| 12351571 |
Substituted quinoxaline compounds as inhibitors of FGFR tyrosine kinases |
James F. Blake, Li Ren, Shane M. Walls |
2025-07-08 |
|
| 12303509 |
Compounds for the treatment of BRAF-associated diseases and disorders |
Patrick Michael DOERNER BARBOUR, Tanna Bettendorf, Dean Russell Kahn, Alex Andrew KELLUM, Ellen Laird +1 more |
2025-05-20 |
|
| 12180207 |
Substituted pyrazolo[1,5-a]pyridine compounds as inhibitors of FGFR tyrosine kinases |
James F. Blake, Li Ren, Tony P. Tang, Shane M. Walls |
2024-12-31 |
|
| 11998545 |
Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors |
Steven W. Andrews, Sean Aronow, James F. Blake, Barbara J. Brandhuber, Adam Cook +9 more |
2024-06-04 |
|
| 11964988 |
Fused heterocyclic compounds as RET kinase inhibitors |
James F. Blake, Donghua Dai, Julia Haas, Yutong Jiang, Dean Russell Kahn +9 more |
2024-04-23 |
|
| 11851434 |
Substituted pyrazolo[1,5-A]pyrazine compounds as ret kinase inhibitors |
Steven W. Andrews, James F. Blake, Julia Haas, Yutong Jiang, Gabrielle R. Kolakowski +2 more |
2023-12-26 |
|
| 11807651 |
Process for the preparation of 6-(2-hydroxy-2-methylpropoxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile |
Charles Todd Eary, Stacey Spencer, Zack Crane, Katelyn Chando, Sylvie M. Asselin +6 more |
2023-11-07 |
|
| 11802127 |
3,4-dihydro-2,7-naphthyridine-1,6(2H,7H)-diones as MEK inhibitors |
Shelley Allen, Patrick Michael DOERNER BARBOUR, James F. Blake, Mark Laurence Boys, Joshua Ryan Dahlke +3 more |
2023-10-31 |
$284,263,000 |
| 11691973 |
3,4-dihydro-2,7-naphthyridine-1,6(2H,7H)-diones as MEK inhibitors |
Shelley Allen, Patrick Michael DOERNER BARBOUR, James F. Blake, Sydney Taylor BLANCHE, Mark Laurence Boys +9 more |
2023-07-04 |
|
| 11648243 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors |
Steven W. Andrews, Sean Aronow, James F. Blake, Barbara J. Brandhuber, James Collier +12 more |
2023-05-16 |
|
| 11634409 |
Compounds for the treatment of BRAF-associated diseases and disorders |
Patrick Barbour, Katie Keaton BROWN, Adam Cook, Erik James Hicken, Dean Russell Kahn +7 more |
2023-04-25 |
|
| 11603374 |
Substituted pyrrolo[2,3-d]pyrimidines compounds as ret kinase inhibitors |
James F. Blake, Donghua Dai, Julia Haas, Yutong Jiang, Gabrielle R. Kolakowski +6 more |
2023-03-14 |
|
| 11524963 |
Substituted pyrazolo[3,4-d]pyrimidines as RET kinase inhibitors |
James F. Blake, Donghua Dai, Julia Haas, Yutong Jiang, Gabrielle R. Kolakowski +3 more |
2022-12-13 |
|
| 11472802 |
Substituted pyrazolyl[4,3-c]pyridine compounds as RET kinase inhibitors |
Shane M. Walls, Li Ren, Ginelle A. Ramann, Andrew T. Metcalf, Elizabeth A. McFaddin +6 more |
2022-10-18 |
|
| 11414404 |
Compounds for the treatment of BRAF-associated diseases and disorders |
Patrick Barbour, Katie Keaton BROWN, Adam Cook, Erik James Hicken, Dean Russell Kahn +7 more |
2022-08-16 |
|
| 11168090 |
Substituted pyrazolo[1,5-a]pyrazines as RET kinase inhibitors |
Steven W. Andrews, James F. Blake, Julia Haas, Yutong Jiang, Gabrielle R. Kolakowski +2 more |
2021-11-09 |
|
| 11098064 |
Process for the preparation of 6-(2-hydroxy-2-methylpropoxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carbontrile |
Charles Todd Eary, Stacey Spencer, Zack Crane, Katelyn Chando, Sylvie M. Asselin +6 more |
2021-08-24 |
|
| 10953005 |
Substituted pyrazolo[1,5-a]pyridine compounds as RET kinase inhibitors |
Steven W. Andrews, Sean Aronow, James F. Blake, Barbara J. Brandhuber, Adam Cook +9 more |
2021-03-23 |
|
| 10881652 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors |
Steven W. Andrews, Sean Aronow, James F. Blake, Barbara J. Brandhuber, James Collier +12 more |
2021-01-05 |
|
| 10766881 |
2-aryl- and 2-heteroaryl-substituted 2-pyridazin-3(2H)-one compounds as inhibitors of FGFR tyrosine kinases |
Steven W. Andrews, James F. Blake, Adam Cook, Indrani W. Gunawardana, Kevin W. Hunt +3 more |
2020-09-08 |
|
| 10745419 |
Process for the preparation of 6-(2-hydroxy-2-methylpropoxy)-4-(6-(6-((6-methoxypyridin-3-yl)methyl)-3,6-diazabicyclo[3.1.1]heptan-3-yl)pyridin-3-yl)pyrazolo[1,5-a]pyridine-3-carbonitrile |
Charles Todd Eary, Stacey Spencer, Zack Crane, Katelyn Chando, Sylvie M. Asselin +6 more |
2020-08-18 |
|
| 10555944 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors |
Steven W. Andrews, Sean Aronow, James F. Blake, Barbara J. Brandhuber, Adam Cook +9 more |
2020-02-11 |
$289,171,000 |
| 10519126 |
Serine/threonine kinase inhibitors |
James F. Blake, Mark Joseph Chicarelli, Rustam Ferdinand Garrey, John Gaudino, Jonas Grina +6 more |
2019-12-31 |
|
| 10441581 |
Substituted pyrazolo[1,5-A]pyridine compounds as RET kinase inhibitors |
Steven W. Andrews, Sean Aronow, James F. Blake, Barbara J. Brandhuber, James Collier +12 more |
2019-10-15 |
|
| 10208024 |
2-aryl- and 2-heteroaryl-substituted 2-pyridazin-3(2H)-one compounds as inhibitors of FGFR tyrosine kinases |
Steven W. Andrews, James F. Blake, Adam Cook, Indrani W. Gunawardana, Kevin W. Hunt +3 more |
2019-02-19 |
$53,065,000 |
