| 10385337 |
Oligonucleotide end caps |
Kallanthottathil G. Rajeev |
2019-08-20 |
| 10369226 |
Biodegradable lipids for the delivery of active agents |
Martin Maier, Muthusamy Jayaraman, Akin Akinc, Shigeo Matsuda, Pachamuthu Kandasamy +1 more |
2019-08-06 |
| 10273477 |
Therapeutic compositions |
Kallanthottathil G. Rajeev, David Bumcrot |
2019-04-30 |
| 10266484 |
Biodegradable lipids for the delivery of active agents |
Martin Maier, Muthusamy Jayaraman, Shigeo Matsuda, Jayaprakash K. Nair, Kallanthottathil G. Rajeev +2 more |
2019-04-23 |
| 10266825 |
Compositions comprising alternating 2′-modified nucleosides for use in gene modulation |
Charles Allerson, Balkrishen Bhat, Anne B. Eldrup, Richard H. Griffey, Brenda F. Baker +1 more |
2019-04-23 |
| 10233448 |
Modified double-stranded RNA agents |
Martin Maier, Don Foster, Stuart Milstein, Satya Kuchimanchi, Vasant Jadhav +2 more |
2019-03-19 |
| 10131908 |
5′ phosphate mimics |
Kallanthottathil G. Rajeev, Marija Prhavc, Ivan Zlatev |
2018-11-20 |
| 10125369 |
PCSK9 iRNA compositions and methods of use thereof |
Anna Borodovsky, Kallanthottathil G. Rajeev, Kevin Fitzgerald, Maria Frank-Kamenetsky, William Querbes +4 more |
2018-11-13 |
| 10119138 |
iRNA agents with biocleavable tethers |
Kallanthottathil G. Rajeev |
2018-11-06 |
| 10119136 |
RNAi agents modified at the 4′-C position |
Shigeo Matsuda, Kallanthottathil G. Rajeev, Ivan Zlatev |
2018-11-06 |
| 10117941 |
Lipids and compositions for the delivery of therapeutics |
Kallanthottathil G. Rajeev, Muthusamy Jayaraman, David Butler, Jayaprakash K. Nair, Martin Maier +1 more |
2018-11-06 |
| 10086081 |
Carbohydrate conjugated RNA agents and process for their preparation |
Jayaprakash K. Nair, Alexander V. Kelin, Pachamuthu Kandasamy, Kallanthottathil G. Rajeev |
2018-10-02 |
| 10030244 |
Serpina1 iRNA compositions and methods of use thereof |
Alfica Sehgal, Klaus Charisse, Brian Bettencourt, Martin Maier, Kallanthottathil G. Rajeev +1 more |
2018-07-24 |
| 9999673 |
PEGylated lipids and their use for drug delivery |
Kallanthottathil G. Rajeev, Muthusamy Jayaraman, Martin Maier, Jayaprakash K. Nair, David Butler |
2018-06-19 |
| 9970006 |
Compositions and methods for inhibition of expression of apolipoprotein C-III (APOC3) genes |
Brian Bettencourt, Kevin Fitzgerald, Stuart Milstein, Martin Maier, Klaus Charisse +3 more |
2018-05-15 |
| 9895448 |
Site-specific delivery of nucleic acids by combining targeting ligands with endosomolytic components |
Kallanthottathil G. Rajeev, David Butler, Muthusamy Jayaraman |
2018-02-20 |
| 9867882 |
Carbohydrate conjugates as delivery agents for oligonucleotides |
Kallanthottathil G. Rajeev, Jayaprakash K. Nair, Martin Maier |
2018-01-16 |
| 9850488 |
Complement component C5 iRNA compositions and methods of use thereof |
Kevin Fitzgerald, James Butler, Brian Bettencourt, Anna Borodovsky, Satyanarayana Kuchimanchi +4 more |
2017-12-26 |
| 9814777 |
Targeting lipids |
Kallanthottathil G. Rajeev, Jayaprakash K. Nair, Muthusamy Jayaraman |
2017-11-14 |
| 9796974 |
Modified RNAi agents |
Kallanthottathil G. Rajeev, Tracy Zimmermann, Martin Maier, Satyanarayana Kuchimanchi, Klaus Charisse |
2017-10-24 |
| 9771578 |
Phosphorous-linked oligomeric compounds and their use in gene modulation |
Brenda F. Baker, Anne B. Eldrup, Balkrishen Bhat, Richard H. Griffey, Eric E. Swayze +1 more |
2017-09-26 |
| 9764036 |
Lipids and compositions for the delivery of therapeutics |
Kallanthottathil G. Rajeev, David Butler, Jayaprakash K. Nair, Muthusamy Jayaraman, Laxman Eltepu |
2017-09-19 |
| 9725479 |
5′-end derivatives |
Kallanthottathil G. Rajeev, Ivan Zlatev, Eric E. Swayze, Thazha P. Prakash, Walter F. Lima |
2017-08-08 |
| 9708615 |
Therapeutic compositions |
Kallanthottathil G. Rajeev, David Bumcrot |
2017-07-18 |
| 9708610 |
Compositions comprising alternating 2′-modified nucleosides for use in gene modulation |
Charles Allerson, Balkrishen Bhat, Ann B. Eldrup, Richard H. Griffey, Brenda F. Baker +1 more |
2017-07-18 |