| 11964989 |
KRas G12D inhibitors |
Xiaolun Wang, Aaron Craig Burns, James Gail Christensen, John Michael Ketcham, John David Lawson +21 more |
2024-04-23 |
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| 11802127 |
3,4-dihydro-2,7-naphthyridine-1,6(2H,7H)-diones as MEK inhibitors |
Patrick Michael DOERNER BARBOUR, James F. Blake, Mark Laurence Boys, Joshua Ryan Dahlke, Alex Andrew KELLUM +3 more |
2023-10-31 |
$284,263,000 |
| 11780835 |
Pyrazolo[3,4-b]pyridine compounds as inhibitors of TAM and MET kinases |
Ronald Jay Hinklin, Patrick Barbour, Adam Cook, Joshua Ryan Dahlke, John Gaudino +3 more |
2023-10-10 |
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| 11691973 |
3,4-dihydro-2,7-naphthyridine-1,6(2H,7H)-diones as MEK inhibitors |
Patrick Michael DOERNER BARBOUR, James F. Blake, Sydney Taylor BLANCHE, Mark Laurence Boys, Wesley Dewitt CLARK +9 more |
2023-07-04 |
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| 11453683 |
KRas G12D inhibitors |
Xiaolun Wang, Aaron Craig Burns, James Gail Christensen, John Michael Ketcham, John David Lawson +21 more |
2022-09-27 |
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| 11247990 |
Bicyclic fused pyridine compounds as inhibitors of TAM kinases |
Mark Laurence Boys, Adam Cook, John Gaudino, Ronald Jay Hinklin, Ellen Laird +4 more |
2022-02-15 |
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| 11104676 |
Pyrazolo[3,4-b]pyridine compounds as inhibitors of TAM and MET kinases |
Ronald Jay Hinklin, Patrick Barbour, Adam Cook, Joshua Ryan Dahlke, John Gaudino +3 more |
2021-08-31 |
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| 11028093 |
4,6-substituted-pyrazolo[1,5-a]pyrazines as janus kinase inhibitors |
Mark Laurence Boys, Mark Joseph Chicarelli, Jay Bradford Fell, John P. Fischer, John Gaudino +13 more |
2021-06-08 |
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| 10889589 |
Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain |
Steven W. Andrews, James F. Blake, Barbara J. Brandhuber, Julia Haas, Yutong Jiang +4 more |
2021-01-12 |
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| 10851080 |
Methods of treatment using pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds |
Barbara J. Brandhuber, Timothy Kercher, Gabrielle R. Kolakowski, Shannon L. Winski |
2020-12-01 |
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| 10835533 |
1 -((3S,4R)-4-(3-fluorophenyl)-1-(2-methoxyethyl)pyrrolidin-3-yl)-3-(4-methyl-3-(2-methylpyrimidin-5-yl)-1-phenyl-1H-pyrazol-5-yl)urea as a TrkA kinase inhibitor |
Steven W. Andrews, Brian Baer, Zackary Crane, Weidong Liu, Daniel J. Watson |
2020-11-17 |
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| 10758542 |
Substituted pyrazolo[l,5-a]pyrimidine compounds as Trk kinase inhibitors |
Steven W. Andrews, Kevin Ronald Condroski, Julia Haas, Lily Huang, Yutong Jiang +2 more |
2020-09-01 |
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| 10730880 |
4,6-substituted-pyrazolo[1,5-a]pyrazines as Janus kinase inhibitors |
Mark Laurence Boys, Mark Joseph Chicarelli, Jay Bradford Fell, John P. Fischer, John Gaudino +13 more |
2020-08-04 |
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| 10351575 |
Bicyclic urea, thiourea, guanidine and cyanoguanidine compounds useful for the treatment of pain |
Steven W. Andrews, James F. Blake, Barbara J. Brandhuber, Julia Haas, Yutong Jiang +4 more |
2019-07-16 |
$181,993,000 |
| 10323022 |
Pyrrolidinyl urea, pyrrolidinyl thiourea and pyrrolidinyl guanidine compounds as TrkA kinase inhibitors |
Steven W. Andrews, James F. Blake, Kevin Ronald Condroski, Julia Haas, Lily Huang +4 more |
2019-06-18 |
$181,885,000 |
| 10251889 |
Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors |
Steven W. Andrews, Kevin Ronald Condroski, Julia Haas, Lily Huang, Yutong Jiang +2 more |
2019-04-09 |
$55,361,000 |
| 10189845 |
4,6-substituted-pyrazolo[1,5-a]pyrazines as janus kinase inhibitors |
Mark Laurence Boys, Mark Joseph Chicarelli, Jay Bradford Fell, John P. Fischer, John Gaudino +13 more |
2019-01-29 |
$44,601,000 |
| 10017482 |
Mitotic kinesin inhibitors and methods of use thereof |
Jeremy Hans, Eli M. Wallace, Qian Zhao, Joseph P. Lyssikatos, Thomas D. Aicher +2 more |
2018-07-10 |
$44,836,000 |
| 9896435 |
N-pyrrolidinyl,N′-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors |
Barbara J. Brandhuber, Timothy Kercher, Gabrielle R. Kolakowski, Shannon L. Winski |
2018-02-20 |
$52,853,000 |
| 9878997 |
Pyrrolidinyl urea, pyrrolidinyl thiourea and pyrrolidinyl guanidine compounds as TrkA kinase inhibitors |
Steven W. Andrews, James F. Blake, Kevin Ronald Condroski, Julia Haas, Lily Huang +4 more |
2018-01-30 |
$45,776,000 |
| 9828360 |
Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors |
Steven W. Andrews, James F. Blake, Barbara J. Brandhuber, Kevin Ronald Condroski, Julia Haas +4 more |
2017-11-28 |
$29,519,000 |
| 9822118 |
Bicyclic heteroaryl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors |
Barbara J. Brandhuber, Kevin Ronald Condroski, Lily Huang, Timothy Kercher, Shannon L. Winski |
2017-11-21 |
$29,977,000 |
| 9796724 |
Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors |
Steven W. Andrews, Kevin Ronald Condroski, Julia Haas, Lily Huang, Yutong Jiang +2 more |
2017-10-24 |
$9,622,000 |
| 9790178 |
Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors |
Steven W. Andrews, James F. Blake, Barbara J. Brandhuber, Yutong Jiang, Timothy Kercher +1 more |
2017-10-17 |
$7,871,000 |
| 9782415 |
Substituted pyrazolo[1,5-a]pyrimidine compounds as Trk kinase inhibitors |
Steven W. Andrews, Kevin Ronald Condroski, Julia Haas, Lily Huang, Yutong Jiang +2 more |
2017-10-10 |
$17,115,000 |
