Issued Patents All Time
Showing 25 most recent of 33 patents
| Patent # | Title | Co-Inventors | Date |
|---|---|---|---|
| 12275716 | Modulators of estrogen receptor proteolysis and associated methods of use | Andrew P. Crew, Hanqing Dong, Keith R. Hornberger, Yimin Qian, Jing Wang | 2025-04-15 |
| 12264157 | Compounds and methods for the enhanced degradation of targeted proteins | Andrew P. Crew, Xin Chen, Hanqing Dong, Caterina Ferraro, Yimin Qian +6 more | 2025-04-01 |
| 12239711 | Cereblon ligands and bifunctional compounds comprising the same | Andrew P. Crew, Hanqing Dong, Keith R. Hornberger, Yimin Qian, Lawrence B. Snyder +1 more | 2025-03-04 |
| 12171831 | Compounds and methods for the targeted degradation of bromodomain- containing proteins | Yimin Qian, Hanqing Dong, Jing Wang, Michael Berlin, Andrew P. Crew | 2024-12-24 |
| 11986531 | Compounds and methods for the targeted degradation of rapidly accelerated fibrosarcoma polypeptides | Andrew P. Crew, Keith R. Hornberger, Jing Wang, Saul Jaime-Figueroa, Hanqing Dong +1 more | 2024-05-21 |
| 11834460 | Imide-based modulators of proteolysis and associated methods of use | George Burslem, Philipp M. Cromm, Saul Jaime-Figueroa, Momar Toure | 2023-12-05 |
| 11554171 | Compounds and methods for the targeted degradation of bromodomain-containing proteins | Yimin Qian, Hanqing Dong, Jing Wang, Michael Berlin, Andrew P. Crew | 2023-01-17 |
| 11512083 | Compounds and methods for the enhanced degradation of targeted proteins | Andrew P. Crew, Xin Chen, Hanqing Dong, Caterina Ferraro, Yimin Qian +5 more | 2022-11-29 |
| 11220515 | Imide-based modulators of proteolysis and associated methods of use | George Burslem, Philipp M. Cromm, Saul Jaime-Figueroa, Momar Toure | 2022-01-11 |
| 11028088 | Modulators of BTK proteolysis and methods of use | Saul Jaime-Figueroa, Momar Toure | 2021-06-08 |
| 10994015 | EGFR proteolysis targeting chimeric molecules and associated methods of use | Andrew P. Crew, Kurt Zimmermann, Jing Wang, Saul Jaime-Figueroa, George Burslem | 2021-05-04 |
| 10806737 | Compounds and methods for the targeted degradation of fetal liver kinase polypeptides | Andrew P. Crew, Keith R. Hornberger, George Burslem | 2020-10-20 |
| 10772962 | Compounds and methods for the targeted degradation of bromodomain-containing proteins | Yimin Qian, Hanqing Dong, Jing Wang, Michael Berlin, Andrew P. Crew | 2020-09-15 |
| RE48175 | Hydrophobically tagged small molecules as inducers of protein degradation | Nathanael S. Gray, Ting Xie, Sang-Min Lim, Pasi Janne | 2020-08-25 |
| 10730862 | Compounds and methods for the enhanced degradation of targeted proteins and other polypeptides by an E3 ubiquitin ligase | Dennis Buckley, Alessio Ciulli, William L. Jorgensen, Peter Gareiss, Inge Van Molle +10 more | 2020-08-04 |
| 10730870 | Compounds and methods for the enhanced degradation of targeted proteins | Andrew P. Crew, Xin Chen, Hanqing Dong, Caterina Ferraro, Yimin Qian +6 more | 2020-08-04 |
| 10723717 | Compounds and methods for the targeted degradation of rapidly accelerated fibrosarcoma polypeptides | Andrew P. Crew, Keith R. Hornberger, Jing Wang, Hanqing Dong, Yimin Qian +1 more | 2020-07-28 |
| 10604506 | Modulators of estrogen receptor proteolysis and associated methods of use | Andrew P. Crew, Keith R. Hornberger, Hanqing Dong, Jing Wang, Yimin Qian | 2020-03-31 |
| 10145848 | Small-molecule hydrophobic tagging of fusion proteins and induced degradation of same | Hyun Seop Tae, Ashley R. Schneekloth, Taavi Neklesa, Thomas Sundberg | 2018-12-04 |
| 10071164 | Estrogen-related receptor alpha based protac compounds and associated methods of use | Andrew P. Crew, Hanqing Dong, Eunhwa Ko, Jing Wang | 2018-09-11 |
| 9938264 | Proteolysis targeting chimera compounds and methods of preparing and using same | Momar Toure, Eunhwa Ko, Saul Jaime-Figueroa | 2018-04-10 |
| 9758522 | Hydrophobically tagged small molecules as inducers of protein degradation | Nathanael S. Gray, Ting Xie, Sang-Min Lim, Pasi Janne | 2017-09-12 |
| 9632089 | Small-molecule hydrophobic tagging of fusion proteins and induced degradation of same | Hyun Seop Tae, Ashley R. Schneekloth, Taavi Neklesa, Thomas Sundberg | 2017-04-25 |
| 9500653 | Small-molecule hydrophobic tagging of fusion proteins and induced degradation of same | Hyun Seop Tae, Ashley R. Schneekloth, Taavi Neklesa, Thomas Sundberg | 2016-11-22 |
| 8324174 | Compounds for enzyme inhibition | Mark S. Smyth, Guy J. Laidig, Ronald T. Borchardt, Barry A. Bunin, John H. Musser | 2012-12-04 |