Missouri ranks #23 among US states for total patents filed all time, with 103,774 patents from 23,789 inventors across 671 cities. On a per-capita basis that is 16.9 patents per 1,000 residents, a standard benchmark for comparing state-level R&D intensity.
Top Cities in Missouri All Time
| Rank | City | Patents | Inventors |
|---|---|---|---|
| #1 | Chesterfield, MO | 29,443 | 6,461 |
| #2 | Kansas City, MO | 6,462 | 1,876 |
| #3 | Holden, MO | 4,528 | 898 |
| #4 | Columbia, MO | 4,039 | 885 |
| #5 | Ballwin, MO | 3,103 | 595 |
| #6 | O'Fallon, MO | 2,562 | 454 |
| #7 | Lee's Summit, MO | 2,364 | 514 |
| #8 | Wildwood, MO | 2,216 | 309 |
| #9 | Saint Peters, MO | 2,025 | 433 |
| #10 | Creve Coeur, MO | 1,789 | 236 |
| #11 | Springfield, MO | 1,695 | 510 |
| #12 | Manchester, MO | 1,568 | 278 |
| #13 | Rolla, MO | 1,512 | 363 |
| #14 | Florissant, MO | 1,508 | 452 |
| #15 | Webster Groves, MO | 1,352 | 205 |
| #16 | Kirkwood, MO | 1,340 | 290 |
| #17 | Maryland Heights, MO | 1,223 | 213 |
| #18 | Fenton, MO | 1,027 | 221 |
| #19 | University City, MO | 1,014 | 191 |
| #20 | Joplin, MO | 950 | 249 |
| #21 | Independence, MO | 944 | 256 |
| #22 | Saint Louis, MO | 846 | 229 |
| #23 | Platte City, MO | 813 | 107 |
| #24 | Blue Springs, MO | 799 | 228 |
| #25 | Eureka, MO | 762 | 119 |