| 11207312 |
Metallo-beta-lactamase inhibitors and methods of use thereof |
Alexander Pasternak, Shuzhi Dong, Haiqun Tang, Zhiqiang Zhao, Dexi Yang +3 more |
2021-12-28 |
$153,354,000 |
| 10954240 |
Compounds inhibiting leucine-rich repeat kinase enzyme activity |
Xing Dai, Kallol Basu, Duane DeMong, Sarah W. Li, Michael Miller +1 more |
2021-03-23 |
$131,140,000 |
| 10544130 |
Metallo-beta-lactamase inhibitors |
Frank Bennett, Jinlong Jiang, Alexander Pasternak, Shuzhi Dong, Xin Gu +8 more |
2020-01-28 |
$79,189,000 |
| 10329291 |
C5-C6-carbocyclic fused iminothiadiazine dioxides as BACE inhibitors, compositions, and their use |
Timothy A. Blizzard, Shawn P. Walsh, Jared N. Cumming |
2019-06-25 |
$97,538,000 |
| 10238743 |
C5-C6-fused tricyclic iminothiadiazine dioxide compounds as BACE inhibitors, compositions, and their use |
Shuwen He, Jared N. Cumming |
2019-03-26 |
$81,287,000 |
| 10227331 |
Metallo-β-lactamase inhibitors |
Frank Bennett, Jinlong Jiang, Alexander Pasternak, Shuzhi Dong, Xin Gu +12 more |
2019-03-12 |
$206,555,000 |
| 10221163 |
Metallo-beta-lactamase inhibitors |
Frank Bennett, Jinlong Jiang, Alexander Pasternak, Shuzhi Dong, Xin Gu +8 more |
2019-03-05 |
$69,271,000 |
| 10047098 |
C5-C6-oxacyclic fused iminopyrimidinone compounds as bace inhibitors, compositions, and their use |
Xing Dai, Jared N. Cumming, Hong Liu |
2018-08-14 |
$83,932,000 |
| 9957269 |
S-imino-S-oxo iminothiazine compounds as bace inhibitors, compositions, and their use |
Jared N. Cumming |
2018-05-01 |
$129,774,000 |
| 9802928 |
C-6 spirocarbocyclic iminothiadiazine dioxides as BACE inhibitors, compositions, and their use |
Jared N. Cumming, Timothy A. Blizzard, Michael Ellis |
2017-10-31 |
$123,750,000 |
| 9745324 |
Iminothiadiazepane dioxide compounds as BACE inhibitors, compositions, and their use |
Xing Dai, Jared N. Cumming, Hong Liu, Anandan Palani |
2017-08-29 |
$63,155,000 |
| 9725468 |
C5-spiro iminothiazine dioxides as BACE inhibitors, compositions, and their use |
Wen-Lian Wu, Jared N. Cumming |
2017-08-08 |
$65,756,000 |
| 9718818 |
Compounds inhibiting leucine-rich repeat kinase enzyme activity |
Duane DeMong, Thomas J. Greshock, Ronald K. Chang, Xing Dai, Hong Liu +4 more |
2017-08-01 |
$68,609,000 |
| 9688654 |
Compounds inhibiting leucine-rich repeat kinase enzyme activity |
Michael Miller, Kallol Basu, Duane DeMong, Hong Liu, Xing Dai +3 more |
2017-06-27 |
$105,730,000 |
| 9687494 |
Iminothiadiazine dioxide compounds as BACE inhibitors, compositions, and their use |
Andrew Stamford, Eric J. Gilbert, Jared N. Cumming, Ulrich Iserloh |
2017-06-27 |
$105,730,000 |
| 9580396 |
C6-spiro iminothiadiazine dioxides as BACE inhibitors, compositions, and their use |
Jared N. Cumming, Andrew Stamford, Ulrich Iserloh, Santhosh F. Neelamkavil, Pengcheng Patrick Shao +1 more |
2017-02-28 |
$88,591,000 |
| 9499502 |
5-substituted iminothiazines and their mono- and dioxides as BACE inhibitors, compositions, and their use |
Wen-Lian Wu, Duane A. Burnett, Andrew Stamford, Jared N. Cumming, Chad E. Bennett +3 more |
2016-11-22 |
$87,862,000 |
| 9493440 |
Compounds inhibiting leucine-rich repeat kinase enzyme activity |
Michael Miller, Kallol Basu, Duane DeMong, Wei Li, Andrew Stamford +2 more |
2016-11-15 |
$49,512,000 |
| 9489013 |
C6-azaspiro iminothiadiazine dioxides as bace inhibitors, compositions, and their use |
Jared N. Cumming, David E. Kaelin, Andrew Stamford, Ulrich Iserloh |
2016-11-08 |
$82,214,000 |
| 9475785 |
Iminothiadiazine dioxide compounds as BACE inhibitors, compositions and their use |
Andrew Stamford, Eric J. Gilbert, Jared N. Cumming, Ulrich Iserloh, Jeffrey A. Misiaszek +1 more |
2016-10-25 |
$117,189,000 |
| 9453034 |
C2-azaspiro iminothiazine dioxides as BACE inhibitors, compositions, and their use |
Eric J. Gilbert, Jared N. Cumming, Wen-Lian Wu, Duane A. Burnett, Andrew Stamford |
2016-09-27 |
$133,879,000 |
| 9447085 |
Iminothiadiazine dioxides containing a thioamide, amidine, or amide oxime group as BACE inhibitors, compositions, and their use |
Jared N. Cumming, Tesfaye Biftu |
2016-09-20 |
$78,200,000 |
| 9440952 |
Compounds inhibiting leucine-rich repeat kinase enzyme activity |
Michael Miller, Kallol Basu, Duane DeMong, Hong Liu, Xing Dai +9 more |
2016-09-13 |
$142,282,000 |
| 9428475 |
Iminothiadiazine dioxide compounds as BACE inhibitors, compositions, and their use |
Andrew Stamford, Eric J. Gilbert, Jared N. Cumming |
2016-08-30 |
$102,397,000 |
| 9428476 |
S-imino-S-oxo-iminothiadiazine compounds as BACE inhibitors, compositions, and their use |
Tanweer A. Khan, Jared N. Cumming |
2016-08-30 |
$102,397,000 |
