patents

COCodexis: 31 patents #21 of 250Top 9%
CACatalytic: 3 patents #20 of 77Top 30%
SASandoz Ag: 3 patents #174 of 1,103Top 20%
Pfizer: 2 patents #2,085 of 5,153Top 45%
Mountain View, CA: #384 of 11,022 inventorsTop 4%
California: #11,486 of 386,348 inventorsTop 3%
Overall (All Time): #78,057 of 4,157,543Top 2%
40 Patents All Time
John M. Gruber has been granted 40 US patents while listed as an inventor at Codexis. The first was granted in 1989 and the most recent in September 2025. John M. Gruber ranks #78,057 of 4,157,543 US inventors in our database (top 1.9%). Patent records list John M. Gruber in Mountain View, CA, US.

Issued Patents All Time

Showing 1–25 of 40 patents

Patent #TitleCo-InventorsDateApprox Value ⓘ
12415990 Ketoreductase polypeptides for the reduction of acetophenones Jack Liang, Stephane J. Jenne, Emily Mundorff, Charlene Ching, Anke Krebber +1 more 2025-09-16
12365927 Engineered ketoreductase polypeptides Christopher Savile, Emily Mundorff, Gjalt W. Huisman, Steven J. Collier 2025-07-22
11512332 Engineered ketoreductase polypeptides Christopher Savile, Emily Mundorff, Gjalt W. Huisman, Steven J. Collier 2022-11-29 $6,836,000
11479756 Ketoreductase polypeptides for the reduction of acetophenones Jack Liang, Stephane J. Jenne, Emily Mundorff, Charlene Ching, Anke Krebber +1 more 2022-10-25 $6,773,000
10927351 Ketoreductase polypeptides for the reduction of acetophenones Jack Liang, Stephane J. Jenne, Emily Mundorff, Charlene Ching, Anke Krebber +1 more 2021-02-23 $19,692,000
10752926 Engineered ketoreductase polypeptides Christopher Savile, Emily Mundorff, Gjalt W. Huisman, Steven J. Collier 2020-08-25 $8,976,000
10227572 Ketoreductase polypeptides for the reduction of acetophenones Jack Liang, Stephane J. Jenne, Emily Mundorff, Charlene Ching, Anke Krebber +1 more 2019-03-12 $12,843,000
10100288 Ketoreductase polypeptides for the reduction of acetophenones Jack Liang, Stephane J. Jenne, Emily Mundorff, Charlene Ching, Anke Krebber +1 more 2018-10-16 $3,342,000
10006069 Engineered ketoreductase polypeptides Christopher Savile, Emily Mundorff, Gjalt W. Huisman, Steven J. Collier 2018-06-26 $9,093,000
9951318 Ketoreductase polypeptides for the reduction of acetophenones Jack Liang, Stephane J. Jenne, Emily Mundorff, Charlene Ching, Anke Krebber +1 more 2018-04-24 $7,116,000
9873863 Polynucleotides encoding ketoreductase polypeptides for reduction of acetophenones Jack Liang, Stephane J. Jenne, Emily Mundorff, Charlene Ching, Anke Krebber +1 more 2018-01-23 $4,594,000
9657320 Engineered ketoreductase polypeptides Christopher Savile, Emily Mundorff, Gjalt W. Huisman, Steven J. Collier 2017-05-23 $2,131,000
9528131 Methods of using ketoreductase polypeptides for reduction of acetophenones Jack Liang, Stephane J. Jenne, Emily Mundorff, Charlene Ching, Anke Krebber +1 more 2016-12-27 $656,000
9228213 Polynucleotides encoding engineered ketoreductase polypeptides Christopher Savile, Emily Mundorff, Gjalt W. Huisman, Steven J. Collier 2016-01-05 $876,000
8980605 Ketoreductases and uses thereof Charlene Ching, Gjalt W. Huisman, Emily Mundorff, Lisa Marie Newman 2015-03-17 $895,000
8877475 Polynucleotides encoding engineered ketoreductase polypeptides Christopher Savile, Emily Mundorff, Gjalt W. Huisman, Steven J. Collier 2014-11-04 $958,000
8859784 Stereomerically pure fused bicyclic proline compounds useful for preparing hepatitis C protease inhibitors Jack Liang, James Lalonde, Jun Zhu, John D. Munger, Jr. 2014-10-14 $1,902,000
8852909 Ketoreductase polypeptides for the reduction of acetophenones Jack Liang, Stephane J. Jenne, Emily Mundorff, Charlene Ching, Anke Krebber +1 more 2014-10-07 $834,000
8748143 Ketoreductase polypeptides for the reduction of acetophenones Jack Liang, Stephane J. Jenne, Emily Mundorff, Charlene Ching, Anke Krebber +1 more 2014-06-10
8673607 Ketoreductase polypeptides for the production of a 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine Christopher Savile, Emily Mundorff, Gjalt W. Huisman, Steven J. Collier 2014-03-18 $1,153,000
8574876 Biocatalytic processes for the preparation of stereomerically pure fused bicyclic proline compounds Benjamin Mijts, Sheela Muley, Jack Liang, Lisa Marie Newman, Xiyun Zhang +7 more 2013-11-05 $459,000
8512973 Methods of using engineered ketoreductase polypeptides for the stereoselective reduction of acetophenones Jack Liang, Stephane J. Jenne, Emily Mundorff, Charlene Ching, Anke Krebber +1 more 2013-08-20
8426178 Ketoreductase polypeptides for the production of a 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine Christopher Savile, Emily Mundorff, Gjalt W. Huisman, Steven J. Collier 2013-04-23 $1,149,000
8415127 Ketoreductases and uses thereof Charlene Ching, Gjalt W. Huisman, Emily Mundorff, Lisa Marie Newman 2013-04-09 $599,000
8288141 Ketoreductase polypeptides for the production of 3-aryl-3-hydroxypropanamine from a 3-aryl-3-ketopropanamine Christopher Savile, Emily Mundorff, Gjalt W. Huisman, Steven J. Collier 2012-10-16 $1,788,000