Issued Patents All Time
Showing 1–25 of 62 patents
| Patent # | Title | Co-Inventors | Date |
|---|---|---|---|
| 11884930 | Method of inactivating a glucocorticoid receptor gene in an isolated cell | Andreas Reik, Michael C. Jensen, Michael C. Holmes, Dale Ando | 2024-01-30 |
| 11661612 | DNA-binding proteins and uses thereof | Jeffrey C. Miller, David Paschon, Edward J. Rebar, Siyuan Tan, Fyodor Urnov +1 more | 2023-05-30 |
| 11649468 | Targeted integration into the PPP1R12C locus | Russell DeKeiver, David Paschon, Phillip Tam, Fyodor Urnov | 2023-05-16 |
| 11492643 | Methods and compositions for treatment of a genetic condition | Gregory J. Cost, Dmitry Guschin, Michael C. Holmes, Jeffrey C. Miller, David Paschon +4 more | 2022-11-08 |
| 11439666 | Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases | Maria Chiara Bonini, Pietro Genovese, Michael C. Holmes, Luigi Naldini, David Paschon +2 more | 2022-09-13 |
| 11235026 | Methods and compositions for modulating PD1 | Michael C. Holmes, Matthew C. Mendel, Xiangdong Meng, David Paschon, Andreas Reik +1 more | 2022-02-01 |
| 11236175 | T cell modifying compounds and uses thereof | Michael C. Holmes | 2022-02-01 |
| 10918668 | Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases | Michael C. Holmes, David Paschon, Lei Zhang, Maria Chiara Bonini, Pietro Genovese +3 more | 2021-02-16 |
| 10907175 | Isolated human cell with an inactivated glucocorticoid receptor gene | Andreas Reik, Michael C. Jensen, Michael C. Holmes, Dale Ando | 2021-02-02 |
| 10858416 | Methods and compositions for modification of a HLA locus | Trevor Collingwood, Laurence J.N. COOPER, Michael C. Holmes, Jeffrey C. Miller, Edward J. Rebar +2 more | 2020-12-08 |
| 10646543 | Methods and compositions for treating trinucleotide repeat disorders | Edward J. Rebar, H. Steve Zhang | 2020-05-12 |
| 10253333 | DNA-binding proteins and uses thereof | Jeffrey C. Miller, David Paschon, Edward J. Rebar, Siyuan Tan, Fyodor Urnov +1 more | 2019-04-09 |
| 10155011 | Targeted disruption of T cell receptor genes using engineered zinc finger protein nucleases | Maria Chiara Bonini, Pietro Genovese, Michael C. Holmes, Luigi Naldini, David Paschon +2 more | 2018-12-18 |
| 10117899 | Delivery methods and compositions for nuclease-mediated genome engineering in hematopoietic stem cells | Pietro Genovese, Michael C. Holmes, Angelo Leone Lombardo, Luigi Naldini | 2018-11-06 |
| 10072062 | Methods and compositions for modification of a HLA locus | Trevor Collingwood, Laurence J.N. COOPER, Michael C. Holmes, Jeffrey C. Miller, Edward J. Rebar +2 more | 2018-09-11 |
| 10046028 | Methods and compositions for modulating PD1 | Michael C. Holmes, Matthew C. Mendel, Xiangdong Meng, David Paschon, Andreas Reik +1 more | 2018-08-14 |
| 9963715 | Methods and compositions for treatment of a genetic condition | Gregory J. Cost, Dmitry Guschin, Michael C. Holmes, Jeffrey C. Miller, David Paschon +4 more | 2018-05-08 |
| 9943565 | Methods and compositions for treating trinucleotide repeat disorders | Edward J. Rebar, H. Steve Zhang | 2018-04-17 |
| 9937207 | Targeted disruption of T cell receptor genes using talens | Michael C. Holmes, David Paschon, Lei Zhang, Maria Chiara Bonini, Pietro Genovese +3 more | 2018-04-10 |
| 9914940 | Targeted integration into the PPP1R12C locus | Russell DeKelver, David Paschon, Phillip Tam, Fyodor Urnov | 2018-03-13 |
| 9834787 | Targeted integration into stem cells | Dirk Hockemeyer, Michael C. Holmes, Rudolf Jaenisch, Frank Soldner, Fyodor Urnov +1 more | 2017-12-05 |
| 9816074 | Methods and compositions for modulating nuclease-mediated genome engineering in hematopoietic stem cells | Anthony J. Conway, Gregory J. Cost | 2017-11-14 |
| 9783827 | DNA-binding proteins and uses thereof | Jeffrey C. Miller, David Paschon, Edward J. Rebar, Siyuan Tan, Fyodor Urnov +1 more | 2017-10-10 |
| 9765360 | Linear donor constructs for targeted integration | Russell DeKelver, Michael C. Holmes, Fyodor Urnov | 2017-09-19 |
| 9757420 | Gene editing for HIV gene therapy | Jianbin Wang, Paula Cannon | 2017-09-12 |