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Patent Leaderboard
USPTO Patent Rankings Data through Dec 31, 2025
Home › Technologies › Biotechnology and fermentation

Biotechnology and fermentation Patent Leaders in 2016 2016

Primary CPC class C12 · Section C

Rankings count each patent once by its primary Cooperative Patent Classification. All-time pages aggregate the full database; year pages use patent grant year.

Recent years: 2016201720182019202020212022202320242025

Patents per Year

Patents granted per year, 1996 to 2025Bar chart with a peak of 4,888 patents in 2020.peak 4,8881996: 1,464 patents19961997: 1,984 patents1998: 2,885 patents1999: 3,015 patents19992000: 2,651 patents2001: 3,139 patents2002: 2,780 patents20022003: 2,530 patents2004: 2,121 patents2005: 1,894 patents20052006: 2,410 patents2007: 2,407 patents2008: 2,171 patents20082009: 2,314 patents2010: 3,158 patents2011: 3,235 patents20112012: 3,506 patents2013: 3,598 patents2014: 4,133 patents20142015: 4,137 patents2016: 4,240 patents2017: 4,377 patents20172018: 4,522 patents2019: 4,761 patents2020: 4,888 patents20202021: 4,447 patents2022: 4,121 patents2023: 3,845 patents20232024: 3,917 patents2025: 4,134 patents2025

Top Inventors

Rank ↑ Inventor ↕ Patents ↕ Primary Company ↕
1 Steven J. Collier 16 Codexis
2 Marshall Medoff 15 Xyleco
3 Susan M. Freier 14 Ionis Pharmaceuticals
#4 Sara Landvik 13 Novozymes A/S
#5 Thomas W. Myers 13 Roche Molecular Systems
#6 Derek Smith 12 Codexis
#7 Keith Bauer 12 Roche Molecular Systems
#8 Malek Faham 12 Adaptive Biotechnologies
#9 Hongxian He 11 E.I. Du Pont De Nemours And
#10 Kallanthottathil G. Rajeev 11 Alnylam Pharmaceuticals
#11 Lisbeth Kalum 11 Novozymes A/S
#12 Andrew J. Murphy 10 Regeneron Pharmaceuticals
#13 Emily Mundorff 10 Codexis
#14 Fred Reichert 10 Roche Molecular Systems
#15 George Rudenko 10 Solazyme
#16 Joseph Collard 10 Curna
#17 Lars Henrik Oestergaard 10 Novozymes A/S
#18 Lynn Macdonald 10 Regeneron Pharmaceuticals
#19 Mark S. Payne 10 E.I. Du Pont De Nemours And
#20 Muthiah Manoharan 10 Alnylam Pharmaceuticals
#21 Olga Khorkova Sherman 10 —
#22 Scott Franklin 10 Solazyme
#23 Sean Stevens 10 Regeneron Pharmaceuticals
#24 Thomas Craig Masterman 10 Xyleco
#25 Anthony P. Burgard 9 Genomatica
#26 Aravind Somanchi 9 Solazyme
#27 C. Frank Bennett 9 Isis Pharmaceuticals
#28 David M. Valenzuela 9 Regeneron Pharmaceuticals
#29 Frances H. Arnold 9 Caltech
#30 Fyodor Urnov 9 Sangamo Biosciences
#31 Jonathan M. Rothberg 9 Thermo Fisher
#32 Kai Qin Lao 9 Thermo Fisher
#33 Michael Koepke 9 Lanzatech New Zealand Limited
#34 Stephen R. Quake 9 Caltech
#35 Xiyun Zhang 9 Codexis
#36 Bert Vogelstein 8 The Johns Hopkins University
#37 Carsten Andersen 8 Novozymes A/S
#38 Jörg Bauer 8 Basf Plant Science Company Gmbh
#39 Kenneth W. Kinzler 8 The Johns Hopkins University
#40 Lori Ann Maggio-Hall 8 Butamax Advanced Biofuels
#41 Merja Penttila 8 Teknologian Tutkimuskeskus Vtt Oy
#42 Radoje Drmanac 8 Complete Genomics
#43 Thomas Scholz 8 E.I. Du Pont De Nemours And
#44 Yefim Brun 8 E.I. Du Pont De Nemours And
#45 Allan Svendsen 7 Novozymes A/S
#46 Anastasia Khvorova 7 Dharmacon
#47 Carlo M. Croce 7 Ohio State University
#48 Carl H. June 7 University of Pennsylvania
#49 Edward J. Rebar 7 Sangamo Therapeutics
#50 George D. Yancopoulos 7 Regeneron Pharmaceuticals
#51 Gjalt W. Huisman 7 Codexis
#52 Jeffrey C. Miller 7 Sangamo Therapeutics
#53 John J. Rossi 7 City Of Hope
#54 Justin M. Lira 7 Dow Agrosciences
#55 Mark Aaron Behlke 7 Integrated Dna Technologies
#56 Mark J. Burk 7 Genomatica
#57 Masaru Takagi 7 Kyocera Document Solutions
#58 Nancy Schoenbrunner 7 Roche Molecular Systems
#59 Priti Pharkya 7 Genomatica
#60 Shiwei Song 7 Codexis
#61 Stanislaw Flasinski 7 Monsanto Technology
#62 Stephen Turner 7 Pacific Biosciences Of California
#63 Thomas Willis 7 Adaptive Biotechnologies
#64 Alireza Rezania 6 Johnson & Johnson
#65 Andrew C. Eliot 6 Butamax Advanced Biofuels
#66 Aris N. Economides 6 Regeneron Pharmaceuticals
#67 Axel Scherer 6 Caltech
#68 Balkrishen Bhat 6 Isis Pharmaceuticals
#69 Bin Li 6 Thermo Fisher
#70 Brian Bettencourt 6 Alnylam Pharmaceuticals
#71 Caroline M. Peres 6 Danisco Us
#72 Chikara Ohto 6 Toyota
#73 Christopher Rohde 6 Factor Bioscience
#74 David N. Thompson 6 Battelle Energy Alliance
#75 Debbie Yaver 6 Novozymes
#76 Elena Feinstein 6 Quark Pharmaceuticals
#77 Feng Xu 6 Merck
#78 Hagai Karchi 6 Evogene
#79 Jennifer O'Neil 6 Thermo Fisher
#80 Jonas Korlach 6 Pacific Biosciences Of California
#81 Kristine Sorensen 6 Heliae Development
#82 Laura Carney 6 Heliae Development
#83 Lance E. Steward 6 AbbVie
#84 Matthew Angel 6 Factor Bioscience
#85 Margaret Karow 6 Regeneron Pharmaceuticals
#86 Martin Maier 6 Alnylam Pharmaceuticals
#87 Mark J. Nelson 6 Butamax Advanced Biofuels
#88 Norihiro Mitsukawa 6 Toyota
#89 Oscar Alvizo 6 Codexis
#90 Philip J. Lee 6 Emd Millipore
#91 Rachel Kasinskas 6 Thermo Fisher
#92 Richard R. Bott 6 Danisco Us
#93 Robin E. Osterhout 6 Genomatica
#94 Sheng Ding 6 Scripps Research
#95 Stuart Milstein 6 Alnylam Pharmaceuticals
#96 Aaron T. Woosley 5 Dow Agrosciences
#97 Andrew E. Robinson 5 Dow Agrosciences
#98 Bob D. Brown 5 Dicerna Pharmaceuticals
#99 Bruce L. Levine 5 University of Pennsylvania
#100 Carsten Sjoeholm 5 Novozymes A/S

