| 12428425 |
Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use |
Lara C. Czabaniuk, Timothy Hopper, Jonathan Houze, Jane Panteleev, Gwenaella Rescourio +7 more |
2025-09-30 |
|
| 12319691 |
Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use |
Lara C. Czabaniuk, Timothy Hopper, Jonathan Houze, Gwenaella Rescourio, Vincent Santora +3 more |
2025-06-03 |
|
| 12252489 |
Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use |
Lara C. Czabaniuk, Timothy Hopper, Jonathan Houze, Gwenaella Rescourio, Vincent Santora +3 more |
2025-03-18 |
|
| 11912711 |
Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use |
Lara C. Czabaniuk, Timothy Hopper, Jonathan Houze, Jane Panteleev, Gwenaella Rescourio +7 more |
2024-02-27 |
$716,893,000 |
| 11884675 |
Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use |
Lara C. Czabaniuk, Timothy Hopper, Jonathan Houze, Jane Panteleev, Gwenaella Rescourio +7 more |
2024-01-30 |
$465,532,000 |
| 11718617 |
Heterocyclic compounds as triggering receptor expressed on myeloid cells2 agonists and methods of use |
Lara C. Czabaniuk, Timothy Hopper, Jonathan Houze, Gwenaella Rescourio, Vincent Santora +3 more |
2023-08-08 |
$855,538,000 |
| 11608344 |
Heterocyclic compounds as triggering receptor expressed on myeloid cells 2 agonists and methods of use |
Lara C. Czabaniuk, Timothy Hopper, Jonathan Houze, Jane Panteleev, Gwenaella Rescourio +7 more |
2023-03-21 |
$375,298,000 |
| 11572374 |
N-cyano-7-azanorbornane derivatives and uses thereof |
John R. BUTLER, Daniel Erlanson, Russell Graceffa, Jeffrey Iwig, Joon Won Jeong +5 more |
2023-02-07 |
$408,490,000 |
| 11332459 |
Benzimidazole derivatives and their uses |
Michael D. Bartberger, Nagasree Chakka, Hua Gao, Angel Guzman-Perez, Daniel B. Horne +9 more |
2022-05-17 |
|
| 9777019 |
Amino-oxazine and amino-dihydrothiazine compounds as beta-secretase modulators and methods of use |
Yuan Cheng, Ana Elena Minatti, Bryant Yang, Xiao Mei Zheng, Patricia Lopez +5 more |
2017-10-03 |
$315,293,000 |
| 9725469 |
Amino-oxazine and amino-dihydrothiazine compounds as beta-secretase modulators and methods of use |
Oleg Epstein, Jason Brooks Human, Xiao Mei Zheng, Yuan Cheng, Kelvin Sham +2 more |
2017-08-08 |
$588,174,000 |
| 9611261 |
Perfluorinated cyclopropyl fused 1,3-oxazin-2-amine compounds as beta-secretase inhibitors and methods of use |
Ana Elena Minatti, Jonathan D. Low, Jennifer R. Allen, Albert Amegadzie, James Brown +12 more |
2017-04-04 |
$276,197,000 |
| 9556135 |
Amino-dihydrothiazine and amino-dioxido dihydrothiazine compounds as beta-secretase antagonists and methods of use |
Richard T. Lewis, Jennifer R. Allen, Yuan Cheng, Deborah Choquette, Oleg Epstein +18 more |
2017-01-31 |
$569,268,000 |
| 9550762 |
Cyclopropyl fused thiazin-2-amine compounds as beta-secretase inhibitors and methods of use |
Jennifer R. Allen, Albert Amegadzie, Matthew P. Bourbeau, James Brown, Jian Chen +21 more |
2017-01-24 |
$492,282,000 |
| 9365522 |
Pyrazole amide derivative |
Hilary Plake Beck, Shon Booker, Howard Bregman, Victor J. Cee, Nagasree Chakka +22 more |
2016-06-14 |
$275,500,000 |
| 9346827 |
5-amino-oxazepine and 5-amino-thiazepane compounds as beta secretase antagonists and methods of use |
Thomas A. Dineen, Matthew Weiss, Vinod F. Patel, Xiao Mei Zheng |
2016-05-24 |
$192,745,000 |
| 9309263 |
Fused multi-cyclic sulfone compounds as inhibitors of beta-secretase and methods of use thereof |
Jennifer R. Allen, Oleg Epstein, Fang-Tsao Hong, Zihao Hua, Jason Brooks Human +7 more |
2016-04-12 |
$193,659,000 |
| 9296759 |
Amino-oxazine and amino-dihydrothiazine compounds as beta-secretase modulators and methods of use |
Yuan Cheng, Ana Elena Minatti, Bryant Yang, Xiao Mei Zheng, Patricia Lopez +5 more |
2016-03-29 |
$89,902,000 |
| 9096615 |
Bridged bicyclic amino thiazine dioxide compounds as inhibitors of beta-secretase and methods of use thereof |
Richard T. Lewis, Jennifer R. Allen, James Brown, Angel Guzman-Perez, Zihao Hua +6 more |
2015-08-04 |
$114,332,000 |
| 9085576 |
Perfluorinated cyclopropyl fused 1,3-oxazin-2-amine compounds as beta-secretase inhibitors and methods of use |
Ana Elena Minatti, Jonathan D. Low, Jennifer R. Allen, Albert Amegadzie, James Brown +12 more |
2015-07-21 |
$288,742,000 |
| 9012446 |
Amino-oxazines and amino-dihydrothiazine compounds as beta-secretase modulators and methods of use |
Jian Chen, Wenge Zhong, Patricia Lopez, Matthew Weiss, Ted Judd +6 more |
2015-04-21 |
$150,202,000 |
| 8962859 |
Spiro-amino-imidazo-fused heterocyclic compounds as beta-secretase modulators and methods of use |
Oleg Epstein, Vinod F. Patel, Jason Brooks Human |
2015-02-24 |
$566,405,000 |
| 8957083 |
Spiro-amino-imidazolone and spiro-amino-dihydro-pyrimidinone compounds as beta-secretase modulators and methods of use |
Ana Elena Minatti, Oleg Epstein, Matthew Weiss, Wenge Zhong, Jonathan D. Low |
2015-02-17 |
$285,124,000 |
| 8883782 |
Spiro-tetracyclic ring compounds as beta-secretase modulators and methods of use |
Yuan Cheng, Albert Amegadzie, James Brown, Alan C. Cheng, Erin F. Dimauro +19 more |
2014-11-11 |
$176,830,000 |
| 8557816 |
Aurora kinase modulators and method of use |
Stephanie Geuns-Meyer, Victor J. Cee, Isaac Marx, Laurie B. Schenkel |
2013-10-15 |
$167,714,000 |