Issued Patents All Time
Showing 126–150 of 191 patents
| Patent # | Title | Co-Inventors | Date |
|---|---|---|---|
| 9370582 | Carbohydrate conjugates as delivery agents for oligonucleotides | Muthiah Manoharan, Jayaprakash K. Nair, Martin Maier | 2016-06-21 |
| 9352048 | Carbohydrate conjugates as delivery agents for oligonucleotides | Muthiah Manoharan, Jayaprakash K. Nair, Martin Maier | 2016-05-31 |
| 9345780 | Site specific delivery of nucleic acids by combining targeting ligands with endosomolytic components | Muthiah Manoharan, David Butler, Muthusamy Jayaraman | 2016-05-24 |
| 9315813 | Compositions and methods for inhibition of expression of apolipoprotein C-III (APOC3) genes | Brian Bettencourt, Kevin Fitzgerald, Stuart Milstein, Martin Maier, Klaus Charisse +3 more | 2016-04-19 |
| 9290760 | Modified iRNA agents | Tracy Zimmermann, Muthiah Manoharan, Martin Maier, Kevin Fitzgerald | 2016-03-22 |
| 9254327 | Methods and compositions for delivery of active agents | Muthiah Manoharan | 2016-02-09 |
| 9249415 | Complement component C5 iRNA compositions and methods of use thereof | Kevin Fitzgerald, James Butler, Brian Bettencourt, Anna Borodovsky, Satyanarayana Kuchimanchi +4 more | 2016-02-02 |
| 9228188 | Compositions and method for inhibiting hepcidin antimicrobial peptide (HAMP) or HAMP-related gene expression | Brian Bettencourt, Akin Akinc, Alfica Sehgal, Don Foster, Stuart Milstein +3 more | 2016-01-05 |
| 9222091 | Therapeutic compositions | Muthiah Manoharan, David Bumcrot | 2015-12-29 |
| 9220683 | Lipids and compositions for the delivery of therapeutics | Muthiah Manoharan, David Butler, Jayaprakash K. Narayanannair, Muthusamy Jayaraman, Laxmab Eltepu | 2015-12-29 |
| 9186325 | Lipids and compositions for the delivery of therapeutics | Muthiah Manoharan, Muthusamy Jayaraman, Laxman Eltepu, Steven M. Ansell, Jianxin Chen | 2015-11-17 |
| 9156873 | Modified 5′ diphosphate nucleosides and oligomeric compounds prepared therefrom | Thazha P. Prakash, Punit P. Seth, Muthiah Manoharan, Eric E. Swayze, Ivan Zlatev | 2015-10-13 |
| 9127274 | Serpinc1 iRNA compositions and methods of use thereof | Akin Akinc, Alfica Sehgal, Ivanka Toudjarska, Donald C. Foster, Stuart Milstein +5 more | 2015-09-08 |
| 9102938 | 2′ and 5′ modified monomers and oligonucleotides | Muthiah Manoharan, Eric E. Swayze, Thazha P. Prakash | 2015-08-11 |
| 9068184 | Compositions and methods for inhibition of expression of protein C (PROC) genes | Ivanka Toudjarska, John M. Maraganore, Brian Bettencourt, Stuart Milstein, Martin Maier +2 more | 2015-06-30 |
| 9061063 | Biodegradable lipids for the delivery of active agents | Martin Maier, Muthusamy Jayaraman, Akin Akinc, Shigeo Matsuda, Pachamuthu Kandasamy +1 more | 2015-06-23 |
| 9012498 | Biodegradable lipids for the delivery of active agents | Muthiah Manoharan, Martin Maier, Muthusamy Jayaraman, Shigeo Matsuda, Narayanannair K. Jayaprakash +2 more | 2015-04-21 |
| 8999351 | Lipids and compositions for the delivery of therapeutics | Muthiah Manoharan, Muthusamy Jayaraman, David Butler, Jayaprakash K. Narayanannair, Martin Maier +1 more | 2015-04-07 |
| 8993746 | Nuclease resistant double-stranded ribonucleic acid | Hans-Peter Vornlocher, Ingo Roehl, Philipp Hadwiger, Tracy Zimmermann, Muthiah Manoharan +1 more | 2015-03-31 |
| 8975389 | Nucleic acid chemical modifications | Muthiah Manoharan, Alexander V. Kelin, Sudhakar Rao Takkellapati, Shigeo Matsuda | 2015-03-10 |
| 8962580 | Chemical modifications of monomers and oligonucleotides with cycloaddition | Muthiah Manoharan, Takeshi Yamada, David Butler, Narayanannair K. Jayaprakash, Muthusamy Jayaraman +3 more | 2015-02-24 |
| 8957223 | Ligand-conjugated monomers | Muthiah Manoharan, Venkitasamy Kesavan | 2015-02-17 |
| 8927513 | 5′ phosphate mimics | Muthiah Manoharan, Marija Prhavc, Ivan Zlatev | 2015-01-06 |
| 8883202 | Lipid compositions | Muthiah Manoharan, Muthusamy Jayaraman, David Butler, Michael E. Jung | 2014-11-11 |
| 8865677 | iRNA agents with biocleavable tethers | Muthiah Manoharan | 2014-10-21 |