Top Companies

Rank ↑ Company ↕ Patents ↕
1 Thermo Fisher 72
2 University of California 66
3 Novozymes A/S 61
#4 Novozymes 41
#5 Stanford University 40
#6 E.I. Du Pont De Nemours And 37
#7 Roche Molecular Systems 37
#8 Codexis 36
#9 Monsanto Technology 36
#10 The Johns Hopkins University 34
#11 Caltech 33
#12 CNRS 27
#13 Dsm Ip Assets B.V. 27
#14 WARF 27
#15 Dow Agrosciences 26
#16 Unknown 25
#17 GE 25
#18 Applied Biosystems 24
#19 Danisco Us 24
#20 MIT 23
#21 Pioneer (Corteva) 23
#22 Butamax Advanced Biofuels 22
#23 Harvard University 21
#24 Sangamo Biosciences 21
#25 University of Pennsylvania 21
#26 Illumina 20
#27 Pacific Biosciences Of California 20
#28 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services 20
#29 USDA 20
#30 Samsung 20
#31 Abbott 18
#32 Ajinomoto Co. 18
#33 Alnylam Pharmaceuticals 17
#34 Basf Plant Science Company Gmbh 16
#35 Cornell University 16
#36 Institut National De La Sante Et De La Recherche Medicale (Inserm) 16
#37 Ionis Pharmaceuticals 16
#38 Syngenta Participations Ag 15
#39 University Of Texas System 15
#40 The General Hospital 15
#41 Xyleco 15
#42 Gen-Probe Incorporated 14
#43 Kyoto University 14
#44 Regeneron Pharmaceuticals 14
#45 Rutgers, The State University Of New Jersey 14
#46 University of Michigan 14
#47 University Of Massachusetts 14
#48 Merck 14
#49 Agency For Science, Technology And Research 13
#50 Bio-Rad Laboratories 13
#51 Illumina Cambridge Limited 13
#52 Kaneka 13
#53 3M 12
#54 Biomerieux 11
#55 City Of Hope 11
#56 Emd Millipore 11
#57 Novartis Ag 11
#58 Qiagen Gmbh 11
#59 Quest Diagnostics Investments 11
#60 Sarepta Therapeutics 11
#61 Columbia University 11
#62 University Of Kentucky 11
#63 Toyota 11
#64 Adaptive Biotechnologies 10
#65 Michigan State University 10
#66 Cargill, Incorporated 10
#67 Cellular Dynamics International 10
#68 Cj Cheiljedang 10
#69 Curna 10
#70 Dupont Nutrition Biosciences Aps 10
#71 Lanzatech New Zealand Limited 10
#72 National Institute Of Advanced Industrial Science And Technology 10
#73 National University Of Singapore 10
#74 Regulus Therapeutics 10
#75 Suntory Holdings Limited 10
#76 Johnson & Johnson 10
#77 Affymetrix 9
#78 Basf Se 9
#79 Complete Genomics 9
#80 Genomatica 9
#81 Ibis Biosciences 9
#82 New England Biolabs 9
#83 Promega 9
#84 Purdue Research Foundation 9
#85 Rijk Zwaan Zaadteelt En Zaadhandel B.V. 9
#86 Sirna Therapeutics 9
#87 The Goodyear Tire & Rubber 9
#88 University of Colorado, A Body Corporate 9
#89 University Of North Carolina At Chapel Hill 9
#90 University Of British Columbia 9
#91 University Of South Florida 9
#92 Academia Sinica 8
#93 Arkray 8
#94 Arrowhead Pharmaceuticals 8
#95 Dana-Farber Cancer Institute 8
#96 Duke University 8
#97 ITRI 8
#98 Intrexon 8
#99 Keygene N.V. 8
#100 KAIST 8