Issued Patents All Time
Showing 1–25 of 34 patents
| Patent # | Title | Co-Inventors | Date |
|---|---|---|---|
| 12065661 | Genetic modification of rats | Jeffrey D. Lee, David Heslin, David Frendewey, Ka-Man Venus Lai, David M. Valenzuela | 2024-08-20 |
| 12060571 | Methods and compositions for modifying a targeted locus | David Frendewey, Gustavo Droguett, Anthony Gagliardi, Junko Kuno, David M. Valenzuela | 2024-08-13 |
| 12041918 | Production of fertile XY female animals by silencing of genes on the Y chromosome | Jennifer Schmahl, David Frendewey, Junko Kuno, Chia-Jen Siao, Gustavo Droguett +1 more | 2024-07-23 |
| 12037596 | Targeted modification of rat genome | Jeffrey D. Lee, Alexander O. Mujica, Ka-Man Venus Lai, David M. Valenzuela, George D. Yancopoulos | 2024-07-16 |
| 11820997 | Methods and compositions for the targeted modification of a genome | David Frendewey, Ka-Man Venus Lai, David M. Valenzuela, George D. Yancopoulos | 2023-11-21 |
| 11697828 | Methods and compositions for targeted genetic modification using paired guide RNAs | David Frendewey, Ka-Man Venus Lai, Gustavo Droguett, Anthony Gagliardi, David M. Valenzuela +4 more | 2023-07-11 |
| 10975390 | Targeted modification of rat genome | Jeffrey D. Lee, Alexander O. Mujica, Ka-Man Venus Lai, David M. Valenzuela, George D. Yancopoulos | 2021-04-13 |
| 10893666 | Production of fertile XY female animals by silencing of genes on the Y chromosome | Jennifer Schmahl, David Frendewey, Junko Kuno, Chia-Jen Siao, Gustavo Droguett +1 more | 2021-01-19 |
| 10894965 | Genetic modification of rats | Jeffrey D. Lee, David Heslin, David Frendewey, Ka-Man Venus Lai, David M. Valenzuela | 2021-01-19 |
| 10793874 | Methods and compositions for targeted genetic modifications and methods of use | David Frendewey, Gustavo Droguett, Anthony Gagliardi, Junko Kuno, David M. Valenzuela | 2020-10-06 |
| 10711280 | Methods and compositions for the targeted modification of a mouse ES cell genome | David Frendewey, Ka-Man Venus Lai, David M. Valenzuela, George D. Yancopoulos | 2020-07-14 |
| 10457960 | Methods and compositions for targeted genetic modification using paired guide RNAs | David Frendewey, Ka-Man Venus Lai, Gustavo Droguett, Anthony Gagliardi, David M. Valenzuela +4 more | 2019-10-29 |
| 10428310 | Methods and compositions for generating or maintaining pluripotent cells | Junko Kuno, David M. Valenzuela | 2019-10-01 |
| 10385359 | Targeted modification of rat genome | Jeffrey D. Lee, Alexander O. Mujica, Ka-Man Venus Lai, David M. Valenzuela, George D. Yancopoulos | 2019-08-20 |
| 10329582 | Genetic modification of rats | Jeffrey D. Lee, David Heslin, David Frendewey, Ka-Man Venus Lai, David M. Valenzuela | 2019-06-25 |
| 10301646 | Nuclease-mediated targeting with large targeting vectors | David Frendewey, David M. Valenzuela, George D. Yancopoulos, Ka-Man Venus Lai | 2019-05-28 |
| 10294494 | Methods and compositions for modifying a targeted locus | David Frendewey, Gustavo Droguett, Anthony Gagliardi, Junko Kuno, David M. Valenzuela | 2019-05-21 |
| 10208317 | Methods and compositions for the targeted modification of a mouse embryonic stem cell genome | David Frendewey, Ka-Man Venus Lai, David M. Valenzuela, George D. Yancopoulos | 2019-02-19 |
| 10106820 | Methods and compositions for modifying a targeted locus | David Frendewey, Gustavo Droguett, Anthony Gagliardi, Junko Kuno, David M. Valenzuela | 2018-10-23 |
| 10039269 | Methods and compositions for generating a mouse | William Poueymirou, Thomas M. DeChiara, David Frendewey, David M. Valenzuela | 2018-08-07 |
| 9902971 | Methods for producing a mouse XY embryonic (ES) cell line capable of producing a fertile XY female mouse in an F0 generation | David Frendewey, Gustavo Droguett, Anthony Gagliardi, Junko Kuno, David M. Valenzuela | 2018-02-27 |
| 9885058 | Production of fertile XY female mice from XY mouse ES cells | Thomas M. DeChiara, William Poueymirou, David Frendewey, David M. Valenzuela | 2018-02-06 |
| 9834786 | Nuclease-mediated targeting with large targeting vectors | David Frendewey, David M. Valenzuela, George D. Yancopoulos, Ka-Man Venus Lai | 2017-12-05 |
| 9730434 | Methods and compositions for generating a mouse | William Poueymirou, Thomas M. DeChiara, David Frendewey, David M. Valenzuela | 2017-08-15 |
| 9655351 | Production of fertile XY female animals from XY ES cells | Thomas M. DeChiara, William Poueymirou, David Frendewey, David M. Valenzuela | 2017-05-23 |