| 12055549 |
Methods of use of anti-TNFα antibodies |
James Philip O'CONNELL, Alastair David Griffiths Lawson, Tracy Lynn Arakaki, Daniel John Lightwood, Rebecca Jayne MUNRO |
2024-08-06 |
| 11674967 |
Method of identifying potential inhibitors of APO TNFα trimers |
James Philip O'CONNELL, Alastair David Griffiths Lawson, Boris Kroeplien, Stephen Edward Rapecki, Timothy John Norman +8 more |
2023-06-13 |
| 11448655 |
Method for identifying a modulator of the TNFα or CD40L interaction with their cognate receptors |
James Philip O'CONNELL, Alastair David Griffiths Lawson, Boris Kroeplien, Stephen Edward Rapecki, Timothy John Norman +1 more |
2022-09-20 |
| 11174311 |
Antibody against trimeric TNFα complex |
Alastair David Griffiths Lawson, Daniel John Lightwood, Rebecca Jayne MUNRO, James Philip O'CONNELL |
2021-11-16 |
| 11022614 |
Antibodies binding to trimeric TNF alpha epitopes |
James Philip O'CONNELL, Alastair David Griffiths Lawson, Tracy Lynn Arakaki, Daniel John Lightwood, Rebecca Jayne MUNRO |
2021-06-01 |
| 10969393 |
Complexes between anti-TNF antibodies, trimeric TNF proteins and organic molecules binding them |
James Philip O'CONNELL, Alastair David Griffiths Lawson, Daniel John Lightwood, Rebecca Jayne MUNRO |
2021-04-06 |
| 10883996 |
Methods of identifying signaling modulators of the trimeric TNFa |
James Philip O'CONNELL, Alastair David Griffiths Lawson, Boris Kroeplien, Stephen Edward Rapecki, Timothy John Norman +4 more |
2021-01-05 |
| 10775385 |
Treatment of autoimmune and inflammatory disorders with asymmetric TNF alpha trimers |
James Philip O'CONNELL, Alastair David Griffiths Lawson, Boris Kroeplien, Stephen Edward Rapecki, Timothy John Norman +8 more |
2020-09-15 |
| 10705094 |
TNF receptor signaling modulator assay |
James Philip O'CONNELL, Alastair David Griffiths Lawson, Boris Kroeplien, Stephen Edward Rapecki, Timothy John Norman +1 more |
2020-07-07 |
| 10287299 |
Substituted benzo[b][1,4]oxazines and pyrido[3,2-b][1,4]oxazines as modulators of tumor necrosis factor activity |
Gareth Neil Brace, Prafulkumar Tulshibhai Chovatia, Gregory Foulkes, James A. Johnson, Severine Danielle Jones +12 more |
2019-05-14 |
| 10093652 |
Tetrahydrobenzimidazole derivatives as modulators of TNF activity |
Jag Paul Heer, Victoria Elizabeth Jackson, Boris Kroeplien, Fabien Claude Lecomte |
2018-10-09 |
| 9988383 |
Purine derivatives as modulators of TNF activity |
Victoria Elizabeth Jackson, Boris Kroeplien, Martin Alexander Lowe |
2018-06-05 |
| 9969729 |
Imidazopyridine derivatives as modulators of TNF activity |
Victoria Elizabeth Jackson, Fabien Claude Lecomte |
2018-05-15 |
| 9969728 |
Tetrahydroimidazopyridine derivatives as modulators of TNF activity |
Sabine Defays, Jag Paul Heer, Victoria Elizabeth Jackson, James A. Johnson, Boris Kroeplien |
2018-05-15 |
| 9932334 |
Tetrahydroimidazopyridine derivatives as modulators of TNF activity |
Victoria Elizabeth Jackson, Boris Kroeplien, Martin Alexander Lowe |
2018-04-03 |
| 9932342 |
Imidazopyrimidine derivatives as modulators of TNF activity |
Mezher Hussein Ali, Daniel Christopher Brookings, Julien Alistair Brown, Victoria Elizabeth Jackson, Boris Kroeplien |
2018-04-03 |
| 9926313 |
Imidazopyridine derivatives as modulators of TNF activity |
Michael Deligny, Jag Paul Heer, Victoria Elizabeth Jackson, Boris Kroeplien, Fabien Claude Lecomte |
2018-03-27 |
| 9920052 |
Imidazopyridine derivatives as modulators of TNF activity |
Victoria Elizabeth Jackson |
2018-03-20 |
| 9890154 |
Imidazopyridine derivatives as modulators of TNF activity |
Victoria Elizabeth Jackson, Boris Kroeplien |
2018-02-13 |
| 9873703 |
Imidazopyridazine derivatives as modulators of TNF activity |
Mezher Hussein Ali, Daniel Christopher Brookings, Julien Alistair Brown, Martin Clive Hutchings, Victoria Elizabeth Jackson +2 more |
2018-01-23 |
| 9868749 |
Fused imidazole and pyrazole derivatives as modulators of TNF activity |
Rikki Peter Alexander, Jonathan Mark Bentley, Gareth Neil Brace, Daniel Christopher Brookings, Prafulkumar Tulshibhai Chovatia +11 more |
2018-01-16 |
| 9834553 |
Tetrahydroimidazopyridine derivatives as modulators of TNF activity |
Victoria Elizabeth Jackson, Boris Kroeplien, Martin Alexander Lowe |
2017-12-05 |
| 9714251 |
Imidazotriazine derivatives as modulators of TNF activity |
Daniel Christopher Brookings, Julien Alistair Brown, Victoria Elizabeth Jackson, Joanna Rachel Quincey |
2017-07-25 |
| 9550737 |
TNF -α modulating benzimidazoles |
Daniel Christopher Brookings, Mark Daniel Calmiano, Ellen Olivia Gallimore, Helen Tracey Horsley, Martin Clive Hutchings +11 more |
2017-01-24 |
| 9475820 |
Substituted imidazo[1,2-a]pyrazines as TNF activity modulators |
Jonathan Mark Bentley, Daniel Christopher Brookings, Julien Alistair Brown, Thomas Paul Cain, Laura Gleave +7 more |
2016-10-25 |