Issued Patents All Time
Showing 1–12 of 12 patents
| Patent # | Title | Co-Inventors | Date |
|---|---|---|---|
| 12258595 | Systems, methods and compositions for sequence manipulation with optimized functional CRISPR-Cas systems | Silvana Konermann, Alexandro Trevino, Mark Brigham, Fei Ran, Patrick Hsu +4 more | 2025-03-25 |
| 12168789 | Engineering and optimization of systems, methods, enzymes and guide scaffolds of CAS9 orthologs and variants for sequence manipulation | Feng Zhang, Winston X. Yan, Kaijie Zheng, Le Cong, Hiroshi Nishimasu +2 more | 2024-12-17 |
| 12152259 | Modified CAS9 protein, and use thereof | Hiroshi Nishimasu, Hisato HIRANO, Shohei KAJIMOTO, Tetsuya YAMAGATA, Yuanbo QIN +2 more | 2024-11-26 |
| 11702645 | Polynucleotide encoding modified CAS9 protein | Hiroshi Nishimasu, Hisato HIRANO | 2023-07-18 |
| 11597919 | Systems, methods and compositions for sequence manipulation with optimized functional CRISPR-Cas systems | Silvana Konermann, Alexandro Trevino, Mark Brigham, Fei Ran, Patrick Hsu +4 more | 2023-03-07 |
| 11578312 | Engineering and optimization of systems, methods, enzymes and guide scaffolds of CAS9 orthologs and variants for sequence manipulation | Feng Zhang, Winston X. Yan, Kaijie Zheng, Le Cong, Hiroshi Nishimasu +2 more | 2023-02-14 |
| 11530396 | Modified CAS9 protein, and use thereof | Hiroshi Nishimasu, Hisato HIRANO, Shohei KAJIMOTO, Tetsuya YAMAGATA, Yuanbo QIN +2 more | 2022-12-20 |
| 11371030 | Modified Cas9 protein and use thereof | Hiroshi Nishimasu, Hisato HIRANO | 2022-06-28 |
| 11155795 | CRISPR-Cas systems, crystal structure and uses thereof | Feng Zhang, Hiroshi Nishimasu, Ryuichiro ISHITANI | 2021-10-26 |
| 10550372 | Systems, methods and compositions for sequence manipulation with optimized functional CRISPR-Cas systems | Silvana Konermann, Alexandro Trevino, Mark Brigham, Fei Ran, Patrick Hsu +4 more | 2020-02-04 |
| 10189843 | Fused pyrazole derivative having autotaxin inhibitory activity | Tetsuo Nagano, Takayoshi Okabe, Hirotatsu Kojima, Mitsuyasu KAWAGUCHI, Ryuichiro ISHITANI +8 more | 2019-01-29 |
| 10183949 | Pyrimidinone derivative having autotaxin-inhibitory activity | Tetsuo Nagano, Takayoshi Okabe, Hirotatsu Kojima, Mitsuyasu KAWAGUCHI, Ryuichiro ISHITANI +8 more | 2019-01-22 |