| 12466810 |
N-(5-(6-ethoxypyrazin-2-yl)pyridin-2-yl)-4-(2-(methylsulfonamido)pyrimidin-4-yl) tetrahydro-2H-pyran-4-carboxamide derivatives and related compounds as human CTPS1 inhibitors for the treatment of proliferative diseases |
Abdul Quddus, Andrew Novak, David Cousin, Emma Blackham, Geraint Jones +4 more |
2025-11-11 |
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| 12398129 |
Imidazolone derivatives as inhibitors of protein kinases in particular DYRK1A, CLK1 and/or CLK4 |
Emmanuel DEAU, Laurent Meijer, Frederic Miege |
2025-08-26 |
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| 11655246 |
Aminothiazole compounds as inhibitors of CTPS1 |
Abdul Quddus, Andrew Novak, David Cousin, Elli CHATZOPOULOU, Emma Blackham +6 more |
2023-05-23 |
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| 11505547 |
Compounds |
Andrew Novak, Geraint Jones, Joseph Wrigglesworth, Lorna Duffy, Louise Birch |
2022-11-22 |
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| 8846676 |
6-cycloamino-3-(pyrid-4-yl)imidazo[1,2-b]pyridazine derivatives, preparation thereof and therapeutic use thereof |
Antonio Almario Garcia, Mathieu Barrague, Philippe Burnier, Cecile Enguehard-Gueiffier, Zhongli Gao +5 more |
2014-09-30 |
$6,701,000 |
| 8354405 |
6-cycloamino-3-(pyrid-4-yl)imidazo[1,2-b]pyridazine derivatives, preparation thereof and therapeutic use thereof |
Antonio Almario Garcia, Matthieu Barrague, Philippe Burnier, Cécile Enguehard, Zhongli Gao +5 more |
2013-01-15 |
$21,800,000 |
| 7507743 |
Substituted 8′-pyridinyl-dihydrospiro-[cycloalkyl]-pyrimido[1,2-a] pyrimidin-6-one and 8′-pyrimidinyl-dihydrospiro-[cycloalkyl]-pyrimido[1,2-a] pyrimidin-6-one derivatives |
Alistair Lochead, Mourad Saady, Franck Slowinski, Philippe Yaiche |
2009-03-24 |
$23,117,000 |
| 7476756 |
Alkyl-, alkenyl- and alkynylcarbamate derivatives, their preparation and their application in therapeutics |
Antonio Almario-Garcia, Christian Hoornaert, Adrien Tak Li, Frederic Puech |
2009-01-13 |
$27,858,000 |
| 7294632 |
Substituted 8′-pyridinyl-dihydrospiro-[cycloalkyl]-pyrimido[1,2-a]pyrimidin-6-one and 8′-pyrimidinyl-dihydrospiro-[cycloalkyl]-pyrimido[1,2-a]pyrimidin-6-one derivatives |
Alistair Lochead, Mourad Saady, Franck Slowinski, Philippe Yaiche |
2007-11-13 |
$8,960,000 |
| 6221879 |
8-azabicyclo[3.2.1] octane-3-methanamine derivatives as ligands of D2 and D3 dopamine and 5HT1A and 5HT2 serotonin receptors |
Benoit Marabout, Mireille Sevrin, Jean-Pierre Merly, Daniele De Peretti, Jocelyne Roy +1 more |
2001-04-24 |
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| 6075021 |
1H-pyrido[3,4-b]indole-4-carboxamide derivatives, preparation and application thereof in therapeutics |
Yannick Evanno, Mireille Sevrin, Christian Maloizel, Odette Legalloudec |
2000-06-13 |
|
| 5929078 |
1-2-(2,3-Dihydro-1H-inden-1-yl)ethyl!-4-(naphthalen-1-yl) piperazine, derivatives, preparation thereof and therapeutical use thereof |
Mireille Sevrin, Philippe Manoury, Michel Peynot, Daniele De Peretti, Jean-Francois Gibert +2 more |
1999-07-27 |
|
| 5922739 |
5-Naphthalen-1-yl-1,3-dioxane derivatives, preparation and therapeutical use thereof |
Gihad Dargazanli, Yannick Evanno, Jonathan Frost, Patrick Lardenois, Mireille Sevrin |
1999-07-13 |
|
| 5663183 |
N-(3-Aminopropyl)-N-phenyl-5,6,7,8-tetrahydronaphthalene-2-carboxamide derivatives, their preparation and their therapeutic use |
Jonathan Frost, Patrick Pasau, Regine Bartsch, Corinne Rousselle, Paul H. Williams +1 more |
1997-09-02 |
|
| 5652248 |
Method of preventing peripheral neuropathies induced by anticancer agents |
Delphine Lekieffre, Jesus Benavides, Bernard Scatton |
1997-07-29 |
|
| 5550162 |
N-(-3-aminopropyl)-N-phenyl-5,6,7,8-tetrahydro-naphthalene-2-carboxamide derivatives, their preparation and their therapeutic use |
Jonathan Frost, Patrick Pasau, R egine Bartsch, Corinne Rousselle, Paul H. Williams +1 more |
1996-08-27 |
|
| 5550125 |
3-(2-aminomethyl)-4-[3-trifluoromethyl)benzoyl]-3-4 dihydro-2h-1,4-benzoxazine derivatives and their therapeutic application |
Jonathan Frost, Patrick Pasau, Corinne Rousselle, R egine Bartsch, Paul H. Williams +1 more |
1996-08-27 |
|
| 5543421 |
Method of treatment of peripheral neuropathies and central neurodegenerative diseases |
J esus Benavides, Badia Ferzaz, Bernard Scatton |
1996-08-06 |
|
| 5530002 |
1-[2-(1H-inden-3-yl)ethyl]-4-(naphth-1-yl)piperazine derivatives, their preparation and their application in therapeutics |
Phillip Manoury, Daniel Obitz, Michel Peynot, Mireille Sevrin |
1996-06-25 |
|
| 5512590 |
5,6-dihydro-4h-imidazo 2',1':2,3!imidazo- 4,5,1-ij!quinoline and 4,5-dihydroimidazo- 1,2-a!pyrolo 1,2,3-cd!benzimidazole derivatives, their preparation and application in therapeutics |
Mireille Sevrin, Michel Peynot |
1996-04-30 |
|
| 5466706 |
9H-imidazo[1,2-A]benzimidazole-3-acetamide derivatives, their preparation and their therapeutic application |
Danielle De Peretti, Jocelyne Roy, Jean-Paul Schmitt, Mireille Sevrin |
1995-11-14 |
|
| 5447928 |
Benzoxazine derivatives and their application in therapy |
Howard Williams, Lydia Zard, Thomas Purcell, Daniel Galtier, Jean-Claude Muller +4 more |
1995-09-05 |
|
| 5420130 |
2-aminopyrazine-5-carboxamide derivatives, their preparation and their application in therapeutics |
Benoit Marabout, Jacques Froissant |
1995-05-30 |
|
| 5418248 |
2-thienylimidazo[2,1-.beta.]benzothiazole-3-acetic acid derivatives, their preparation and their use |
Mireille Sevrin, Claude Morel, Michel Mangane |
1995-05-23 |
|
| 5330985 |
2-amino-N- [[4-(aminocarbonyl)pyrimidin-2-yl]amino]-alkyl]pyrimidine-4-carboxamide derivatives, their preparation and pharmaceutical compositions containing them |
Benoit Marabout, Jacques Froissant, Jean-Pierre Merly |
1994-07-19 |
|