Patent Leaderboard
USPTO Patent Rankings Data through Sept 30, 2025
MH

Michael Heartlein — 173 Patents

TBTranslate Bio: 127 patents #2 of 46Top 5%
TTTranskaryotic Therapies: 26 patents #3 of 15Top 20%
STShire Human Genetic Therapies: 13 patents #4 of 130Top 4%
EGEthris Gmbh: 5 patents #5 of 18Top 30%
MIT: 4 patents #1,242 of 9,367Top 15%
SBSynageva Biopharma: 1 patents #12 of 30Top 40%
TLTakeda Pharmaceutical Company Limited: 1 patents #859 of 1,531Top 60%
Lexington, MA: #4 of 2,299 inventorsTop 1%
Massachusetts: #65 of 88,656 inventorsTop 1%
Overall (All Time): #4,595 of 4,157,543Top 1%
173 Patents All Time

Issued Patents All Time

Showing 126–150 of 173 patents

Patent #TitleCo-InventorsDate
9956271 mRNA for use in treatment of human genetic diseases Braydon Charles Guild, Frank DeRosa 2018-05-01
9943595 Messenger RNA therapy for treatment of articular disease Frank DeRosa 2018-04-17
9932377 Mitochondrial targeting and therapeutic use thereof Dennis Keefe, Michael F. Concino, Serene Josiah, Bettina Strack-Logue 2018-04-03
9877919 Lipid-derived neutral nanoparticles Frank DeRosa, Braydon Charles Guild 2018-01-30
9850269 Methods for purification of messenger RNA Frank DeRosa, Anusha Dias, Shrirang Karve 2017-12-26
9719074 Cells for producing recombinant iduronate-2-sulfatase Ferenc Boldog 2017-08-01
9717690 Cleavable lipids Braydon Charles Guild, Frank DeRosa, Jerry Chi Zhang 2017-08-01
9713626 CFTR mRNA compositions and related methods and uses Braydon Charles Guild, Frank DeRosa, Carsten Rudolph, Christian Plank, Lianne Smith 2017-07-25
9668980 Encapsulation of messenger RNA Frank DeRosa, Shrirang Karve 2017-06-06
9629804 Lipid formulations for delivery of messenger RNA Daniel Griffith Anderson, Yizhou Dong, Frank DeRosa 2017-04-25
9597413 Pulmonary delivery of mRNA Braydon Charles Guild, Frank DeRosa 2017-03-21
9546128 Ionizable cationic lipids Frank DeRosa, Braydon Charles Guild 2017-01-17
9522176 MRNA therapy for phenylketonuria Frank DeRosa, Anusha Dias 2016-12-20
9308281 MRNA therapy for Fabry disease Braydon Charles Guild, Frank DeRosa 2016-04-12
9260495 Mitochondrial targeting and therapeutic use thereof Dennis Keefe, Michael F. Concino, Serene Josiah, Bettina Strack-Logue 2016-02-16
9181321 CFTR mRNA compositions and related methods and uses Braydon Charles Guild, Frank DeRosa, Carsten Rudolph, Christian Plank, Lianne Smith 2015-11-10
9150841 Cells for producing recombinant iduronate-2-sulfatase Ferenc Boldog 2015-10-06
9061021 mRNA for use in treatment of human genetic diseases Braydon Charles Guild, Frank DeRosa 2015-06-23
8945542 Methods for treating lysosomal acid lipase deficiency Michael F. Concino, Paolo Martini, Muthuraman Meiyappan, Pericles Calias, Alla Romashko +5 more 2015-02-03
8853377 mRNA for use in treatment of human genetic diseases Braydon Charles Guild 2014-10-07
8227212 Cell that expresses a sulfatase and a formylglycine generating enzyme Kurt von Figura, Bernhard Schmidt, Thomas Dierks, Maria Pia Cosma, Andrea Ballabio 2012-07-24
7410799 In vivo production and delivery of erythropoietin or insulinotropin for gene therapy Richard F. Selden, Douglas A. Treco 2008-08-12
6858578 Chimeric proteins for use in transport of a selected substance into cells Jeffrey F. Lemontt, Michael F. Concino 2005-02-22
6846676 In Vivo production and delivery of erythropoietin or insulinotropin for gene therapy Richard F. Selden, Douglas A. Treco 2005-01-25
6692737 In vivo protein production and delivery system for gene therapy Richard F. Selden, Douglas A. Treco 2004-02-17