| 12285427 |
Treatment of a senescence-associated ocular disease or disorder using a Bcl-xL selective inhibitor |
Remi-Martin Laberge, Judith Campisi, Marco Demaria, Bennett G. Childs, Jan M.A. van Deursen +1 more |
2025-04-29 |
|
| 11980616 |
Treating liver disease by selectively eliminating senescent cells |
Remi-Martin Laberge, Judith Campisi, Marco Demaria, James L. Kirkland, Tamar Tchkonia +1 more |
2024-05-14 |
|
| 11963957 |
Treating cardiovascular disease by selectively eliminating senescent cells |
Remi-Martin Laberge, Judith Campisi, Albert Davalos, Marco Demaria, Jan M.A. van Deursen +2 more |
2024-04-23 |
|
| 11865123 |
Methods of inhibiting pathological angiogenesis |
Pam Tsuruda, Jill Hopkins, Harry Sweigard, Yan Poon, Jamie Dananberg +1 more |
2024-01-09 |
$814,000 |
| 11351167 |
Treating cognitive decline and other neurodegenerative conditions by selectively removing senescent cells from neurological tissue |
Remi-Martin Laberge, Judith Campisi, Marco Demaria, James L. Kirkland, Tamar Tchkonia +3 more |
2022-06-07 |
|
| 11202786 |
Synthetic bile acid compositions and methods |
Robert M. Moriarty, Nadir Ahmeduddin Mahmood |
2021-12-21 |
|
| 11129838 |
Methods of inhibiting pathological angiogenesis |
Pam Tsuruda, Jill Hopkins, Harry Sweigard, Yan Poon, Jamie Dananberg +1 more |
2021-09-28 |
$2,523,000 |
| 11026955 |
Synthetic bile acid compositions and methods |
Robert M. Moriarty, Nadir Ahmeduddin Mahmood |
2021-06-08 |
|
| 10588916 |
Technology to inhibit vascular changes that lead to vision loss in the eye |
Pam Tsuruda, Jill Hopkins, Harry Sweigard, Yan Poon, Jamie Dananberg +1 more |
2020-03-17 |
$3,447,000 |
| 10550378 |
Composition comprising a gene vector that selectively depletes P16 positive senescent cells |
Serge Lichtsteiner |
2020-02-04 |
$4,287,000 |
| 10517866 |
Removing senescent cells from a mixed cell population or tissue using a phosphoinositide 3-kinase (PI3K) inhibitor |
Remi-Martin Laberge, James L. Kirkland, Tamar Tchkonia, Yi Zhu, Alain P. Vasserot +3 more |
2019-12-31 |
$2,439,000 |
| 10478433 |
Unit dose of an aryl sulfonamide that is effective for treating eye disease and averting potential vision loss |
Remi-Martin Laberge, Judith Campisi, Marco Demaria, Darren J. Baker, James L. Kirkland +5 more |
2019-11-19 |
$2,314,000 |
| 10478432 |
Compositions of matter for treatment of ophthalmic conditions by selectively removing senescent cells from the eye |
Remi-Martin Laberge, Judith Campisi, Marco Demaria, Alain P. Vasserot, James L. Kirkland +5 more |
2019-11-19 |
$2,314,000 |
| 10434108 |
Synthetic bile acid compositions and methods |
Robert M. Moriarty, Nadir Ahmeduddin Mahmood |
2019-10-08 |
|
| 10434107 |
Synthetic bile acid compositions and methods |
Robert M. Moriarty, Nadir Ahmeduddin Mahmood |
2019-10-08 |
|
| 10426788 |
Chemical entities that kill senescent cells for use in treating age-related disease |
— |
2019-10-01 |
$4,357,000 |
| 10413542 |
Methods and compositions for killing senescent cells and for treating senescence-associated diseases and disorders using an inhibitor of Akt kinase |
Remi-Martin Laberge, Alain P. Vasserot, Darren J. Baker, Bennett G. Childs, James L. Kirkland +3 more |
2019-09-17 |
|
| 10378002 |
Replication conditional virus that specifically kills senescent cells |
Serge Lichtsteiner |
2019-08-13 |
$4,394,000 |
| 10328073 |
Use of sulfonamide inhibitors of BCL-2 and BCL-xL to treat ophthalmic disease by selectively removing senescent cells |
Remi-Martin Laberge, Judith Campisi, Marco Demaria, Alain P. Vasserot, James L. Kirkland +5 more |
2019-06-25 |
$2,770,000 |
| 10328058 |
Treating atherosclerosis by removing senescent foam cell macrophages from atherosclerotic plaques |
Darren J. Baker, Marco Demaria, Albert Davalos, Bennett G. Childs, Jan M.A. van Deursen +5 more |
2019-06-25 |
|
| 10258618 |
Treating pulmonary conditions by selectively removing senescent cells from the lung using an intermittent dosing regimen |
Remi-Martin Laberge, Judith Campisi, Marco Demaria, Darren J. Baker, James L. Kirkland +3 more |
2019-04-16 |
$4,981,000 |
| 10213426 |
Method of optimizing conditions for selectively removing a plurality of senescent cells from a tissue or a mixed cell population |
Remi-Martin Laberge, Judith Campisi, Albert Davalos, Marco Demaria, Yi Zhu +2 more |
2019-02-26 |
$6,280,000 |
| 10195213 |
Chemical entities that kill senescent cells for use in treating age-related disease |
— |
2019-02-05 |
$7,282,000 |
| 10144757 |
Synthetic bile acid compositions and methods |
Robert M. Moriarty, Nadir Ahmeduddin Mahmood |
2018-12-04 |
|
| 10130628 |
Treatment of joint pain |
Albert Davalos, Remi-Martin Laberge, Judith Campisi, Marco Demaria, Alain P. Vasserot +6 more |
2018-11-20 |
$7,742,000 |
