Issued Patents All Time
Showing 1–24 of 24 patents
| Patent # | Title | Co-Inventors | Date |
|---|---|---|---|
| 11369606 | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use | Brian D. KLEIN, Hilde Lavreysen, Stefan Maria Christiaan Pype, Roy E. Twyman, Nancy Eulalie Sylvain Van Osselaer +4 more | 2022-06-28 |
| 10537573 | Combinations comprising positive allosteric modulators or orthosteric agonists of metabotropic glutamatergic receptor subtype 2 and their use | Brian D. KLEIN, Hilde Lavreysen, Stefan Maria Christiaan Pype, Roy E. Twyman, Nancy Eulalie Sylvain Van Osselaer +4 more | 2020-01-21 |
| 8883473 | Methods of treatment using allosteric processing inhibitors for matrix metalloproteinases | Kristi A. Leonard, Richard S. Alexander, Joseph Kent Barbay, Carl Crysler, Ingrid Deckman +15 more | 2014-11-11 |
| 8798939 | Methods for designing, selecting and/or optimizing allosteric processing inhibitors for matrix metalloproteinases | Kristi A. Leonard, Richard S. Alexander, Joseph Kent Barbay, Ingrid Deckman, Paul F. Jackson +12 more | 2014-08-05 |
| 8753857 | Crystal structure of the pro form of a matrix metalloproteinase and an allosteric processing inhibitor | Kristi A. Leonard, Richard S. Alexander, Joseph Kent Barbay, Ingrid Deckman, Paul F. Jackson +12 more | 2014-06-17 |
| 7482376 | Conjugated complement cascade inhibitors | Nalin Subasinghe, Ehab M. Khalil, Farah Ali, Heather Rae Hufnagel, Shelley K. Ballentine +2 more | 2009-01-27 |
| 7030110 | Cyclic oxyguanidine pyrazinones as protease inhibitors | Aihua Wang, Bruce E. Tomczuk, Tianbao Lu, Richard Soll, John Spurlino | 2006-04-18 |
| 6849458 | Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimization | Michael W. Pantoliano, Alexander W. Rhind, Francis R. Salemme | 2005-02-01 |
| 6635637 | Cyclic oxyguanidine protease inhibitors | Aihua Wang, Tianbao Lu, Bruce E. Tomczuk, Richard Soll, John Spurlino | 2003-10-21 |
| 6515002 | Compounds and compositions for treating C1s-mediated diseases and conditions | Carl R. Illig, Nalin Subasinghe, James B. Hoffman, Kenneth Wilson, M. Jonathan Rudolph +2 more | 2003-02-04 |
| 6492403 | Methods of treating C1s-mediated diseases and conditions and compositions thereof | Carl R. Illig, Nalin Subasinghe, James B. Hoffman, Kenneth Wilson, M. Jonathan Rudolph +2 more | 2002-12-10 |
| 6476016 | Cyclic oxyguanidine pyrazinones as protease inhibitors | Aihua Wang, Bruce E. Tomczuk, Tianbao Lu, Richard Soll, John Spurlino | 2002-11-05 |
| 6434490 | Method of generating chemical compounds having desired properties | Dimitris Agrafiotis, Francis R. Salemme, Richard Soll | 2002-08-13 |
| 6421612 | System, method and computer program product for identifying chemical compounds having desired properties | Dimitris Agrafiotis, Francis R. Salemme, Richard Soll | 2002-07-16 |
| 6326492 | Heterocyclic protease inhibitors | Aihua Wang, Tianbao Lu, Bruce E. Tomczuk, Richard Soll, John Spurlino | 2001-12-04 |
| 6268218 | Method for sensing and processing fluorescence data from multiple samples | Michael W. Pantoliano, Alexander W. Rhind, Francis R. Salemme | 2001-07-31 |
| 6214293 | Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimization | Michael W. Pantoliano, Alexander W. Rhind, Francis R. Salemme | 2001-04-10 |
| 6036920 | Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimization | Michael W. Pantoliano, Alexander W. Rhind, Francis R. Salemme | 2000-03-14 |
| 5901069 | System, method, and computer program product for at least partially automatically generating chemical compounds with desired properties from a list of potential chemical compounds to synthesize | Dimitris Agrafiotis, Francis R. Salemme, Richard Soll | 1999-05-04 |
| 5792769 | Guanidino protease inhibitors | Tianbao Lu, Carl R. Illig, Bruce E. Tomczuk, Richard Soll, Nalin Subasinghe | 1998-08-11 |
| 5684711 | System, method, and computer program for at least partially automatically generating chemical compounds having desired properties | Dimitris Agrafiotis, Francis R. Salemme, Richard Soll | 1997-11-04 |
| 5612369 | Thrombin inhibitors | Richard Soll, Carl L. Illig, Tianbao Lu, Nalin Subasinghe | 1997-03-18 |
| 5574656 | System and method of automatically generating chemical compounds with desired properties | Dimitris Agrafiotis, Francis R. Salemme, Richard Soll | 1996-11-12 |
| 5463564 | System and method of automatically generating chemical compounds with desired properties | Dimitris Agrafiotis, Francis R. Salemme, Richard Soll | 1995-10-31 |