Issued Patents All Time
Showing 1–24 of 24 patents
| Patent # | Title | Co-Inventors | Date |
|---|---|---|---|
| 7138374 | Methods of using analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamate 89, asparate 101 or leucine 137 | Barry A. Springer, Celia M. Sharp | 2006-11-21 |
| 7122321 | High throughput method for functionally classifying proteins identified using a genomics approach | Francis R. Salemme, Theodore Carver | 2006-10-17 |
| 6849458 | Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimization | Roger F. Bone, Alexander W. Rhind, Francis R. Salemme | 2005-02-01 |
| 6767722 | Analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamate 89, Aspartate 101 or Leucine 137 | Barry A. Springer, Celia M. Sharp | 2004-07-27 |
| 6737404 | Methods of using analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamate 89, aspartate 101 or leucine 137 | Barry A. Springer, Celia M. Sharp | 2004-05-18 |
| 6569631 | Microplate thermal shift assay for ligand development using 5-(4″dimethylaminophenyl)-2-(4′-phenyl)oxazole derivative fluorescent dyes | Eugenio C. Petrella, F. Raymond Salemme, Barry A. Springer | 2003-05-27 |
| 6303322 | Method for identifying lead compounds | Alexander W. Rhind, Francis R. Salemme | 2001-10-16 |
| 6291192 | Method for identifying conditions that facilitate recombinant protein folding | Eugenio C. Petrella, Francis R. Salemme, Barry A. Springer | 2001-09-18 |
| 6291191 | Microplate thermal shift assay for ligand development and multi-variable protein chemistry optimization | Eugenio C. Petrella, Alexander W. Rhind, Francis R. Salemme, Barry A. Springer | 2001-09-18 |
| 6274712 | Analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamute 89, aspartate 101 or leucine 137 | Barry A. Springer, Celia M. Sharp | 2001-08-14 |
| 6268218 | Method for sensing and processing fluorescence data from multiple samples | Roger F. Bone, Alexander W. Rhind, Francis R. Salemme | 2001-07-31 |
| 6268158 | Method for determining conditions that facilitate protein crystallization | Eugenio C. Petrella, Francis R. Salemme, Barry A. Springer | 2001-07-31 |
| 6232085 | Method for determining conditions that stabilize proteins | Eugenio C. Petrella, Francis R. Salemme, Barry A. Springer | 2001-05-15 |
| 6214293 | Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimization | Roger F. Bone, Alexander W. Rhind, Francis R. Salemme | 2001-04-10 |
| 6036920 | Microplate thermal shift assay apparatus for ligand development and multi-variable protein chemistry optimization | Roger F. Bone, Alexander W. Rhind, Francis R. Salemme | 2000-03-14 |
| 6020141 | Microplate thermal shift assay for ligand development and multi-variable protein chemistry optimization | Alexander W. Rhind, Francis R. Salemme | 2000-02-01 |
| 5260207 | Engineering of electrostatic interactions at metal ion binding sites for the stabilization of proteins | Barry Finzel, Philip Bryan | 1993-11-09 |
| 5246849 | Thermally stable serine proteases | Philip Bryan | 1993-09-21 |
| 5116741 | Biosynthetic uses of thermostable proteases | Philip Bryan, Michele Rollence, Chi-Huey Wong | 1992-05-26 |
| 5013657 | Subtilisin mutations | Philip Bryan | 1991-05-07 |
| 4990452 | Combining mutations for stabilization of subtilisin | Philip Bryan | 1991-02-05 |
| 4980288 | Subtilisin with increased thermal stability | Philip Bryan, Michele Rollence | 1990-12-25 |
| 4908773 | Computer designed stabilized proteins and method for producing same | Robert Charles Ladner | 1990-03-13 |
| 4853871 | Computer-based method for designing stablized proteins | Robert Charles Ladner | 1989-08-01 |