| 11518771 |
Process for manufacturing alkyl 7-amino-5-methyl-[1,2,5]oxadiazolo[3,4-b]pyridine-carboxylate |
Juergen Daeubler, Michael Pangerl, Rolf Schmid, Sarah Unger |
2022-12-06 |
| 9187478 |
Substituted naphthyridines and their use as medicaments |
Matthias Hoffmann, Georg Dahmann, Dennis Fiegen, Sandra Handschuh, Jasna Klicic +6 more |
2015-11-17 |
| 8969568 |
Substituted naphthyridines and their use as medicaments |
Matthias Hoffmann, Georg Dahmann, Dennis Fiegen, Sandra Handschuh, Jasna Klicic +6 more |
2015-03-03 |
| 8933227 |
Selective synthesis of functionalized pyrimidines |
Gerd Kraemer, Sabrina Kusserow, Juergen Schnaubelt |
2015-01-13 |
| 8791260 |
Process for the preparation of acylguanidines and acylthioureas |
Joerg Kley, Daniel HAERLE, Sandra STEHLE |
2014-07-29 |
| 8729265 |
Regioselective preparation of 2-amino-5-trifluoromethylpyrimidine derivatives |
Gerd Kraemer |
2014-05-20 |
| 8664222 |
Specific salt, anhydrous and crystalline form of a dihydropteridione derivative |
Peter Sieger, Matthias Grauert, Rolf Schmid |
2014-03-04 |
| 8466318 |
Method of preparing chiral cyclic β-aminocarboxamides |
Gerd Kraemer, Zeno Andreas Leuter, Markus Ostermeier, Werner Rall, Claudia Ochs +1 more |
2013-06-18 |
| 8372974 |
Regioselective preparation of substituted pyrimidines |
Adil Duran, Gerd Kraemer |
2013-02-12 |
| 8329695 |
Crystalline form of the free base N-[trans-4-[4-(cyclopropylmethyl)-1-piperazinyl]cyclohexyl]-4-[[(7r)-7-ethyl-5,6,7,8-tetrahydro-5-methyl-8-(1-methylethyl)-6-oxo-2-pteridinyl]amino]-3-methoxy-benzamide |
Peter Sieger, Rolf Schmid, Stefan Goepper |
2012-12-11 |
| 8304541 |
Process for the manufacture of an indolinone derivative |
Joern Merten, Juergen Schnaubelt, Rolf Schmid, Werner Rall, Svenja Renner +2 more |
2012-11-06 |
| 8202867 |
Methods of using hydrates and polymorphs of 4-[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide |
Peter Sieger, Gerd Kraemer, Matthias Hoffmann |
2012-06-19 |
| 8188086 |
Specific salt, anhydrous and crystalline form of a dihydropteridione derivative |
Peter Sieger, Matthias Grauert, Rolf Schmid |
2012-05-29 |
| 8138341 |
Intermediate compounds useful for the manufacture of dihydropteridinones |
Gerd Kraemer, Ludwig Gutschera, Geert Asche |
2012-03-20 |
| 8138373 |
Process for the manufacture of dihydropteridinones |
Gerd Kraemer, Ludwig Gutschera, Geert Asche |
2012-03-20 |
| RE43115 |
Process for the manufacture of fused piperazin-2-one derivatives |
Adil Duran |
2012-01-17 |
| 8034816 |
Hydrates and polymorphs of 4-[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament |
Peter Sieger, Gerd Kraemer, Rolf Herter, Matthias Hoffmann, Werner Rall +1 more |
2011-10-11 |
| 7759485 |
Process for the manufacture of dihydropteridinones |
Gerd Kraemer, Ludwig Gutschera, Geert Asche |
2010-07-20 |
| 7728134 |
Hydrates and polymorphs of 4[[(7R)-8-cyclopentyl-7-ethyl-5,6,7,8-tetrahydro-5-methyl-6-oxo-2-pteridinyl]amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide, process for their manufacture and their use as medicament |
Peter Sieger, Gerd Kraemer, Rolf Herter, Matthias Hoffmann, Werner Rall +1 more |
2010-06-01 |
| 7626019 |
Intermediate compounds for the manufacture of fused piperazin-2-one derivatives |
Adil Duran |
2009-12-01 |
| 7514468 |
Indolinone derivatives substituted in the 6 position, the preparation thereof and their use as pharmaceutical compositions |
Armin Heckel, Frank Hilberg, Thorsten Lehmann-Lintz, Joerg Kley, Jacobus Van Meel +4 more |
2009-04-07 |
| 7439358 |
Specific salt, anhydrous and crystalline form of a dihydropteridione derivative |
Peter Sieger, Matthias Grauert, Rolf Schmid |
2008-10-21 |
| 7294721 |
(R)-2-(4-amidinophenylaminomethyl)-1-methyl-5-[1-(carboxymethylamino)-1(pyrrolidinocarbonyl)-ethyl]-benzimidazole, the monohydrochloride thereof, preparation thereof and the use as pharmaceutical composition |
Peter Sieger, Gunnar Schreiner, Werner Rall, Rolf Schmid |
2007-11-13 |
| 7238807 |
Process for the manufacture of fused piperazin-2-one derivatives |
Adil Duran |
2007-07-03 |
| 7169934 |
(R) 2-(4-amidinophenylaminomethyl)-1-methyl-5-[1-(carboxymethylamino)-1 (pyrrolidinocarbonyl)-ethyl]-benzimidazole, the monohydrochloride thereof, preparation thereof and the use as pharmaceutical composition |
Peter Sieger, Gunnar Schreiner, Werner Rall, Rolf Schmid |
2007-01-30 |