| 12486280 |
CDK inhibitors and uses thereof |
Brendan M. O'Boyle, Justin A. Hilf, Scott C. Virgil, Alexander W. Sun, Bruce Stoltz +5 more |
2025-12-02 |
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| 12466842 |
Substituted pyrido [4,3-d]pyrimidines as KRAS modulators |
Yi Fan, Eric A. Murphy, Xuefeng Zhu |
2025-11-11 |
|
| 12428416 |
ERK inhibitors and uses thereof |
Corey REEVES, Brendan M. O'Boyle, Justin A. Hilf, Dylan Conklin, Martina S. McDermott +6 more |
2025-09-30 |
|
| 12209087 |
AKT1 modulators |
Elena Dneprovskaia, Yi Fan, Eric A. Murphy, Xuefeng Zhu |
2025-01-28 |
|
| 11999730 |
AKT1 modulators |
Elena Dneprovskaia, Yi Fan, Eric A. Murphy, Xuefeng Zhu |
2024-06-04 |
|
| 11407721 |
CIS-morpholinone and other compounds as MDM2 inhibitors for the treatment of cancer |
Hilary Plake Beck, Michael R. DeGraffenreid, Brian M. Fox, Felix Gonzalez Lopez De Turiso, Lisa Julian +7 more |
2022-08-09 |
$237,532,000 |
| 11332459 |
Benzimidazole derivatives and their uses |
Nagasree Chakka, Hua Gao, Angel Guzman-Perez, Daniel B. Horne, Zihao Hua +9 more |
2022-05-17 |
|
| 11096939 |
KRAS G12C inhibitors and methods of using the same |
Shon Booker, John Gordon Allen, Brian Alan LANMAN, Ryan Wurz, Ning Chen +3 more |
2021-08-24 |
$214,522,000 |
| 11045484 |
KRAS G12C inhibitors and methods of using the same |
Ryan Wurz, Victor J. Cee, Albert Amegadzie, Ning Chen, Brian Alan LANMAN |
2021-06-29 |
$263,699,000 |
| 10988485 |
KRAS G12C inhibitors and methods of using the same |
Ana Elena Minatti, Jonathan D. Low, Ryan Wurz, Brian Alan LANMAN, Victor J. Cee +1 more |
2021-04-27 |
$240,492,000 |
| 9593129 |
Piperidinone derivatives as MDM2 inhibitors for the treatment of cancer |
Ana Z. Gonzalez Buenrostro, Hilary Plake Beck, Xiaoqi Chen, Richard V. Connors, Jeffrey Deignan +36 more |
2017-03-14 |
$585,925,000 |
| 9376425 |
Heterocyclic compounds as MDM2 inhibitors for the treatment of cancer |
Hilary Plake Beck, Xiaoqi Chen, Richard V. Connors, Jeffrey Deignan, Jason A. Duquette +25 more |
2016-06-28 |
$131,915,000 |
| 9296736 |
Piperidinone derivatives as MDM2 inhibitors for the treatment of cancer |
Ana Z. Gonzalez Buenrostro, Hilary Plake Beck, Xiaoqi Chen, Richard V. Connors, Jeffrey Deignan +36 more |
2016-03-29 |
$89,902,000 |
| 8686011 |
Inhibitors of 11-β-hydroxy steroid dehydrogenase type 1 |
Martin Henriksson, Evert Homan, Lars Johansson, Jerk Vallgarda, Meredith Williams +13 more |
2014-04-01 |
$134,432,000 |
| 8541592 |
Inhibitors of 11-beta-hydroxysteroid dehydrogenase type 1 |
Martin Henriksson, Evert Homan, Lars Johansson, Jerk Vallgarda, Meredith Williams +14 more |
2013-09-24 |
$116,900,000 |
| 8431563 |
Compounds that interact with glucokinase regulatory protein for the treatment of diabetes |
Kate Ashton, Yunxin Y. Bo, Marian C. Bryan, Michael Croghan, Christopher H. Fotsch +12 more |
2013-04-30 |
$350,213,000 |
| 8163766 |
Beta-secretase modulators and methods of use |
Wenge Zhong, Stephen Hitchcock, Vinod F. Patel, Yuan Cheng, Michael Croghan +21 more |
2012-04-24 |
$50,592,000 |
| 7973047 |
Beta-Secretase modulators and methods of use |
Wenge Zhong, Stephen Hitchcock, Brian K. Albrecht, James Brown, Ryan Brown +22 more |
2011-07-05 |
$54,551,000 |
| 7872009 |
Beta-Secretase modulators and methods of use |
Brian K. Albrecht, Denise Andersen, James Brown, Ryan Brown, Stuart C. Chaffee +21 more |
2011-01-18 |
$66,764,000 |
| 7838676 |
Beta-secretase modulators and methods of use |
Qiufen Xue, Brian K. Albrecht, Denise Andersen, James Brown, Ryan Brown +21 more |
2010-11-23 |
$222,385,000 |
| 7807700 |
Inhibitors of 11-β-hydroxy steroid dehydrogenase type 1 |
Martin Henriksson, Evert Homan, Lars Johansson, Jerk Vallgarda, Meredith Williams +13 more |
2010-10-05 |
$125,969,000 |
| 7745484 |
Beta-secretase modulators and methods of use |
Wenge Zhong, Stephen Hitchcock, Brian K. Albrecht, James Brown, Ryan Brown +22 more |
2010-06-29 |
$108,739,000 |
| 7666888 |
Substituted azole aromatic heterocycles as inhibitors of 11β-HSD-1 |
Christopher H. Fotsch, Martin Haraldsson, David J. St. Jean, Jr., Lars Johansson, Marianne Nilsson +2 more |
2010-02-23 |
$84,573,000 |
| 7253196 |
Inhibitors of 11-β-hydroxy steroid dehydrogenase type 1 |
Martin Henriksson, Evert Homan, Lars Johansson, Jerk Vallgarda, Meredith Williams +13 more |
2007-08-07 |
$136,283,000 |
