Issued Patents All Time
Showing 1–25 of 28 patents
| Patent # | Title | Co-Inventors | Date |
|---|---|---|---|
| 12023385 | Tunable endogenous protein degradation with heterobifunctional compounds | Georg Winter, Andrew J. Phillips, Timothy Heffernan, James E. Bradner, Justin Roberts +1 more | 2024-07-02 |
| 11944625 | Calmodulin inhibitors, Chk2 inhibitors and RSK inhibitors for the treatment of ribosomal disorders and ribosomapathies | James E. Bradner, Jun Qi, Leonard I. Zon, Elizabeth MACARI | 2024-04-02 |
| 11583586 | Methods to induce targeted protein degradation through bifunctional molecules | James E. Bradner, Georg Winter | 2023-02-21 |
| 11578075 | Degradation of protein kinases by conjugation of protein kinase inhibitors with E3 ligase ligand and methods of use | James E. Bradner, Mette Ishoey ROSENBAUM, Georg Winter | 2023-02-14 |
| 11311609 | Regulating chimeric antigen receptors | James E. Bradner, Justin Roberts, Behnam Nabet, Georg Winter, Andrew J. Phillips +1 more | 2022-04-26 |
| 11306105 | Cyano thienotriazolodiazepines and uses thereof | James E. Bradner, Jun Qi, Minoru Tanaka | 2022-04-19 |
| 11293023 | Tunable endogenous protein degradation | Georg Winter, Andrew J. Phillips, Timothy Heffernan, James E. Bradner, Justin Roberts +1 more | 2022-04-05 |
| 11285218 | Degradation of bromodomain-containing protein 9 (BRD9) by conjugation of BRD9 inhibitors with E3 ligase ligand and methods of use | James E. Bradner, David Ian Remillard | 2022-03-29 |
| 11059801 | Methods to induce targeted protein degradation through bifunctional molecules | James E. Bradner, Georg Winter | 2021-07-13 |
| 11046954 | Targeted protein degradation to attenuate adoptive T-cell therapy associated adverse inflammatory responses | James E. Bradner, Justin Roberts, Behnam Nabet, Georg Winter, Andrew J. Phillips +1 more | 2021-06-29 |
| 10980808 | Calmodulin inhibitors, Chk2 inhibitors and RSK inhibitors for the treatment of ribosomal disorders and ribosomapathies | James E. Bradner, Jun Qi, Leonard I. Zon, Elizabeth MACARI | 2021-04-20 |
| 10925868 | Degradation of protein kinases by conjugation of protein kinase inhibitors with E3 ligase ligand and methods of use | Nathanael S. Gray, James E. Bradner, Li Tan, Hai-Tsang Huang, Georg Winter +1 more | 2021-02-23 |
| 10899768 | Degradation of protein kinases by conjugation of protein kinase inhibitors with E3 ligase ligand and methods of use | James E. Bradner, Mette Ishoey ROSENBAUM, Georg Winter | 2021-01-26 |
| 10849980 | Methods to induce targeted protein degradation through bifunctional molecules | James E. Bradner, Georg Winter | 2020-12-01 |
| 10793571 | Uses of diazepane derivatives | James E. Bradner, Nathanael S. Gray, Jun Qi, Michael R. McKeown | 2020-10-06 |
| 10730862 | Compounds and methods for the enhanced degradation of targeted proteins and other polypeptides by an E3 ubiquitin ligase | Craig M. Crews, Alessio Ciulli, William L. Jorgensen, Peter Gareiss, Inge Van Molle +10 more | 2020-08-04 |
| 10702504 | Degradation of tripartite motif-containing protein 24 (TRIM24) by conjugation of TRIM24 inhibitors with E3 ligase ligand and methods of use | James E. Bradner, Lara Nicole Gechijian | 2020-07-07 |
| 10669253 | Methods to induce targeted protein degradation through bifunctional molecules | James E. Bradner, Georg Winter | 2020-06-02 |
| 10464925 | Methods to induce targeted protein degradation through bifunctional molecules | James E. Bradner, Georg Winter | 2019-11-05 |
| 10308653 | Diazepane derivatives and uses thereof | James E. Bradner | 2019-06-04 |
| 10239888 | Targeted protein degradation using a mutant E3 ubiquitin ligase | James E. Bradner, Mette Ishoey, Joshiawa Paulk, Marc A. Cohen, Rhamy Zeid | 2019-03-26 |
| 10125114 | Methods to induce targeted protein degradation through bifunctional molecules | James E. Bradner, Georg Winter | 2018-11-13 |
| 9951074 | Dihydropteridinone derivatives and uses thereof | James E. Bradner | 2018-04-24 |
| 9821068 | Methods to induce targeted protein degradation through bifunctional molecules | James E. Bradner, Georg Winter | 2017-11-21 |
| 9770512 | Methods to induce targeted protein degradation through bifunctional molecules | James E. Bradner, Georg Winter | 2017-09-26 |