Issued Patents All Time
Showing 1–25 of 42 patents
| Patent # | Title | Co-Inventors | Date |
|---|---|---|---|
| 12060360 | Lysyl oxidase inhibitors | Richard Marais, Dan Niculescu-Duvaz, Natalie Miller, Mohammed Aljarah, Alfonso Zambon +4 more | 2024-08-13 |
| 12018029 | Hexahydropyrrolo[3,4-c]pyrrole derivatives useful as LOX inhibitors | Leo Leung, Kiri North, Deborah Smithen, Mohammed Aljarah, Michael S. Brown +2 more | 2024-06-25 |
| 11608330 | Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer | Richard Marais, Dan Niculescu-Duvaz, Leo Leung, Deborah Smithen, Cedric Callens +1 more | 2023-03-21 |
| 11325915 | Lysyl oxidase inhibitors | Richard Marais, Dan Niculescu-Duvaz, Natalie Miller, Mohammed Aljarah, Alfonso Zambon +4 more | 2022-05-10 |
| 10995088 | Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer | Richard Marais, Dan Niculescu-Duvaz, Leo Leung, Deborah Smithen, Cedric Callens +1 more | 2021-05-04 |
| 10807974 | Methylamine derivatives as lysysl oxidase inhibitors for the treatment of cancer | Richard Marais, Dan Niculescu-Duvaz, Leo Leung, Deborah Smithen, Cedric Callens +1 more | 2020-10-20 |
| 10167282 | 1-(5-tert-butyl-2-aryl-pyrazol-3-yl)-3-[2-fluoro-4-[(3-oxo-4H-pyrido [2, 3-B]pyrazin- 8-yl)oxy]phenyl]urea derivatives as RAF inhibitors for the treatment of cancer | Richard Marais, Romina Girotti, Dan Niculescu-Duvaz, Ion Niculescu-Duvaz, Alfonso Zambon | 2019-01-01 |
| 10100053 | Process for the preparation of 8-(4-aminophenoxy)-4H-pyrido[2,3-b]pyrazin-3-one derivatives | Alfonso Zambon, Dan Niculescu-Duvaz, Richard Chubb | 2018-10-16 |
| 9820976 | 1-(5-tert-butyl-2-phenyl-2H-pyrazol-3-yl)-3-[2-fluoro-4-(1-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)-phenyl]-urea and related compounds and their use in therapy | Ion Niculescu-Duvaz, Richard Marais, Dan Niculescu-Duvaz, Alfonso Zambon, Delphine Menard | 2017-11-21 |
| 9725447 | 1-(5-tert-butyl-2-aryl-pyrazol-3-yl)-3-[2-fluoro-4-[(3-oxo-4H-pyrido[2,3-b]pyrazin-8-yl)oxy]phenyl]urea derivatives as RAF inhibitors for the treatment of cancer | Richard Marais, Romina Girotti, Dan Niculescu-Duvaz, Ion Niculescu-Duvaz, Alfonso Zambon | 2017-08-08 |
| 9708317 | Process for the preparation of 8-(4-aminophenoxy)-4H-pyrido[2,3-B]pyrazin-3-one derivatives | Alfonso Zambon, Dan Niculescu-Duvaz, Richard Chubb | 2017-07-18 |
| 9540372 | Pyrido[2,3-b]pyrazin-8-substituted compounds and their use | Dan Niculescu-Duvaz, Ion Niculescu-Duvaz, Richard Marais, Bartholomeus Marinus Josephus Marie Suijkerbuijk, Alfonso Zambon +2 more | 2017-01-10 |
| 9439893 | 1-(5-tert-butyl-2-phenyl-2H-pyrazol-3-yl)-3-[2-fluoro-4-(1-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-B]pyridin-7-yloxy)-phenyl]-urea and related compounds and their use in therapy | Ion Niculescu-Duvaz, Richard Marais, Dan Niculescu-Duvaz, Alfonso Zambon, Delphine Menard | 2016-09-13 |
| 9155737 | Pyrido[2,3-B]pyrazin-8-substituted compounds and their use | Dan Niculescu-Duvaz, Ion Niculescu-Duvaz, Richard Marais, Bartholomeus Marinus Josephus Marie Suijkerbuijk, Alfonso Zambon +2 more | 2015-10-13 |
| 9120789 | 1-(5-tert-butyl-2-phenyl-2H-pyrazol-3-yl)-3-[2-fluoro-4-(1-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-7-yloxy)-phenyl]-urea and related compounds and their use in therapy | Ion Niculescu-Duvaz, Richard Marais, Dan Niculescu-Duvaz, Alfonso Zambon, Delphine Menard | 2015-09-01 |
| 8912191 | Pyrido[2,3-B]pyrazin-8-substituted compounds and their use | Dan Niculescu-Duvaz, Ion Niculescu-Duvaz, Richard Marais, Bartholomeus Marinus Josephus Marie Suijkerbuijk, Alfonso Zambon +2 more | 2014-12-16 |
| 8815896 | 1-(5-tert-butyl-2-phenyl-2H-pyrazol-3-yl)-3-[2-fluoro-4-(1-methyl-2-oxo-2,3-dihydro-1H-imidazo[4,5-B]pyridin-7-yloxy)-phenyl]-urea and related compounds and their use in therapy | Ion Niculescu-Duvaz, Richard Marais, Dan Niculescu-Duvaz, Alfonso Zambon, Delphine Menard | 2014-08-26 |
| 8546387 | Pyrido[2,3-b]pyrazin-8-substituted compounds and their use | Dan Niculescu-Duvaz, Ion Niculescu-Duvaz, Richard Marais, Bartholomeus Marinus Josephus Marie Suijkerbuijk, Alfonso Zambon +2 more | 2013-10-01 |
| 8383816 | Aryl-quinolyl compounds and their use | Ion Niculescu-Duvaz, Alfonso Zambon, Dan Niculescu-Duvaz, Steven Whittaker, Richard Marais | 2013-02-26 |
| 8198279 | Pyrido[2,3-b]pyrazin-8-substituted compounds and their use | Dan Niculescu-Duvaz, Ion Niculescu-Duvaz, Richard Marais, Bartholomeus Marinus Josephus Marie Suijkerbuijk, Alfonso Zambon +2 more | 2012-06-12 |
| 7951819 | Imidazo[4, 5-B]pyridin-2-one and oxazolo[4, 5-B] pyridin-2-one compounds and analogs thereof as cancer therapeutic compounds | Dan Niculescu-Duvaz, Richard Marais, Harmen Dijkstra, Delphine Menard, Ion Niculescu-Duvaz +2 more | 2011-05-31 |
| 7737152 | 6-carboaryl-oxy-pyrazin-2-yl-carboaryl-amines and compositions comprising said compounds | Ion Niculescu-Duvaz, Esteban Roman Vela, Adrian Liam Gill, Richard David Taylor, Richard Marais | 2010-06-15 |
| 7625922 | Imidazo[4,5-b]pyridin-2-one and oxazolo[4,5-b]pyridin-2-one compounds and analogs thereof as therapeutic compounds | Dan Niculescu-Duvaz, Adrian Liam Gill, Richard David Taylor, Richard Marais, Harmen Dijkstra +3 more | 2009-12-01 |
| 7235585 | Enzyme activated self-immolative n-substituted nitrogen mustard prodrugs | Ion Niculescu-Duvaz, Dan Niculescu-Duvaz | 2007-06-26 |
| 6916949 | Methods of chemical systhesis of phenolic nitrogen mustard prodrugs | Dan Niculescu-Duvaz | 2005-07-12 |