Issued Patents All Time
Showing 1–25 of 37 patents
| Patent # | Title | Co-Inventors | Date |
|---|---|---|---|
| 12398097 | WDR5-MYC inhibitors | William P. Tansey, Stephen W. Fesik, Alex G. Waterson, Changho Han, Joseph R. Alvarado +4 more | 2025-08-26 |
| 12384751 | Allosteric activators of the ALPHA1A-adrenergic receptor | Dianne M. Perez, Jonathan D. Macdonald | 2025-08-12 |
| 11999716 | WDR5 inhibitors and modulators | Taekyu Lee, Joseph R. Alvarado, Jianhua Tian, Kenneth M. Meyers, Changho Han +4 more | 2024-06-04 |
| 10844044 | WDR5 inhibitors and modulators | Joseph R. Alvarado, Rocco D. Gogliotti, Changho Han, Kenneth M. Meyers, Jianhua Tian +3 more | 2020-11-24 |
| 10807959 | WDR5-MLL1 inhibitors and modulators | Rocco D. Gogliotti, KyuOk Jeon, James M. Salovich, Jonathan D. Macdonald, Jonathan Mills +5 more | 2020-10-20 |
| 10501466 | WDR5 inhibitors and modulators | Stephen W. Fesik, James M. Salovich, William P. Tansey, Feng Wang, Jason Phan +1 more | 2019-12-10 |
| 10160763 | WDR5 inhibitors and modulators | Stephen W. Fesik, William P. Tansey, Edward T. Olejniczak, Jason Phan, Feng Wang +2 more | 2018-12-25 |
| 9963466 | Substituted 5-membered heterocyclic analogs as protease activated receptor 4 (PAR-4) antagonists | Heidi E. Hamm, Craig W. Lindsley, Matthew T. Duvernay, Kayla J. Temple | 2018-05-08 |
| 9708278 | Substituted 4-benzyl-3,4-dihydro-2H-benzo[B][1,4]oxazine-2-carboxamide analogs as positive allosteric modulators of muscarinic acetycholine receptor M1 | Craig W. Lindsley, P. Jeffrey Conn, Joseph Panarese | 2017-07-18 |
| 9572794 | Substituted indoles as selective protease activated receptor 4 (PAR-4) antagonists | Heidi E. Hamm, Craig W. Lindsley, Wandong Wen, Summer E. Young, Matthew T. Duvernay +1 more | 2017-02-21 |
| 9540371 | Substituted quinazolin-4(3H)-ones, pyrido[3,4-d]pyrimidin-4(3H)-ones, pyrido[3,2-d]pyrimidin-4(3H)-ones and pyrido[2,3-d]pyrimidin-4(3H)-ones as positive allosteric modulators of muscarinic acetycholine receptor M1 | Craig W. Lindsley, P. Jeffrey Conn, Joseph Panarese | 2017-01-10 |
| 9527834 | Substituted 1-benzylquinoxalin-2(1H)-one analogs as positive allosteric modulators of muscarinic acetylcholine receptor M1 | Craig W. Lindsley, P. Jeffrey Conn, Joseph Panarese | 2016-12-27 |
| 9255103 | Substituted pyrazolo[1,5-a]pyrazines as mGluR5 receptor modulators | P. Jeffrey Conn, Craig W. Lindsley, José Manuel Bartolomé-Nebreda, Susana Conde-Ceide, Gregor James MacDonald +2 more | 2016-02-09 |
| 9238647 | P2X3 receptor antagonists for treatment of pain | Christopher S. Burgey, Zhengwu J. Deng, Diem N. Nguyen, Daniel V. Paone, Craig M. Potteiger +3 more | 2016-01-19 |
| 9212180 | Menin-MLL inhibitors and methods of use thereof | Jolanta Grembecka, Tomasz Cierpicki, Sunil Kumar Upadhyay, Rocco D. Gogliotti, Timothy J. Senter | 2015-12-15 |
| 9090632 | Bicyclic oxazole and thiazole compounds and their use as allosteric modulators of mGluR5 receptors | P. Jeffrey Conn, Craig W. Lindsley, Carrie K. Jones, José Manuel Bartolomé-Nebreda, Susana Conde-Ceide +2 more | 2015-07-28 |
| 9029366 | Substituted bicyclic alkoxy pyrazole analogs as allosteric modulators of mGluR5 receptors | P. Jeffrey Conn, Craig W. Lindsley, José Manuel Bartolomé-Nebreda, Susana Conde-Ceide, Gregor James MacDonald +4 more | 2015-05-12 |
| 8969389 | Substituted 6-methylnicotinamides as mGluR5 positive allosteric modulators | P. Jeffrey Conn, Craig W. Lindsley, Ya Zhou, Jason Manka, Gregor McDonald +1 more | 2015-03-03 |
| 8901125 | Substituted bicyclic alkoxy pyrazole analogs as allosteric modulators of mGluR5 receptors | P. Jeffrey Conn, Craig W. Lindsley, José Manuel Bartolomé-Nebreda, Susana Conde-Ceide, Gregor James MacDonald +4 more | 2014-12-02 |
| 8865725 | Substituted imidazopyrimidin-5(6H)-ones as allosteric modulators of MGLUR5 receptors | P. Jeffrey Conn, Craig W. Lindsley, José Manuel Bartolomé-Nebreda, Gregor James MacDonald, Susana Conde-Ceide +3 more | 2014-10-21 |
| 8853237 | Naphthyridinone analogs as mGluR5 positive allosteric modulators | P. Jeffrey Conn, Craig W. Lindsley, Jason Manka, Jon Jacobs, Ya Zhou +4 more | 2014-10-07 |
| 8710074 | Dihydronaphthyridinyl(organo)methanone analogs as positive allosteric mGluR5 modulators | P. Jeffrey Conn, Craig W. Lindsley, Jason Manka, Jon Jacobs, Ya Zhou +4 more | 2014-04-29 |
| 8703946 | Substituted pyrazolo[1,5-A]pyrazine compounds as allosteric modulators of mGluR5 receptors | P. Jeffrey Conn, Craig W. Lindsley, Carrie K. Jones, José Manuel Bartolomé-Nebreda, Gregor McDonald +2 more | 2014-04-22 |
| 8592422 | Bicyclic triazole and pyrazole lactams as allosteric modulators of mGluR5 receptors | P. Jeffrey Conn, Craig W. Lindsley, José Manuel Bartolomé-Nebreda, Susana Conde-Ceide, Gregor James MacDonald +5 more | 2013-11-26 |
| 8399473 | Macrocyclic spiropiperidine beta-secretase inhibitors for the treatment of Alzheimer's disease | Philippe G. Nantermet, M. Katharine Holloway, Keith P. Moore | 2013-03-19 |