| 12378254 |
Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators |
Michael A. Letavic, Kiev S. Ly, Daniel J. Pippel, Dale A. Rudolph, Kathleen C. Sappey +6 more |
2025-08-05 |
|
| 11897900 |
Inhibitors of KEAP1-Nrf2 protein-protein interaction |
J. Kent Barbay, Gavin Hirst, Kevin D. Kreutter, David A. Kummer, Kelly J. McClure +5 more |
2024-02-13 |
$332,761,000 |
| 11827638 |
Imidazopyrrolopyridine as inhibitors of the JAK family of kinases |
Genesis M. Bacani, Tatiana Koudriakova, Paul J. Krawczuk, Kevin D. Kreutter, Kristi A. Leonard +6 more |
2023-11-28 |
$131,962,000 |
| 11667644 |
Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators |
Michael A. Letavic, Kiev S. Ly, Daniel J. Pippel, Dale A. Rudolph, Kathleen C. Sappey +6 more |
2023-06-06 |
$206,373,000 |
| 11427601 |
Inhibitors of KEAP1-Nrf2 protein-protein interaction |
J. Kent Barbay, Gavin Hirst, Kevin D. Kreutter, David A. Kummer, Kelly J. McClure +5 more |
2022-08-30 |
$641,310,000 |
| 11254673 |
Small molecule inhibitors of NF-κB inducing kinase |
J. Kent Barbay, Wendy Eccles, Michael D. Hack, Aaron T. Herrmann, William M. Jones +6 more |
2022-02-22 |
$192,742,000 |
| RE48841 |
Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators |
Michael A. Letavic, Kiev S. Ly, Daniel J. Pippel, Dale A. Rudolph, Kathleen C. Sappey +6 more |
2021-12-07 |
|
| 11059828 |
Disubstituted octahydropyrrolo[3,4-C]pyrroles as orexin receptor modulators |
Michael A. Letavic, Kiev S. Ly, Daniel J. Pippel, Dale A. Rudolph, Kathleen C. Sappey +6 more |
2021-07-13 |
$130,196,000 |
| 10981911 |
Imidazopyrrolopyridine as inhibitors of the JAK family of kinases |
Genesis M. Bacani, Tatiana Koudriakova, Paul J. Krawczuk, Kevin D. Kreutter, Kristi A. Leonard +6 more |
2021-04-20 |
$98,264,000 |
| 10947252 |
Inhibitors of KEAP1-Nrf2 protein-protein interaction |
J. Kent Barbay, Gavin Hirst, Kevin D. Kreutter, David A. Kummer, Kelly J. McClure +5 more |
2021-03-16 |
$128,294,000 |
| 10172856 |
2,4-diaminopyrimidine derivatives as histamine H4 modulators |
Genesis M. Bacani, James P. Edwards, Russell C. Smith, Mark S. Tichenor, Jennifer D. Venable +1 more |
2019-01-08 |
$79,972,000 |
| 9981909 |
Serotonin receptor modulators |
Nicholas I. Carruthers, Jill A. Jablonowski, Chandravadan R. Shah, Brock T. Shireman, Devin M. Swanson +2 more |
2018-05-29 |
$56,746,000 |
| 9695149 |
1,2,6-substituted benzimidazoles as flap modulators |
Curt A. Dvorak, Wendy Eccles, James P. Edwards, Steven Goldberg, Paul J. Krawczuk +7 more |
2017-07-04 |
|
| 9682971 |
1,2,5-Substituted benzimidazoles as flap modulators |
Charlotte Pooley Deckhut, Curt A. Dvorak, Wendy Eccles, James P. Edwards, Steven Goldberg +5 more |
2017-06-20 |
$117,780,000 |
| 9682972 |
1,2,5-substituted benzimidazoles as flap modulators |
Charlotte Pooley Deckhut, Curt A. Dvorak, Wendy Eccles, James P. Edwards, Steven Goldberg +5 more |
2017-06-20 |
$117,780,000 |
| 9265770 |
1,2,5-substituted benzimidazoles as FLAP modulators |
Charlotte Pooley Deckhut, Curt A. Dvorak, Wendy Eccles, James P. Edwards, Steven Goldberg +5 more |
2016-02-23 |
$58,494,000 |
| 9089569 |
1,2,6-substituted benzimidazoles as flap modulators |
Curt A. Dvorak, Wendy Eccles, James P. Edwards, Steven Goldberg, Paul J. Krawczuk +7 more |
2015-07-28 |
$45,878,000 |
| 9079911 |
Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators |
Michael A. Letavic, Kiev S. Ly, Daniel J. Pippel, Dale A. Rudolph, Kathleen C. Sappey +6 more |
2015-07-14 |
$42,716,000 |
| 9067917 |
1,2,5-substituted benzimidazoles as FLAP modulators |
Charlotte Pooley Deckhut, Curt A. Dvorak, Wendy Eccles, James P. Edwards, Steven Goldberg +5 more |
2015-06-30 |
$80,032,000 |
| 8952177 |
1,2,6-substituted benzimidazoles as FLAP modulators |
Curt A. Dvorak, Wendy Eccles, James P. Edwards, Steven Goldberg, Paul J. Krawczuk +7 more |
2015-02-10 |
$112,846,000 |
| 8653263 |
Disubstituted octahydropyrrolo[3,4-c]pyrroles as orexin receptor modulators |
Michael A. Letavic, Kiev S. Ly, Daniel J. Pippel, Dale A. Rudolph, Kathleen C. Sappey +6 more |
2014-02-18 |
$79,615,000 |
| 8642583 |
Serotonin receptor modulators |
Nicholas I. Carruthers, Jill A. Jablonowski, Chandravadan R. Shah, Brock T. Shireman, Devin M. Swanson +2 more |
2014-02-04 |
$69,352,000 |
| 8183239 |
Substituted piperazines and piperidines as modulators of the neuropeptide Y2 receptor |
Pascal Bonaventure, Nicholas I. Carruthers, Curt A. Dvorak, Jill A. Jablonowski, Dale A. Rudolph +4 more |
2012-05-22 |
$75,331,000 |
| 7897771 |
Fused heterocyclic compounds |
Nicholas I. Carruthers, Xiaohu Deng, Curt A. Dvorak, Annette Kwok, Jimmy T. Liang +3 more |
2011-03-01 |
$34,623,000 |
| 7402680 |
Fused heterocyclic compounds |
Nicholas I. Carruthers, Xiaohu Deng, Curt A. Dvorak, Annette Kwok, Jimmy T. Liang +3 more |
2008-07-22 |
$294,225,000 |
