| 11655257 |
MK2 inhibitors, synthesis thereof, and intermediates thereto |
Maryll E. Geherty, Richard M. Heid, Jr., Mohit Atul Kothare, Hon-Wah Man, Alexander L. Ruchelman +3 more |
2023-05-23 |
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| 11312699 |
Processes for preparing 2-(4-chlorophenyl)-N-((2-(2,6-dioxopiperidin-3-yl)-1-oxoisoindolin-5-yl)methyl)-2,2-difluoroacetamide |
Marie Georges Beauchamps, Jianxin Han, Joshua Hansen, Mohit Atul Kothare, Michael James Williams +2 more |
2022-04-26 |
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| 10894796 |
MK2 inhibitors, synthesis thereof, and intermediates thereto |
Maryll E. Geherty, Richard M. Heid, Jr., Mohit Atul Kothare, Hon-Wah Man, Alexander L. Ruchelman +3 more |
2021-01-19 |
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| 9975872 |
Processes for the preparation of (s)-3-(4-((4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione and pharmaceutically acceptable forms thereof |
John F. Traverse, Chengmin Zhang, Benjamin M. Cohen, William W. Leong |
2018-05-22 |
$110,229,000 |
| 9309220 |
Processes for the preparation of (S)-3-(4- (4-(morpholinomethyl)benzyl)oxy)-1-oxoisoindolin-2-yl)piperidine-2,6-dione and pharmaceutically acceptable forms thereof |
John F. Traverse, Chengmin Zhang, Benjamin M. Cohen, William W. Leong |
2016-04-12 |
$278,089,000 |
| 9133161 |
Processes for preparing isoindoline-1,3-dione compounds |
John F. Traverse, Alexander L. Ruchelman, Jihong Liu, Hongfeng Liu, Chengjun Ma +2 more |
2015-09-15 |
$286,222,000 |
| 8445496 |
Crystalline forms of 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile and methods of preparing the same |
Marc Sadler Tesconi, Henry L. Strong, Hong Wen |
2013-05-21 |
|
| 7767678 |
Crystalline forms of 4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-[3-(4-methyl-1-piperazinyl)propoxy]-3-quinolinecarbonitrile and methods of preparing the same |
Marc Sadler Tesconi, Henry L. Strong, Hong Wen |
2010-08-03 |
|
| 7671196 |
Diazepinoquinolines, synthesis thereof, and intermediates thereto |
Sreenivasulu Megati, Anita Wai-Yin Chan |
2010-03-02 |
|
| 7361773 |
Preparation of N1-(2'-pyridyl)-1,2-propanediamine sulfamic acid and its use in the synthesis of biologically active piperazines |
Anita Wai-Yin Chan, Joseph Zeldis, Ivo L. Jirkovsky |
2008-04-22 |
$123,108,000 |
| 7297795 |
Process for preparation of 4-amino-3-quinolinecarbonitriles |
Karen Sutherland, Diane Boschelli, David Blum, Henry L. Strong |
2007-11-20 |
$36,867,000 |
| 7256289 |
Process for making chiral 1,4-disubstituted piperazines |
Ivo L. Jirkovsky, Joseph Zeldis |
2007-08-14 |
$69,730,000 |
| 7166723 |
Process for the synthesis of derivatives of 2,3-dihydro-1,4-dioxino-[2,3-f] quinoline |
Anita Wai-Yin Chan, Timothy T. Curran, Silvio Iera, Warren Chew, John H. Sellstedt +2 more |
2007-01-23 |
$86,239,000 |
| 7091349 |
Process for synthesizing N-aryl piperazines with chiral N′-1-[benzoyl(2-pyridyl)amino]-2-propane substitution |
Joseph Zeldis, Ivo L. Jirkovsky |
2006-08-15 |
$116,757,000 |
| 7038052 |
Process for the synthesis of derivatives of 2, 3-dihydro-1, 4-dioxino- [2, 3-f] quinoline |
Anita Wai-Yin Chan, Timothy T. Curran, Silvio Iera, Warren Chew, John H. Sellstedt +2 more |
2006-05-02 |
$123,270,000 |
| 7019137 |
Process for making chiral 1,4-disubstituted piperazines |
Ivo L. Jirkovsky, Joseph Zeldis |
2006-03-28 |
$49,696,000 |
| 6784294 |
Preparation of N1-(2′-pyridyl)-1,2-propanediamine sulfamic acid and its use in the synthesis of biologically active piperazines |
Anita Wai-Yin Chan, Joseph Zeldis, Ivo L. Jirkovsky |
2004-08-31 |
$69,097,000 |
| 6713626 |
Process for synthesizing N-aryl piperazines with chiral N′-1-[benzoyl(2-pyridyl)amino]-2-propane substitution |
Joseph Zeldis, Ivo L. Jirkovsky |
2004-03-30 |
$80,858,000 |
| 6693197 |
Process for the synthesis of derivatives of 2,3-dihydro-1,4-dioxino- [2,3-f] quinoline |
Anita Wai-Yin Chan, Timothy T. Curran, Silvio Iera, Warren Chew, John H. Sellstedt +2 more |
2004-02-17 |
$179,126,000 |
| 5750735 |
2-thiosubstituted carbapenems |
Yang-I Lin, Panayota Bitha, Subas Sakya, Timothy W. Strohmeyer, Karen Bush +1 more |
1998-05-12 |
|
| 5744465 |
Method of inhibiting a .beta.-lactamase enzyme by administering novel 2-thiosubstituted carbapenems |
Yang-I Lin, Panayota Bitha, Subas Sakya, Timothy W. Strohmeyer, Karen Bush +1 more |
1998-04-28 |
|
| 5700930 |
4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them |
William V. Curran, Carl Bernard Ziegler |
1997-12-23 |
|
| 5656753 |
4-substituted azetidinones as precursors to 2-substituted-3-carboxy carbapenem antibiotics and a method of producing them |
William V. Curran, Carl Bernard Ziegler |
1997-08-12 |
|
| 5623081 |
Method for producing tetrahydrofuranyl compounds |
Yang-I Lin, Panayota Bitha, Subas Sakya, Timothy W. Strohmeyer, Karen Bush +1 more |
1997-04-22 |
|
| 5602118 |
2-thiosubstituted carbapenems |
Yang-I Lin, Panayota Bitha, Subas Sakya, Timothy W. Strohmeyer, Karen Bush +1 more |
1997-02-11 |
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