| 9814777 |
Targeting lipids |
Muthiah Manoharan, Jayaprakash K. Nair, Muthusamy Jayaraman |
2017-11-14 |
| 9796974 |
Modified RNAi agents |
Tracy Zimmermann, Muthiah Manoharan, Martin Maier, Satyanarayana Kuchimanchi, Klaus Charisse |
2017-10-24 |
| 9783806 |
TMPRSS6 iRNA compositions and methods of use thereof |
James Butler, Brian Bettencourt, Martin Maier, Klaus Charisse |
2017-10-10 |
| 9764036 |
Lipids and compositions for the delivery of therapeutics |
Muthiah Manoharan, David Butler, Jayaprakash K. Nair, Muthusamy Jayaraman, Laxman Eltepu |
2017-09-19 |
| 9725479 |
5′-end derivatives |
Muthiah Manoharan, Ivan Zlatev, Eric E. Swayze, Thazha P. Prakash, Walter F. Lima |
2017-08-08 |
| 9725718 |
Compositions and methods for inhibition of expression of protein C (PROC) genes |
Ivanka Toudjarska, John M. Maraganore, Brian Bettencourt, Stuart Milstein, Martin Maier +2 more |
2017-08-08 |
| 9708607 |
Modified RNAi agents |
Muthiah Manoharan |
2017-07-18 |
| 9707292 |
Lipids and compositions for the delivery of therapeutics |
Muthiah Manoharan, Muthusamy Jayaraman, Laxman Eltepu, Steven M. Ansell, Jianxin Chen |
2017-07-18 |
| 9708615 |
Therapeutic compositions |
Muthiah Manoharan, David Bumcrot |
2017-07-18 |
| 9701963 |
Complement component C5 iRNA compositions and methods of use thereof |
Kevin Fitzgerald, James Butler, Brian Bettencourt, Anna Borodovsky, Satyanarayana Kuchimanchi +4 more |
2017-07-11 |
| 9701623 |
Di-aliphatic substituted pegylated lipids |
Muthiah Manoharan, Jayaprakash K. Nair, Muthusamy Jayaraman, Satoru Matsumoto |
2017-07-11 |
| 9694077 |
Lipid compositions |
Muthiah Manoharan, Muthusamy Jayaraman, David Butler, Michael E. Jung |
2017-07-04 |
| 9687550 |
Compositions for nucleic acid delivery |
Muthiah Manoharan, Muthusamy Jayaraman, David Butler, Mamta Kapoor, Rajesh Kumar Kainthan |
2017-06-27 |
| 9682922 |
Biodegradable lipids for the delivery of active agents |
Muthiah Manoharan, Martin Maier, Muthusamy Jayaraman, Shigeo Matsuda, Jayaprakash K. Nair +2 more |
2017-06-20 |
| 9682139 |
Lipids and compositions for the delivery of therapeutics |
Muthiah Manoharan, Muthusamy Jayaraman, David Butler, Jayaprakash K. Nair, Martin Maier +1 more |
2017-06-20 |
| 9574192 |
Serapina1 iRNA compositions and methods of use thereof |
Alfica Sehgal, Klaus Charisse, Brian Bettencourt, Martin Maier, Gregory Hinkle +1 more |
2017-02-21 |
| 9512164 |
Oligonucleotide end caps |
Muthiah Manoharan |
2016-12-06 |
| 9476045 |
iRNA agents with biocleavable tethers |
Muthiah Manoharan |
2016-10-25 |
| 9453043 |
Nucleic acid chemical modifications |
Muthiah Manoharan, Alexander V. Kelin, Sudhakar Rao Takkellapati, Shigeo Matsuda |
2016-09-27 |
| 9453222 |
Ligand-conjugated monomers |
Muthiah Manoharan, Venkitasamy Kesavan |
2016-09-27 |
| 9399775 |
RNAi agents, compositions and methods of use thereof for treating transthyretin (TTR) associated diseases |
Tracy Zimmermann, Muthiah Manoharan, Martin Maier, Satyanarayana Kuchimanchi, Klaus Charisse |
2016-07-26 |
| 9394234 |
Lipid formulations |
Jianxin Chen, Steven M. Ansell, Akin Akinc, Joseph R. Dorkin, Xiaojun Qin +4 more |
2016-07-19 |
| 9394540 |
Modified iRNA agents |
Muthiah Manoharan, Venkitasamy Kesavan |
2016-07-19 |
| 9376680 |
Serpinc1 iRNA compositions and methods of use thereof |
Akin Akinc, Alfica Sehgal, Ivanka Toudjarska, Donald C. Foster, Stuart Milstein +5 more |
2016-06-28 |
| 9370581 |
Carbohydrate conjugates as delivery agents for oligonucleotides |
Muthiah Manoharan, Jayaprakash K. Nair, Martin Maier |
2016-06-21 |